{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:06:14Z","timestamp":1791389174480,"version":"4.3.3"},"reference-count":49,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>Gout manifesting in the spine is a relatively rare occurrence. Involvement of the lumbar spine is more common in cases of spinal gout, while reports of gouty tophi forming within the thoracic spinal canal are exceedingly rare. This article reports a case of incomplete paraplegia caused by gouty tophi in the thoracic spinal canal. The patient, a 56-year-old man, returned to normal after undergoing surgical treatment and was monitored for ten months postoperatively. This case highlights the importance of early diagnosis of spinal gout to prevent the progression of neurological symptoms. Surgical treatment for paraplegia caused by intraspinal tophi can yield favorable clinical outcomes. Increasing awareness of spinal gout and implementing effective uric acid management strategies are essential for preventing the severe consequences associated with this condition.<\/jats:p>","DOI":"10.3389\/fsurg.2025.1708430","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T06:27:02Z","timestamp":1765780022000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Gouty tophi in the thoracic spinal canal with incomplete paraplegia: a case report"],"prefix":"10.3389","volume":"12","author":[{"given":"Chunyu","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juncai","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingzhe","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunpeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.1016\/S0140-6736(21)00569-9","article-title":"Gout","volume":"397","author":"Dalbeth","year":"2021","journal-title":"Lancet"},{"key":"B2","doi-asserted-by":"publisher","first-page":"CD010069","DOI":"10.1002\/14651858.CD010069.pub3","article-title":"Interventions for tophi in gout","volume":"2021","author":"Sriranganathan","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1002\/acr.22585","article-title":"Study for updated gout classification criteria: identification of features to classify gout","volume":"67","author":"Taylor","year":"2015","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"B4","doi-asserted-by":"publisher","first-page":"3697","DOI":"10.1007\/s00586-023-07942-8","article-title":"Patient characteristics, surgical treatment, and outcomes in spinal gout: a systematic review of 315 cases","volume":"32","author":"Harlianto","year":"2023","journal-title":"Eur Spine J"},{"key":"B5","doi-asserted-by":"publisher","first-page":"339","DOI":"10.3389\/fmed.2020.00339","article-title":"The frequency of axial deposition in Korean patients with gout at a tertiary spine center","volume":"7","author":"Jin","year":"2020","journal-title":"Front Med (Lausanne)"},{"key":"B6","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1590\/S0482-50042013000300008","article-title":"Gout in the spine","volume":"53","author":"Hasegawa","year":"2013","journal-title":"Rev Bras Reumatol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1002\/art.1780150209","article-title":"The influence of temperature on the solubility of monosodium urate","volume":"15","author":"Loeb","year":"1972","journal-title":"Arthritis Rheum"},{"key":"B8","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1136\/ard.33.4.313","article-title":"Factors affecting urate solubility in vitro","volume":"33","author":"Kippen","year":"1974","journal-title":"Ann Rheum Dis"},{"key":"B9","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1186\/s12891-015-0762-4","article-title":"Factors influencing the crystallization of monosodium urate: a systematic literature review","volume":"16","author":"Chhana","year":"2015","journal-title":"BMC Musculoskelet Disord"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1136\/ard.2006.063768","article-title":"Are joints affected by gout also affected by osteoarthritis?","volume":"66","author":"Roddy","year":"2007","journal-title":"Ann Rheum Dis"},{"key":"B11","first-page":"1108","article-title":"Association between crystals and cartilage degeneration in the ankle","volume":"35","author":"Muehleman","year":"2008","journal-title":"J Rheumatol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1136\/ard.9.4.282","article-title":"Gout; 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