{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T07:16:22Z","timestamp":1788419782220,"version":"build-2803163510"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Venous thromboembolism (VTE) is a common and potentially serious complication following laparoscopic nephrectomy. Conventional preventive measures are limited by bleeding risk and poor compliance. Electrophysiological stimulation therapy has emerged as a non-invasive approach to improve venous circulation, but its perioperative efficacy remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This prospective, non-randomized controlled study included 108 patients undergoing laparoscopic nephrectomy. Patients were allocated to a control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200957) receiving routine VTE prophylaxis or an observation group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200951) receiving additional electrophysiological stimulation therapy. Venous blood flow velocity, Caprini score, D-dimer levels, and clinical recovery indicators were assessed preoperatively (T0) and before the first ambulation (T1). Change values (\u0394\u2009=\u2009T1\u2212T0) were analyzed. Multivariate regression and correlation analyses were performed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared with the control group, the observation group showed significantly higher postoperative venous blood flow velocities in the popliteal, posterior tibial, and fibular veins (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05). \u0394 analysis demonstrated greater improvements in venous hemodynamics (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05). Hospital stay (6.86\u2009\u00b1\u20092.39 vs. 7.98\u2009\u00b1\u20092.44 days,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.018) and bed rest duration were significantly reduced. Regression analysis identified electrophysiological therapy (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.98,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.018) and improved venous flow (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.42,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.006) as independent predictors of shorter hospitalization. Venous flow improvement was moderately negatively correlated with hospital stay (r\u2009=\u2009\u22120.36 to \u22120.41).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Electrophysiological stimulation therapy was associated with improved venous hemodynamics and postoperative recovery following laparoscopic nephrectomy and may serve as a useful adjunct to routine perioperative thromboprophylaxis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1854870","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T06:41:36Z","timestamp":1788417696000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Electrophysiological stimulation is associated with improved lower-extremity venous hemodynamics and postoperative recovery following 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