{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T07:01:25Z","timestamp":1780038085951,"version":"3.53.1"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This meta-analysis evaluates the perioperative safety and comparative efficacy of single-port versus multi-port video-assisted thoracoscopic surgery (VATS) for bullous lung resection in patients with primary spontaneous pneumothorax.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic search of PubMed, Embase, Cochrane Library, and Web of Science was conducted through August 2025 to identify cohort studies comparing single-port (conventional or modified) versus multi-port (double-\/triple-port) VATS. Data synthesis was performed using Stata 17.0 with random-effects models to account for inter-study heterogeneity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirteen cohort studies (1,151 patients) were included. Single-port VATS was associated with significantly reduced hospital stay [mean difference (MD)\u2009=\u20090.246 days; 95% CI, 0.075\u20130.416] and a reduction in postoperative pain (MD\u2009=\u20091.100; 95% CI, 0.528\u20131.671) compared with multi-port VATS. The incidence of chest wall paresthesia was also lower (risk ratio\u2009=\u20090.580; 95% CI, 0.432\u20130.779). No significant differences were observed in operative time, chest tube duration, stapler use, complications, or recurrence. Subgroup analysis showed that the abbreviated hospital stay was primarily driven by conventional single-port techniques, whereas modified techniques showed no significant difference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Single-port VATS for bullous lung resection is associated with accelerated recovery, attenuated postoperative pain, and a lower incidence of neurological sequelae compared to multi-port VATS, without increasing operative time, complication, or recurrence rates. It represents a safe and feasible alternative, although further randomized trials are needed to establish superiority.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1838672","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T06:02:07Z","timestamp":1780034527000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical efficacy and safety of different video-assisted thoracoscopic surgery approaches for bullous lung resection: a systematic review and meta-analysis"],"prefix":"10.3389","volume":"13","author":[{"given":"Ting","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Medicine, Xianyang Central Hospital","place":["Xianyang, Shaanxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaopeng","family":"He","sequence":"additional","affiliation":[{"name":"Department of Respiratory and 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