{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T19:54:06Z","timestamp":1772826846589,"version":"3.50.1"},"reference-count":6,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:00:00Z","timestamp":1745366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>Undifferentiated embryonal sarcoma of the liver (UESL) is an exceedingly rare primary malignant tumor, predominantly affecting children and, to a lesser extent, adults. In adult patients, UESL constitutes a mere 7% of all liver sarcomas. This case report details an instance of hepatic embryonal sarcoma in a 33-year-old female patient who had no significant prior medical history and presented with complaints of abdominal pain. She was hospitalized for surgical intervention. Diagnostic imaging, including CT and MRI scans, disclosed a substantial cystic mass located in the right lobe of the liver. A lumpectomy was performed, and subsequent pathological and histological examinations confirmed the diagnosis of undifferentiated embryonal sarcoma. After surgery, the patient received adjuvant chemotherapy. We are pleased to report that she has remained in complete and sustained remission for the past 3\u2005years.<\/jats:p>","DOI":"10.3389\/fsurg.2025.1481264","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T05:21:47Z","timestamp":1745385707000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Diagnosis and treatment of an undifferentiated embryonal sarcoma of the liver"],"prefix":"10.3389","volume":"12","author":[{"given":"Xiaojiao","family":"Qiu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lexing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,4,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1053\/hupa.2003.44","article-title":"Undifferentiated (embryonal) sarcoma of the liver in middle-aged adults: smooth muscle differentiation determined by immunohistochemistry and electron microscopy","volume":"34","author":"Nishio","year":"2003","journal-title":"Hum Pathol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"311","DOI":"10.4132\/KoreanJPathol.2014.48.4.311","article-title":"Undifferentiated embryonal sarcoma in adult liver","volume":"48","author":"Hong","year":"2014","journal-title":"Korean J Pathol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1002\/1097-0142(197807)42:1%3C336::AID-CNCR2820420151%3E3.0.CO;2-V","article-title":"Undifferentiated (embryonal) sarcoma of the liver: report of 31 cases","volume":"42","author":"Stocker","year":"1978","journal-title":"Cancer"},{"key":"B4","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/S0046-8177(83)80005-7","article-title":"Primary hepatic tumors of childhood","volume":"14","author":"Weinberg","year":"1983","journal-title":"Hum Pathol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"102","DOI":"10.3892\/ol.2020.11963","article-title":"Undifferentiated embryonal sarcoma of the liver in adults: retrospective analysis of a case series and systematic review","volume":"20","author":"Shu","year":"2020","journal-title":"Oncol Lett"},{"key":"B6","doi-asserted-by":"publisher","first-page":"292","DOI":"10.3350\/cmh.2015.0102","article-title":"Undifferentiated embryonal sarcoma of the liver in an adult patient","volume":"22","author":"Lee","year":"2016","journal-title":"Clin Mol Hepatol"}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2025.1481264\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T05:21:49Z","timestamp":1745385709000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2025.1481264\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,23]]},"references-count":6,"alternative-id":["10.3389\/fsurg.2025.1481264"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2025.1481264","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,23]]},"article-number":"1481264"}}