{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T07:03:55Z","timestamp":1757574235359,"version":"3.41.2"},"reference-count":34,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T00:00:00Z","timestamp":1687132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Haemorrhoidal disease (HD) affects a considerable portion of the adult population. The aim of this study is to confirm the safety and efficacy of the treatments and to report the long-term outcomes of Sclerotherapy (ST) and Mucopexy and Haemorrhoidal Dearterialization (MHD) performed over the last 4 years in a single tertiary centre. The secondary outcome is to evaluate the usefulness of both techniques and to demonstrate how those can be associated as a bridge to surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Patients affected by second\u2013third-degree haemorrhoids and undergoing ST or non-Doppler guided MHD between 2018 and 2021 were enrolled. Safety and efficacy, recurrence rate, Haemorrhoid Severity Score (HSS) and pain resulting from both techniques were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 259 patients, 150 underwent ST. Further, 122 (81.3%) patients were male and 28 (18.7%) were female. The mean age was 50.8 (range 34\u201368) years. Most of the patients (103, 68.6%) were affected by second-degree HD, while 47 (31.4%) were affected by third-degree HD. The overall success rate was 83.3%. The median pre-operative HSS score was 3 (IQR 0\u20134, <jats:italic>p<\/jats:italic>\u2009=\u20090.04) and at 2 year the median HSS was 0 (IQR 0\u20131, <jats:italic>p<\/jats:italic>\u2009=\u20090.03). No intraoperative complications and no drug-related side effects occurred. The mean follow-up for ST was 2 years (range 1\u20134; SD \u00b10.88). MHD was performed on 109 patients. In detail, 80 patients (73.4%) were male while 29 patients (26.6%) were female. The mean age in this group was 51.3 (range 31\u201369). Further, 72 patients (66.1%) were affected by third-degree HD and 37 (33.9%) by second-degree HD. The median HSS score was 9 (IQR 8\u201310, <jats:italic>p<\/jats:italic>\u2009=\u20090.001) preoperatively two years after treatment was 0 (IQR 0\u20131, <jats:italic>p<\/jats:italic>\u2009=\u20090.004). Major complications occurred in three patients (2.75%). The overall success rate was 93.5% (second degree 89.2% vs. third degree 95.8%). The mean follow-up for MHD was 2 years (range 1\u20134; SD \u00b10.68).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results confirm the usefulness of those techniques, which can be considered safe and easily repeatable procedures, with a low recurrence rate after 2 years of median follow-up.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2023.1151327","type":"journal-article","created":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T08:09:26Z","timestamp":1687162166000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Results of sclerotherapy and mucopexy with haemorrhoidal dearterialization in II and III degree haemorrhoids. A 4 years' single centre experience"],"prefix":"10.3389","volume":"10","author":[{"given":"Pierluigi","family":"Lobascio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Laforgia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Pezzolla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,6,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.2174\/1574887115666200312163940","article-title":"Classifications and clinical assessment of haemorrhoids: the Proctologist's Corner","volume":"16","author":"Picciariello","year":"2021","journal-title":"Rev Recent Clin Trials"},{"key":"B2","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1111\/codi.14975","article-title":"European Society of ColoProctology: guideline for haemorrhoidal disease","volume":"22","author":"van Tol","year":"2020","journal-title":"Colorectal Dis"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1111\/codi.14339","article-title":"Surgical management of haemorrhoids: an Italian survey of over 32 000 patients over 17 years","volume":"20","author":"Altomare","year":"2018","journal-title":"Colorectal Dis"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1080\/08941939.2020.1745964","article-title":"Short-Term results of sclerotherapy with 3% polidocanol foam for symptomatic second- and third-degree hemorrhoidal disease","volume":"34","author":"Lobascio","year":"2021","journal-title":"J Invest Surg"},{"key":"B5","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1007\/s10151-022-02609-w","article-title":"A multicentre, open-label, single-arm phase II trial of the efficacy and safety of sclerotherapy using 3% polidocanol foam to treat second-degree haemorrhoids (SCLEROFOAM)","volume":"26","author":"Gallo","year":"","journal-title":"Tech Coloproctol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1007\/s10151-017-1726-5","article-title":"Transanal haemorrhoidal dearterialization (THD) for hemorrhoidal disease: a single-center study on 1000 consecutive cases and a review of the literature","volume":"21","author":"Ratto","year":"2017","journal-title":"Tech Coloprocol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1007\/s13304-020-00860-0","article-title":"Deadlock of proctologic practice in Italy during COVID-19 pandemic: a national report from ProctoLock2020","volume":"72","author":"Gallo","year":"2020","journal-title":"Updates Surg"},{"key":"B8","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1007\/s13304-021-01010-w","article-title":"Changes in surgicaL behaviOurs dUring the COVID-19 pandemic. 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