{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:34:55Z","timestamp":1753893295285,"version":"3.41.2"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82170066, 82270443, 81670275, 81670443"],"award-info":[{"award-number":["82170066, 82270443, 81670275, 81670443"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>New-onset postoperative atrial fibrillation (POAF) is a common complication after pulmonary thromboendarterectomy (PEA), yet the risk factors and their impact on prognosis remain poorly understood. This study aims to investigate the risk factors associated with new-onset POAF after PEA and elucidate its underlying connection with adverse postoperative outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis included 129 consecutive chronic thromboembolic pulmonary hypertension (CTEPH) patients and 16 sarcoma patients undergoing PEA. Univariate and multivariate analyses were conducted to examine the potential effects of preoperative and intraoperative variables on new-onset POAF following PEA. Propensity score matching (PSM) was then employed to adjust for confounding factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Binary logistic regression revealed that age (odds ratio [OR]\u2009=\u20091.041, 95% confidence interval [CI]\u2009=\u20091.008\u20131.075, <jats:italic>p\u2009=\u2009<\/jats:italic>0.014) and left atrial diameter[LAD] (OR\u2009=\u20091.105, 95% CI\u2009=\u20091.025\u20131.191, <jats:italic>p<\/jats:italic>\u2009=\u20090.009) were independent risk factors for new-onset POAF after PEA. The receiver operating characteristic (ROC) curve indicated that the predictive abilities of age and LAD for new-onset POAF were 0.652 and 0.684, respectively. Patients with new-onset POAF, compared with those without, exhibited a higher incidence of adverse outcomes (in-hospital mortality, acute heart failure, acute kidney insufficiency, reperfusion pulmonary edema). Propensity score matching (PSM) analyses confirmed the results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Advanced age and LAD independently contribute to the risk of new-onset POAF after PEA. Patients with new-onset POAF are more prone to adverse outcomes. Therefore, heightened vigilance and careful monitoring of POAF after PEA are warranted.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fsurg.2024.1380570","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T11:36:11Z","timestamp":1717068971000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["New-onset postoperative atrial fibrillation after pulmonary endarterectomy is associated with adverse outcomes"],"prefix":"10.3389","volume":"11","author":[{"given":"Dingkai","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaohua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanan","family":"Zhen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaopeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueqiang","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhidong","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1801913","DOI":"10.1183\/13993003.01913-2018","article-title":"Haemodynamic definitions and updated clinical classification of pulmonary hypertension","volume":"53","author":"Simonneau","year":"2019","journal-title":"Eur Respir J"},{"key":"B2","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1378\/chest.81.2.151","article-title":"Longterm follow-up of patients with pulmonary thromboembolism","volume":"81","author":"Riedel","year":"1982","journal-title":"Chest"},{"key":"B3","doi-asserted-by":"publisher","first-page":"160121","DOI":"10.1183\/16000617.0121-2016","article-title":"An epidemiological analysis of the burden of chronic thromboembolic pulmonary hypertension in the USA, Europe and Japan","volume":"26","author":"Gall","year":"2017","journal-title":"Eur Respir Rev"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1973","DOI":"10.1161\/CIRCULATIONAHA.110.015008","article-title":"Chronic thromboembolic pulmonary hypertension (CTEPH): results from an international prospective registry","volume":"124","author":"Pepke-Zaba","year":"2011","journal-title":"Circulation"},{"key":"B5","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/S2213-2600(14)70089-X","article-title":"Chronic thromboembolic pulmonary hypertension","volume":"2","author":"Hoeper","year":"2014","journal-title":"Lancet Respir Med"},{"key":"B6","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1111\/resp.13947","article-title":"Characteristics and long-term survival of patients with chronic thromboembolic pulmonary hypertension in China","volume":"26","author":"Deng","year":"2021","journal-title":"Respirology"},{"key":"B7","doi-asserted-by":"publisher","first-page":"144","DOI":"10.2459\/JCM.0000000000000327","article-title":"Pulmonary endarterectomy in the elderly: safety, efficacy and risk factors","volume":"17","author":"Vistarini","year":"2016","journal-title":"J Cardiovasc Med"},{"key":"B8","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1093\/ejcts\/ezw099","article-title":"Outcome after surgical treatment of chronic thromboembolic pulmonary hypertension: dealing with different patient subsets. 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