{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:10:29Z","timestamp":1778821829388,"version":"3.51.4"},"reference-count":10,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>Fournier's gangrene (FG) is a rare but life-threatening necrotizing fasciitis of the perineum and genital regions. Rectal cancer perforation is an uncommon cause of FG, and optimal management remains challenging.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report a 62-year-old male with rectal cancer complicated by severe FG secondary to rectal perforation. The patient underwent emergency fecal diversion, repeated extensive perineal debridement combined with vacuum-assisted closure (VAC) therapy, and intensive supportive care. Following infection control and clinical stabilization, definitive surgical management was performed, including laparoscopic abdominoperineal resection and reconstruction of the large perineal defect using a vascularized gracilis muscle flap and a gluteus maximus fascia composite flap. At two-month follow-up, the patient demonstrated complete wound healing, stable colostomy function, and recovery of independent daily activities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case highlights the complexity of managing FG associated with rectal cancer perforation and demonstrates the feasibility of sequential treatment strategies integrating infection control, oncologic resection, and reconstructive surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1790699","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:27:06Z","timestamp":1778819226000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Multidisciplinary collaboration for the treatment of severe necrotizing fasciitis in the perineum caused by rectal cancer perforation"],"prefix":"10.3389","volume":"13","author":[{"given":"Hang","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Burns and Wound Center, The Second Affiliated Hospital, Zhejiang University School of Medicine","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Burns and Wound Center, The Second Affiliated Hospital, Zhejiang University School of Medicine","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqian","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Surgery ICU, The Second Affiliated Hospital, Zhejiang University School of Medicine","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaojun","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery and Oncology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine","place":["Hangzhou, Zhejiang, China"]},{"name":"Center for Medical Research and Innovation in Digestive System Tumors, Ministry of Education","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianwei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery and Oncology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine","place":["Hangzhou, Zhejiang, China"]},{"name":"Center for Medical Research and Innovation in Digestive System Tumors, Ministry of Education","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinlei","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Department, The Second Affiliated Hospital, Zhejiang University School of Medicine","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery and Oncology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine","place":["Hangzhou, Zhejiang, China"]},{"name":"Center for Medical Research and Innovation in Digestive System Tumors, Ministry of Education","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ran","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Surgery ICU, The Second Affiliated Hospital, Zhejiang University School of Medicine","place":["Hangzhou, Zhejiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"4085","DOI":"10.3390\/jcm13144085","article-title":"Fournier\u2019s gangrene surgical reconstruction: a systematic review","volume":"13","author":"Susini","year":"2024","journal-title":"J Clin Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1016\/j.sxmr.2022.05.002","article-title":"Genital reconstruction following Fournier\u2019s gangrene","volume":"10","author":"Michael","year":"2022","journal-title":"Sex Med Rev"},{"key":"B3","doi-asserted-by":"publisher","first-page":"9002","DOI":"10.3748\/wjg.v21.i30.9002","article-title":"Rectal cancer and Fournier\u2019s gangrene\u2014current knowledge and therapeutic options","volume":"21","author":"Bruketa","year":"2015","journal-title":"World J Gastroenterol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"30","DOI":"10.3892\/mco.2024.2728","article-title":"Fournier\u2019s gangrene due to rectal cancer: a case report","volume":"20","author":"Hou","year":"2024","journal-title":"Mol Clin Oncol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.ijid.2019.12.030","article-title":"Fournier\u2019s gangrene mortality: a 17-year systematic review and meta-analysis","volume":"92","author":"El-Qushayri","year":"2020","journal-title":"Int J Infect Dis"},{"key":"B6","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.ijscr.2020.01.040","article-title":"Fournier\u2019s gangrene in a rectal cancer patient","volume":"67","author":"Hyun","year":"2020","journal-title":"Int J Surg Case Rep"},{"key":"B7","doi-asserted-by":"publisher","first-page":"107955","DOI":"10.1016\/j.ijscr.2023.107955","article-title":"Management of Fourniers gangrene secondary to perineal invasion by rectal 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Med"}],"container-title":["Frontiers in Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2026.1790699\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:27:07Z","timestamp":1778819227000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fsurg.2026.1790699\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,15]]},"references-count":10,"alternative-id":["10.3389\/fsurg.2026.1790699"],"URL":"https:\/\/doi.org\/10.3389\/fsurg.2026.1790699","relation":{},"ISSN":["2296-875X"],"issn-type":[{"value":"2296-875X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,15]]},"article-number":"1790699"}}