{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T07:31:00Z","timestamp":1793691060589,"version":"4.5.1"},"reference-count":53,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oncologic quality in colon cancer surgery hinges on achieving adequate longitudinal margins, lymphadenectomy, and mesenteric excision, yet international standards and segment-specific practices remain heterogeneous.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A focused PubMed\/MEDLINE search from inception to October 2025 identified international guidelines, randomized and non-randomized comparative studies, large registries, and meta-analyses addressing: (1) longitudinal resection margins; (2) lymph node (LN) yield and nodal metrics; and (3) complete mesocolic excision (CME) with central vascular ligation (CVL)\/D3 versus standard colectomy in curative-intent colon cancer surgery. The study aimed to delineate current standards in colon cancer resection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mapping studies and guidelines converge on 5\u20137\u2005cm longitudinal margins for most tumors, with extension toward 10\u2005cm in advanced T stage (cT3\u2013cT4 disease) or when arterial geometry indicates a longer at-risk pericolic segment. LN assessment beyond the historical \u226512 minimum improves staging accuracy and survival, with several large datasets suggesting a plateau around 18\u201322 examined nodes. CME\/CVL\/D3 reliably increases nodal yield and specimen quality without excess morbidity in optimized settings and appears to confer an oncologic advantage across stages II\u2013III, with the most consistent survival signal in stage III disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>An oncologically adequate colectomy should aim for: (1) R0 resection with 5\u20137\u2005cm margins, extendable toward 10\u2005cm when dictated by tumor stage or vascular anatomy; (2) mesenteric resection to the feeding-vessel origin targeting 18\u201322 LNs (minimum \u226512), with systematic reporting of tumor deposits and LN ratio; and (3) thoughtful use of CME\/CVL\/D3 embedded within structured training and routine audit of outcomes, particularly for stage III right colon cancers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1831262","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T05:38:21Z","timestamp":1782106701000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Oncologic standards in colon cancer resection: from margins to lymph node yield and mesentery"],"prefix":"10.3389","volume":"13","author":[{"given":"Mariarosaria","family":"Portinaio","sequence":"first","affiliation":[{"name":"Department of General Surgery, Fondazione Poliambulanza Hospital","place":["Brescia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo Alberto","family":"Schena","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Fondazione Poliambulanza Hospital","place":["Brescia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Ammendola","sequence":"additional","affiliation":[{"name":"Operative Unit of Digestive Surgery, University \u201cMagna Grecia\u201d","place":["Catanzaro, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey Yuet Mun","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Upper Gastrointestinal Surgery, Royal North Shore Hospital","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Tejedor","sequence":"additional","affiliation":[{"name":"Colorectal Surgery Unit, University Hospital Gregorio Mara\u00f1\u00f3n","place":["Madrid, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fausto","family":"Rosa","sequence":"additional","affiliation":[{"name":"Universit\u00e0 Cattolica del Sacro Cuore","place":["Rome, Italy"]},{"name":"Department of Emergency and Trauma Surgery, Fondazione Policlinico Universitario A. 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