{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T07:02:16Z","timestamp":1780038136922,"version":"3.53.1"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>This study reports a case of scar contracture on the volar side of the left little finger secondary to ruptured ganglion cyst in a 26-year-old female patient, which was misdiagnosed as Dupuytren's disease. The patient had a medical history of Hodgkin's lymphoma and received bleomycin chemotherapy, which may have accelerated the fibrotic process. Intraoperative findings were inconsistent with the preoperative diagnosis, and the final diagnosis was confirmed by pathological examination. Complete surgical resection successfully relieved the contracture. This case suggests that the etiology of subcutaneous scar contracture is complex. Comprehensive evaluation combined with patient medical history, medication history and pathological results is essential to achieve accurate diagnosis.<\/jats:p>","DOI":"10.3389\/fsurg.2026.1744274","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T06:08:57Z","timestamp":1780034937000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Scar contracture caused by ruptured subcutaneous ganglion cyst misdiagnosed as Dupuytren's disease: diagnostic reflections on a rare case"],"prefix":"10.3389","volume":"13","author":[{"given":"Kai","family":"Jiang","sequence":"first","affiliation":[{"name":"The First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine","place":["Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Li","sequence":"additional","affiliation":[{"name":"Orthopaedic Microsurgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine","place":["Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Ma","sequence":"additional","affiliation":[{"name":"Orthopaedic Microsurgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine","place":["Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-zhen","family":"Liang","sequence":"additional","affiliation":[{"name":"The First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine","place":["Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-fa","family":"Rong","sequence":"additional","affiliation":[{"name":"The First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine","place":["Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Orthopaedic Microsurgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine","place":["Shandong, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.4103\/abr.abr_155_21","article-title":"The effect of shock wave therapy on improving the symptoms and function of patients with Dupuytren\u2019s contracture","volume":"11","author":"Taheri","year":"2022","journal-title":"Adv Biomed Res"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5604\/01.3001.0016.0058","article-title":"Dupuytrens disease - whats new: a review","volume":"95","author":"Zyluk","year":"2022","journal-title":"Pol Przegl Chir"},{"key":"B3","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1093\/molbev\/msad130","article-title":"Major genetic risk factors for Dupuytren\u2019s disease are inherited from neandertals","volume":"40","author":"\u00c5gren","year":"2023","journal-title":"Mol Biol Evol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3390\/ijms25136865","article-title":"Biochemical and histological differences between longitudinal and vertical fibres of Dupuytren\u2019s palmar aponeurosis and innovative clinical implications","volume":"25","author":"Fede","year":"2024","journal-title":"Int J Mol Sci"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1007\/s12013-024-01384-9","article-title":"Mechanisms of bleomycin-induced lung fibrosis: a review of therapeutic targets and approaches","volume":"82","author":"Mohammed","year":"2024","journal-title":"Cell Biochem Biophys"},{"key":"B6","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.medcli.2023.09.025","article-title":"Bleomycin-induced flagellate dermatitis in a patient with Hodgkin lymphoma","volume":"162","author":"Danesin","year":"2024","journal-title":"Med Clin"},{"key":"B7","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/S0266-7681(02)00365-0","article-title":"Palmar wrist ganglion: does intervention improve outcome? A prospective study of the natural history and patient-reported treatment outcomes","volume":"28","author":"Dias","year":"2003","journal-title":"J Hand Surg Br"},{"key":"B8","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/S0363-5023(88)80144-8","article-title":"Ganglion cysts and carpal tunnel syndrome","volume":"13","author":"Kerrigan","year":"1988","journal-title":"J Hand Surg Am"},{"key":"B9","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s41038-017-0080-1","article-title":"Current progress in understanding the molecular pathogenesis of burn scar contracture","volume":"5","author":"Tan","year":"2017","journal-title":"Burns Trauma"},{"key":"B10","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1097\/01.PRS.0000101530.33096.5B","article-title":"The effect of myofibroblast on contracture of hypertrophic scar","volume":"113","author":"Shin","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"B11","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1016\/S0221-0363(06)74062-8","article-title":"Ganglion cyst rupture in the retro-femoral fat: a report of two cases","volume":"87","author":"Laborie","year":"2006","journal-title":"J Radiol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.hcl.2016.12.004","article-title":"Biological principles of scar and contracture","volume":"33","author":"Kwan","year":"2017","journal-title":"Hand Clin"},{"key":"B13","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1089\/wound.2012.0393","article-title":"Mechanoregulation of the myofibroblast in wound contraction, scarring, and fibrosis: opportunities for new therapeutic intervention","volume":"2","author":"Van De Water","year":"2013","journal-title":"Adv Wound Care"},{"key":"B14","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1097\/00006534-198105000-00021","article-title":"The etiology of hypertrophic scar contracture: another view","volume":"67","author":"Brody","year":"1981","journal-title":"Plast Reconstr Surg"},{"key":"B15","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1002\/jmr.2719","article-title":"Mechanical and migratory properties of normal, scar, and Dupuytren\u2019s fibroblasts","volume":"31","author":"Babu","year":"2018","journal-title":"J Mol Recognit"},{"key":"B16","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1007\/s004030000180","article-title":"Bleomycin increases steady-state levels of type I collagen, fibronectin and decorin mRNAs in human skin fibroblasts","volume":"292","author":"Yamamoto","year":"2000","journal-title":"Arch Dermatol Res"},{"key":"B17","doi-asserted-by":"publisher","first-page":"a022293","DOI":"10.1101\/cshperspect.a022293","article-title":"TGF-beta1 signaling and tissue fibrosis","volume":"10","author":"Kim","year":"2018","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.mayocp.2018.12.003","article-title":"Bleomycin-induced flagellate dermatitis","volume":"94","author":"Imhof","year":"2019","journal-title":"Mayo Clin Proc"}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2026.1744274\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T06:09:01Z","timestamp":1780034941000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2026.1744274\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,29]]},"references-count":18,"alternative-id":["10.3389\/fsurg.2026.1744274"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2026.1744274","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,29]]},"article-number":"1744274"}}