{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T08:54:05Z","timestamp":1773392045466,"version":"3.50.1"},"reference-count":45,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the feasibility of using patient-specific 3D-printed navigation templates combined with multimodal imaging for low-grade glioma (LGG) surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study was conducted involving 55 patients with supratentorial LGGs. Twenty-seven patients underwent surgery guided by a 3D-printed navigation template with multimodal 3D imaging (3D-printed group), and 28 received conventional neuronavigation-assisted surgery (control group). Perioperative outcomes\u2014including operative time, tumor resection extent, intraoperative navigation usage, complications, and functional recovery\u2014were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The 3D-printed group had significantly shorter operative times (256.2\u2009\u00b1\u20099.8 vs. 271.6\u2009\u00b1\u20098.9\u2005min,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05) and required fewer intraoperative navigation checks (0.2\u2009\u00b1\u20090.4 vs. 2.3\u2009\u00b1\u20091.6,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05). Tumor resection extent was comparable; residual volumes were categorized objectively (&amp;lt;10, 10\u201320, &amp;gt;20\u2005cm\u00b3), with a trend toward lower residuals in the 3D group. Postoperative KPS scores and complication rates were similar between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Combining 3D-printed navigation templates with multimodal imaging enhances surgical precision and efficiency in LGG resection while reducing dependence on costly intraoperative systems. This approach is safe, cost-effective, and especially useful in resource-limited environments.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1687769","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T06:47:28Z","timestamp":1773384448000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["3D-printed navigation templates combined with multimodal imaging assist low-grade glioma surgery: a retrospective cohort study"],"prefix":"10.3389","volume":"13","author":[{"given":"Jun","family":"Qiu","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, The Second People\u2019s Hospital of Yibin","place":["Yibin, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin-Yi","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Second People\u2019s Hospital of Yibin","place":["Yibin, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Second People\u2019s Hospital of Yibin","place":["Yibin, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-Shan","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Second People\u2019s Hospital of Yibin","place":["Yibin, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing-Cheng","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Second People\u2019s Hospital of Yibin","place":["Yibin, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Second People\u2019s Hospital of Yibin","place":["Yibin, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao-Gui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, The Second People\u2019s Hospital of Yibin","place":["Yibin, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu-Jun","family":"Shu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Jinling Hospital","place":["Nanjing, China"]},{"name":"Department of Neurosurgery, Affiliated Jinling Hospital, Medical School of Nanjing University","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1430567","DOI":"10.3389\/fsurg.2024.1430567","article-title":"Neuronavigation in glioma resection: current applications, challenges, and clinical 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