{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T15:10:49Z","timestamp":1788793849926,"version":"build-2803163510"},"reference-count":17,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012173","name":"China-Japan Friendship Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012173","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Specimen extraction in massive splenomegaly remains a major challenge in laparoscopic splenectomy. To address this, the Completely Enclosed Laparoscopic Isolation System (CELIS) was utilized to enable contained morcellation without incision enlargement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single-arm retrospective study included 14 patients undergoing CELIS-assisted laparoscopic splenectomy with fully enclosed morcellation under intrabag pneumoperitoneum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All procedures were completed without conversion or incision enlargement. Mean operative time was 182.86\u2009\u00b1\u200952.84 min, with efficient CELIS deployment and morcellation. Postoperative pain was low (VAS 2.64 on day 1), and cosmetic outcomes were favorable. Within this small, single-arm retrospective cohort (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200914), 0\/14 cases of clinically or radiologically detectable splenosis or ectopic splenic implantation were observed during the 5-year follow-up (95% CI: 0.0%\u201323.2%), suggesting the preliminary safety and feasibility of this technique.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This preliminary study suggests that CELIS-assisted contained morcellation is technically feasible for large to massive spleens. The 5-year follow-up provides preliminary observational data regarding the absence of detectable splenosis in this selected cohort, though larger comparative studies are required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1876074","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T11:48:45Z","timestamp":1786448925000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Contained morcellation of the spleen using a completely enclosed laparoscopic isolation system: a 5-year follow-up study on the evaluation of splenosis"],"prefix":"10.3389","volume":"13","author":[{"given":"Chang","family":"Zhou","sequence":"first","affiliation":[{"name":"Chinese Academy of Medical Sciences & Peking Union Medical College","place":["Beijing, China"]},{"name":"Department of Obstetrics and Gynecology, China-Japan Friendship Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhui","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gynecologic Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, China-Japan Friendship Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Chinese Academy of Medical Sciences & Peking Union Medical College","place":["Beijing, China"]},{"name":"Department of Obstetrics and Gynecology, China-Japan Friendship Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, China-Japan Friendship Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiying","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, China-Japan Friendship Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Ling","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, China-Japan Friendship Hospital","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1007\/bf02210877","article-title":"Laparoscopic 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