{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T18:10:46Z","timestamp":1770401446755,"version":"3.49.0"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fenestrated and\/or branched endovascular aortic repair (f\/bEVAR) has evolved a reliable alternative to treat complex aortic aneurysms. The aim of this study was to analyze the evolution of f\/bEVAR in a large German vascular department by investigating temporal changes in patient selection, surgical strategies, and clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective cohort study of consecutive patients undergoing f\/bEVAR between 2007 and 2023 at TUM University Hospital in Munich (Klinikum rechts der Isar, Technical University of Munich). To assess for temporal changes, the cohort was divided into three time periods (date of operation: 2007\u20132016; 2017\u20132020; 2021\u20132023). The primary outcome was in-hospital death. Statistical analyses included univariate analyses, Kaplan\u2013Meier survival analyses, and Kruskal\u2013Wallis tests for group comparisons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 176 patients (median age 75 years; 80% male) were included. Over time (\n                      <jats:italic>early phase<\/jats:italic>\n                      vs.\n                      <jats:italic>recent phase<\/jats:italic>\n                      ), an increase in the proportion of octogenarians was observed (14 vs. 31%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.042) and the mean number of incorporated vessels increased from 3.7 to 4.0 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001). Mean operative time decreased from 321 to 241\u2005min (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002) and intraoperative contrast volume was reduced (398 vs. 190\u2005mL;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Length of intensive care unit stay (8.1 vs. 2.7 days;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001) and in-hospital rates of acute kidney injury (16 vs. 4.7%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.034) and respiratory failure (18 vs. 0%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001) declined, while non-significant trends were found for in-hospital mortality (8.8% vs. 1.6%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.062) and the paraplegia rate (8.8% vs. 1.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.062). Longer operating time (per 10\u2005min; OR 1.06; 95% CI 1.02\u20131.11;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) and occurrence of a major adverse event (OR 37.4; 95% CI 4.52\u20134,869;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001) were associated with death until discharge. Kaplan\u2013Meier analyses showed, that patients treated in the\n                      <jats:italic>early phase<\/jats:italic>\n                      had lower survival probability compared to those in the\n                      <jats:italic>recent phase<\/jats:italic>\n                      (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.024).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This retrospective analysis demonstrates a continuous improvement in clinical outcomes associated with f\/bEVAR over the past two decades. The findings underscore the increasing reliability and effectiveness of endovascular treatment approaches.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1743595","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T06:56:15Z","timestamp":1770360975000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Evolution of endovascular repair of complex aortic aneurysms in a German tertiary referral vascular center"],"prefix":"10.3389","volume":"13","author":[{"given":"Yannik","family":"Wanner","sequence":"first","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Munich Aortic Center, TUM University Hospital, Klinikum Rechts der Isar, Technical University of Munich","place":["Munich, Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shamsun","family":"Naher","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Munich Aortic Center, TUM University Hospital, Klinikum Rechts der Isar, Technical University of Munich","place":["Munich, Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Del Pilar","family":"Ortega Carrillo","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Munich Aortic Center, TUM University Hospital, Klinikum Rechts der Isar, Technical University of Munich","place":["Munich, Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Kallmayer","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Munich Aortic Center, TUM University Hospital, Klinikum Rechts der Isar, Technical University of Munich","place":["Munich, Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Kirchhoff","sequence":"additional","affiliation":[{"name":"Department of Vascular and 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