{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:22:33Z","timestamp":1787736153633,"version":"build-2784847793"},"reference-count":17,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Evaluate the efficacy and safety of pneumonectomy in the treatment of destroyed lung caused by benign diseases, and identify the risk factors for postoperative complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed 158 patients with destroyed lung caused by benign diseases who underwent pneumonectomy in a single center from January 2014 to December 2024. Cases were assigned to tuberculosis (TB) group and non-tuberculosis (non-TB) group. Clinical characteristics and postoperative complications were analyzed and compared between groups. Univariate and multivariate analyses were performed to investigate the risk factors of pneumonectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 125 TB and 33 non-TB patients were included. All patients with preoperative hemoptysis recovered after surgery. Major postoperative complications were observed in 32 patients (20.3%), and perioperative deaths were noted in three patients (1.9%), who were from the TB group. The TB group had a longer duration of surgery and length of stay in the intensive care unit (ICU), a higher proportion of diabetes and postoperative complications (24.0% vs. 6.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.027) than the non-TB group. Multivariate logistic analyses indicated diabetes [odds ratio [OR]: 4.680; 95% con\ufb01dence interval [CI]: 1.578\u201313.881;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005] and duration of surgery (OR: 1.005; 95% CI: 1.001\u20131.010;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.036) were the independent risk factors of postoperative complications of pneumonectomy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pneumonectomy is effective for destroyed lung caused by benign diseases. Patients with TB destroyed lung have a higher risk of postoperative complications. Controlling perioperative blood glucose and reducing duration of surgery may reduce the risk of perioperative complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1907176","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:55:54Z","timestamp":1787734554000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comprehensive analysis of prognostic factors and clinical implications of pneumonectomy for destroyed lung"],"prefix":"10.3389","volume":"13","author":[{"given":"Shanbo","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Xinjiang Uygur Autonomous Region Sixth People\u2019s Hospital","place":["Urumqi, Xinjiang Uygur Autonomous Region, China"]},{"name":"Department of Thoracic Surgery, Fudan University Shanghai Cancer Center","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akbar","family":"Anwar","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Xinjiang Uygur Autonomous Region Sixth People\u2019s Hospital","place":["Urumqi, Xinjiang Uygur Autonomous Region, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wancheng","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Xinjiang Uygur Autonomous Region Sixth People\u2019s Hospital","place":["Urumqi, Xinjiang Uygur Autonomous Region, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaogang","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Xinjiang Uygur Autonomous Region Sixth People\u2019s Hospital","place":["Urumqi, Xinjiang Uygur Autonomous Region, 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