{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T06:10:17Z","timestamp":1783923017505,"version":"3.55.0"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Benign prostatic hyperplasia (BPH) is a common condition in aging men that significantly impacts quality of life. This study aimed to compare the perioperative outcomes and short-term efficacy of holmium laser enucleation of the prostate (HoLEP) vs. transurethral resection of the prostate (TURP) in patients with symptomatic BPH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We retrospectively analyzed data from 176 patients who underwent surgical treatment for BPH at our institution between January 2019 and December 2024. Patients were divided into two groups: HoLEP (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200992) and TURP (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200984). Baseline characteristics, operative parameters, postoperative complications, and functional outcomes in 6-month after surgery were compared between the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline demographics and prostate volume were similar between the two groups. The HoLEP group showed significantly shorter operation time (58.26\u2009\u00b1\u200920.11\u2005min vs. 84.17\u2009\u00b1\u200936.80\u2005min,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001), shorter catheterization time (5.37\u2009\u00b1\u20091.45 vs. 6.27\u2009\u00b1\u20091.47 days,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001), and reduced hospital stay (7.33\u2009\u00b1\u20093.12 vs. 13.61\u2009\u00b1\u20094.14 days,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001). Both groups demonstrated significant improvement in functional outcomes, but HoLEP had better international prostate symptom score, higher Qmax, (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05). HoLEP had lower urinary tract irritation (22.62% vs. 42.86%) and erectile dysfunction (16.67% vs. 29.76%, both\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HoLEP is a safe and effective alternative to TURP for BPH, offering advantages in perioperative safety and early recovery. It may be particularly beneficial in patients with large prostates or higher bleeding risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1891814","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T05:33:47Z","timestamp":1783920827000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["A retrospective study comparing holmium Laser enucleation vs. transurethral resection for the treatment of benign prostatic hyperplasia"],"prefix":"10.3389","volume":"13","author":[{"given":"Zhikai","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Urology, Dongyang People\u2019s Hospital","place":["Jinhua, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongkai","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Urology, Dongyang People\u2019s Hospital","place":["Jinhua, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongjie","family":"Tao","sequence":"additional","affiliation":[{"name":"Department of Urology, Pinghu Traditional Chinese Medicine Hospital","place":["Jiaxing, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/j.medcli.2024.04.014","article-title":"Benign prostatic hyperplasia","volume":"163","author":"Infante Hernandez","year":"2024","journal-title":"Med Clin (Barc)"},{"key":"B2","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1097\/JU.0000000000002183","article-title":"Management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: aUA GUIDELINE PART I-initial work-up and medical management","volume":"206","author":"Lerner","year":"2021","journal-title":"J 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