{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:51:10Z","timestamp":1782478270780,"version":"3.54.5"},"reference-count":8,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017957","name":"Health Commission of Guizhou Province","doi-asserted-by":"publisher","award":["GZWKJ2026-289"],"award-info":[{"award-number":["GZWKJ2026-289"]}],"id":[{"id":"10.13039\/100017957","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017957","name":"Health Commission of Guizhou Province","doi-asserted-by":"publisher","award":["GZWKJ2026-292"],"award-info":[{"award-number":["GZWKJ2026-292"]}],"id":[{"id":"10.13039\/100017957","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>\n                    Ectopic thyroid tissue is an uncommon developmental anomaly, and involvement of the hepatobiliary region\u2014particularly near the gallbladder neck or cystic duct\u2014is extremely rare. Such lesions may mimic primary biliary or gallbladder masses, creating diagnostic and therapeutic uncertainty. We report a 50-year-old woman with a 2-year history of intermittent right upper quadrant abdominal pain. Contrast-enhanced CT demonstrated a well-defined hyperdense lesion at the hepatic hilum adjacent to the gallbladder neck, measuring 22\u2009\u00d7\u200914\u2005mm (\u223c80 HU on non-contrast; 119 HU arterial; 104 HU venous), with indistinct borders from the gallbladder. A biliary or gallbladder-associated tumor could not be excluded, and further evaluation with MRI and PET-CT was recommended. The patient declined additional imaging due to financial constraints and strongly requested operative management. Laparoscopic cholecystectomy with\n                    <jats:italic>en bloc<\/jats:italic>\n                    resection of the hilar lesion was performed. Intraoperative frozen-section analysis and final histopathology revealed benign ectopic thyroid tissue composed of mature, well-differentiated thyroid follicles without atypia. Postoperative thyroid ultrasound showed a normal orthotopic thyroid gland. The patient recovered uneventfully and remained symptom-free at follow-up. Ectopic thyroid tissue adjacent to the gallbladder neck is an exceptionally rare cause of a hilar mass. Surgeons should consider this entity in the differential diagnosis of gallbladder neck or porta hepatis lesions of uncertain origin and rely on histopathology to guide appropriate, conservative management.\n                  <\/jats:p>","DOI":"10.3389\/fsurg.2026.1751389","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:36:23Z","timestamp":1782477383000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["A cystic lesion adjacent to the cystic duct diagnosed as ectopic thyroid tissue: a laparoscopic case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Jingnan","family":"Xue","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary Surgery, People\u2019s Hospital of Anshun City","place":["Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohai","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, People\u2019s Hospital of Anshun City","place":["Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longhao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangqin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pathology, People\u2019s Hospital of Anshun City","place":["Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoli","family":"He","sequence":"additional","affiliation":[{"name":"Department of Thyroid and Breast Surgery, People\u2019s Hospital of Anshun City","place":["Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanzi","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Thyroid and Breast Surgery, People\u2019s Hospital of Anshun City","place":["Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, People\u2019s Hospital of Anshun City","place":["Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, People\u2019s Hospital of Anshun City","place":["Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e95027","DOI":"10.7759\/cureus.95027","article-title":"A review of thyroid rests: from embryology to clinical management","volume":"17","author":"Aldawas","year":"2025","journal-title":"Cureus"},{"key":"B2","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.ijsu.2014.05.076","article-title":"Morphological, diagnostic and surgical features of ectopic thyroid gland: a review of literature","volume":"12","author":"Guerra","year":"2014","journal-title":"Int J Surg."},{"key":"B3","doi-asserted-by":"publisher","first-page":"e94823","DOI":"10.7759\/cureus.94823","article-title":"Ectopic thyroid carcinoma presenting as a superior mediastinal cystic mass","volume":"17","author":"Kajihara","year":"2025","journal-title":"Cureus"},{"key":"B4","doi-asserted-by":"publisher","first-page":"e94059","DOI":"10.7759\/cureus.94059","article-title":"Triple-Site ectopic thyroid involving the submandibular, lingual, and infrahyoid regions: a rare case","volume":"17","author":"Tej","year":"2025","journal-title":"Cureus"},{"key":"B5","doi-asserted-by":"publisher","first-page":"45","DOI":"10.3390\/jcdd12020045","article-title":"A rare case of an intracardial ectopic thyroid in the right ventricle","volume":"12","author":"Wei","year":"2025","journal-title":"J Cardiovasc Dev Dis."},{"key":"B6","doi-asserted-by":"publisher","first-page":"2059","DOI":"10.21037\/tp-24-307","article-title":"Biliary atresia with ectopic thyroid in the porta hepatis: a case report and literature review","volume":"13","author":"Zhao","year":"2024","journal-title":"Transl Pediatr"},{"key":"B7","doi-asserted-by":"publisher","first-page":"448","DOI":"10.14309\/ajg.0000000000001040","article-title":"Ectopic thyroid tissue in duodenum-A rare case in a young woman","volume":"116","author":"Liu","year":"2021","journal-title":"Am J Gastroenterol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1148\/radiol.210539","article-title":"Case 306: ectopic thyroid goiter in the porta hepatis","volume":"305","author":"Mamone","year":"2022","journal-title":"Radiology"}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2026.1751389\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:36:23Z","timestamp":1782477383000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2026.1751389\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,26]]},"references-count":8,"alternative-id":["10.3389\/fsurg.2026.1751389"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2026.1751389","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,26]]},"article-number":"1751389"}}