{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T08:26:45Z","timestamp":1771921605961,"version":"3.50.1"},"reference-count":11,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>Perianal necrotizing fasciitis (PNF) is a life-threatening soft tissue infection with high mortality. Despite the established role of radical debridement, outcomes are often hindered by late diagnosis and suboptimal postoperative care. While negative pressure wound therapy (NPWT) promotes complex wound healing, its synergistic application with radical debridement in PNF requires further validation. We report a case of extensive PNF that demonstrated the limitations of traditional interventions. By utilizing an integrated strategy of extended-incision radical debridement and early NPWT, we achieved rapid infection control and accelerated wound healing. This case suggests that such a combined technical framework can overcome clinical challenges and significantly improve PNF prognosis.<\/jats:p>","DOI":"10.3389\/fsurg.2026.1747876","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T06:47:20Z","timestamp":1771915640000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Negative pressure wound therapy for perianal necrotizing fasciitis: case report and literature review"],"prefix":"10.3389","volume":"13","author":[{"given":"Hao","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Anorectal Center, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Anorectal Center, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahong","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Anorectal Center, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingrui","family":"Liu","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiahui","family":"Chen","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anorectal Center, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Ge","sequence":"additional","affiliation":[{"name":"Nanjing University of Chinese Medicine","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s11934-025-01275-3","article-title":"Modern management of fournier\u2019s gangrene","volume":"26","author":"Kopechek","year":"2025","journal-title":"Curr Urol Rep"},{"key":"B2","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1016\/j.sxmr.2022.05.002","article-title":"Genital reconstruction following fournier\u2019s gangrene","volume":"10","author":"Michael","year":"2022","journal-title":"Sex Med Rev"},{"key":"B3","doi-asserted-by":"publisher","first-page":"S19","DOI":"10.1097\/SAP.0000000000003891","article-title":"Negative pressure wound therapy for chronic wounds","volume":"93","author":"Li","year":"2024","journal-title":"Ann Plast Surg"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1097\/JU.0000000000002960","article-title":"Prodromal fournier\u2019s gangrene: a potential opportunity for early intervention","volume":"208","author":"Koch","year":"2022","journal-title":"J Urol"},{"key":"B5","first-page":"571","article-title":"Management and treatment of fournier\u2019s gangrene. 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