{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T06:02:48Z","timestamp":1784872968749,"version":"3.55.0"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Giant or recurrent neurofibromas associated with neurofibromatosis type 1 (NF1) may mimic vascular tumors and create large reconstructive defects, particularly in mobile regions. We report a recurrent posterior neck and upper-back neurofibroma with failure of primary grafting and subsequent salvage reconstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 23-year-old woman had previously undergone an aborted operation for a lesion diagnosed as hemangioma; postoperative pathology showed neurofibroma. The recurrent mass was excised along the superficial aspect of the deep fascia with an estimated blood loss of approximately 100\u2005mL, leaving a defect involving about 7% of total body surface area. A split-thickness graft harvested from clinically preserved skin overlying the tumor failed after subgraft seroma formation and Klebsiella pneumoniae infection, with approximately 20% graft take. Salvage treatment consisted of repeat debridement, culture-directed infection control, a 1:3 meshed split-thickness graft from the thigh, negative-pressure wound therapy adapted into separate neck and back dressing zones, and postoperative immobilization. Graft take was complete. At 6 months, no recurrence was detected, neck motion was preserved, the Vancouver Scar Scale score was 3, and the Neck Disability Index score was 5.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case emphasizes accurate diagnosis, careful selection of graft donor skin, adequate wound-bed preparation, infection control, secure graft fixation, and immobilization in a high-mobility region. Dividing the negative-pressure dressing into separate zones was a practical modification for this wound rather than a novel reconstructive principle, and broader recommendations cannot be made from a single case.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1876161","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T05:35:26Z","timestamp":1784871326000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Recurrent giant neurofibroma of the posterior neck and upper back with failed primary grafting and salvage reconstruction: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Bo","family":"Zhou","sequence":"first","affiliation":[{"name":"Yichang Central People's Hospital","place":["Yichang, China"]},{"name":"The First College of Clinical Medical Science, China Three Gorges University","place":["Yichang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Liu","sequence":"additional","affiliation":[{"name":"Yichang Central People's Hospital","place":["Yichang, China"]},{"name":"The First College of Clinical Medical Science, China Three Gorges University","place":["Yichang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyao","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Burn and Plastic Surgery, Beihai People's Hospital, the Ninth Affiliated Hospital of Guangxi Medical University, Beihai","place":["Guangxi Zhuang Autonomous Region, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1038\/s41436-021-01170-5","article-title":"Revised diagnostic criteria for neurofibromatosis type 1 and legius syndrome: an international consensus 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