{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T06:05:28Z","timestamp":1784786728152,"version":"3.55.0"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the clinical efficacy of a modified soft brace incorporating a Silver Sulfadiazine (SSD) oil-based dressing in improving wound healing and home care quality following hand scar contracture release surgery in patients with RDEB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Thirty-five RDEB patients (aged 8\u201321 years) who underwent hand contracture release between 2017 and 2023 were assigned to Traditional (Vaseline gauze\u2009+\u2009brace,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200917) or Modified (SSD dressing\u2009+\u2009brace,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200918) groups. Perioperative outcomes, wound healing duration, compliance (RHCS), and recurrence-free survival were compared.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline characteristics were comparable. Compared to the Traditional Group, the Modified Group had significantly fewer dressing changes (2.33\u2009\u00b1\u20090.49 vs. 4.18\u2009\u00b1\u20090.73,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001), shorter healing duration (23.33\u2009\u00b1\u20093.40 vs. 36.24\u2009\u00b1\u20095.09 days,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001), lower epithelial stripping rate (11.1% vs. 64.7%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20091.6E-3), and no refractory wounds. The Modified Group also showed higher RHCS total scores (84.94\u2009\u00b1\u20099.62 vs. 46.12\u2009\u00b1\u200919.12,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001) and fewer spontaneous nocturnal blisters (11.1% vs. 64.7%). Univariable Cox regression indicated the modified regimen was associated with delayed recurrence. Kaplan\u2013Meier analysis showed delayed recurrence in the Modified Group by log-rank test (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.03), and univariable Cox analysis yielded HR 0.39, 95% CI 0.16\u20130.95, albeit with wide confidence intervals and limited late-term power.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this retrospective cohort, the SSD-containing non-adherent dressing used with a soft brace was associated with fewer dressing changes, less dressing-related trauma, and better reported tolerance. Prospective controlled studies with validated functional and compliance outcomes are required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1877597","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T05:37:35Z","timestamp":1784785055000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of modified SSD soft brace on surgical outcomes and wound healing duration following hand scar contracture release in RDEB patients"],"prefix":"10.3389","volume":"13","author":[{"given":"Teng","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, The Second Affiliated Hospital of Zhengzhou University","place":["Zhengzhou, Henan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong","family":"Wu","sequence":"additional","affiliation":[{"name":"The Fifth Clinical Medical College of Henan University of Chinese Medicine (Zhengzhou People\u2019s Hospital)","place":["Zhengzhou, Henan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhe","family":"Jiao","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, The Second Affiliated Hospital of Zhengzhou University","place":["Zhengzhou, Henan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e231287","DOI":"10.1136\/bcr-2019-231287","article-title":"Dystrophic calcinosis cutis in autosomal recessive dystrophic epidermolysis bullosa","volume":"12","author":"Bhari","year":"2019","journal-title":"BMJ Case Rep"},{"key":"B2","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1684\/ejd.2010.1247","article-title":"Mild recessive dystrophic epidermolysis bullosa associated with two compound heterozygous COL7A1 mutations","volume":"21","author":"Von 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