{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T13:16:03Z","timestamp":1784207763647,"version":"3.55.0"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze the clinical characteristics of atypical subcutaneous nodule-type paragonimiasis in children and accumulate experience in its diagnosis and treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted on the clinical data of 3 pediatric cases with atypical subcutaneous nodule-type paragonimiasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All patients had a clear epidemiological history, significantly elevated peripheral blood eosinophils and positive\n                      <jats:italic>Paragonimus<\/jats:italic>\n                      antibodies. Oral praziquantel achieved excellent therapeutic effects, and surgery could serve as an adjuvant treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Paragonimiasis presents with complex and diverse clinical manifestations, and its clinical symptoms and signs lack specificity. Attention should be paid to taking a detailed epidemiological history; elevated eosinophils and positive\n                      <jats:italic>Paragonimus<\/jats:italic>\n                      antibodies are helpful for diagnosis. Oral praziquantel combined with adjuvant surgical treatment can yield good clinical outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1848773","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:46:15Z","timestamp":1784205975000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Atypical subcutaneous nodule-type paragonimiasis in 3 children: case series"],"prefix":"10.3389","volume":"13","author":[{"given":"Zhaokun","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, The First Affiliated Hospital of China Three Gorges University (Yichang Central People's Hospital)","place":["Yichang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, The First Affiliated Hospital of 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