{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:25:13Z","timestamp":1792027513542,"version":"4.4.0"},"reference-count":8,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T00:00:00Z","timestamp":1711584000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Hypacusia can be caused by various etiologies; however, hearing loss attributed to gouty tophi remains a rare occurrence. This case report presents, for the first time, a bilateral gouty tophi causing hearing impairment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>This report describes a case study involving an 83-year-old Caucasian female patient who presented symptoms of hypacusia, pruritus, and a sensation of pressure in her right ear. A computed tomography scan revealed the presence of non-homogeneous calcified structures in both ears. Following a comprehensive assessment that included pure-tone audiometry and a thorough evaluation of the patient's clinical complaints, a tympanoplasty procedure was initially performed on the right ear. Pathological analysis revealed the presence of gouty tophi. After surgical removal of the tophus, a notable improvement in the patient's hearing threshold was observed. Four months later, a similar surgical intervention was performed on the contralateral ear, achieving a similar positive outcome. The substantial postoperative decrease of bone conduction indicates an inner ear affection by the gout tophi.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Gout tophus in both ears is a very rare but possible cause of hypacusia, even in the absence of a pre-existing diagnosis of systemic gout disease. We report a case of gout tophi in both ears as a rare cause of hearing loss.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2024.1353116","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T04:38:56Z","timestamp":1711600736000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: A rare case of bilateral middle ear tophaceous gout"],"prefix":"10.3389","volume":"11","author":[{"given":"Aybige","family":"Camurdan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conrad","family":"Riemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Brasch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Todt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,3,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"ITC81","DOI":"10.7326\/AITC202012010","article-title":"Hearing loss","volume":"173","author":"Nieman","year":"2020","journal-title":"Ann Intern Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.pop.2013.10.003","article-title":"Hearing loss","volume":"41","author":"Lasak","year":"2014","journal-title":"Prim Care"},{"key":"B3","author":"Gaffo","year":"2019"},{"key":"B4","doi-asserted-by":"publisher","first-page":"238","DOI":"10.4081\/reumatismo.2011.238","article-title":"Clinical features of gout","volume":"63","author":"Grassi","year":"2012","journal-title":"Reumatismo"},{"key":"B5","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.joto.2021.09.001","article-title":"Hearing loss due to urate deposition in the middle ear: a case report and literature review","volume":"17","author":"Hoste","year":"2022","journal-title":"J Otol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1159\/000500514","article-title":"Tophaceous gout of the middle ear: case reports and review of the literature","volume":"24","author":"Saliba","year":"2019","journal-title":"Audiol Neurotol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1097\/mao.0b013e31817fdfde","article-title":"Tophaceous gout of the middle ear","volume":"30","author":"Reineke","year":"2009","journal-title":"Otol Neurotol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"e022854","DOI":"10.1136\/bmjopen-2018-022854","article-title":"Gout and hearing impairment in the elderly: a retrospective cohort study using the US Medicare claims data","volume":"8","author":"Singh","year":"2018","journal-title":"BMJ Open"}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2024.1353116\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T04:39:38Z","timestamp":1711600778000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2024.1353116\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,28]]},"references-count":8,"alternative-id":["10.3389\/fsurg.2024.1353116"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2024.1353116","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,28]]},"article-number":"1353116"}}