{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:22:01Z","timestamp":1787736121206,"version":"build-2784847793"},"reference-count":16,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Segmentectomy for non-small cell lung cancer (NSCLC) is increasingly performed for small-sized lesions. However, prognostic factors associated with poor outcomes after this lung-sparing oncologic surgery remain uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a single-center retrospective study including 100 consecutive patients who underwent single or multiple segmentectomies for NSCLC in real-world practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In univariate analyses, compromise segmentectomy (HR 3.52;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005), complex segmentectomy (HR 2.56;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.020), SUVmax\u2009\u2265\u20096 (HR 2.86;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.017), and thoracotomy (HR 2.62;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.020) were associated with worse overall survival. In multivariable analysis, compromise segmentectomy remained associated with worse overall survival (HR 3.47;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.026). Regarding recurrence, thoracotomy was associated with poorer disease-free survival (HR 2.77;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this real-world cohort, compromise segmentectomy identified a high-risk subgroup with impaired overall survival, probably reflecting baseline frailty and comorbidity rather than a clearly demonstrated increase in recurrence. These findings support careful preoperative selection and counseling of patients considered for lung-sparing resection outside standard indications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fsurg.2026.1923394","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:51:35Z","timestamp":1787734295000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Current real-life survival after segmentectomy for lung cancer"],"prefix":"10.3389","volume":"13","author":[{"given":"Xavier","family":"Cansouline","sequence":"first","affiliation":[{"name":"Thoracic Surgery Department, Tours University Hospital","place":["Tours, France"]},{"name":"N2C UMR 1069, University of Tours, INSERM","place":["Tours, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoul-Khadry","family":"Gassama","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Tours University Hospital","place":["Tours, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelhakim","family":"Elmraki","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Tours University Hospital","place":["Tours, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9atrice","family":"Lipan","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Tours University Hospital","place":["Tours, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Sizaret","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tours University Hospital","place":["Tours, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Carmier","sequence":"additional","affiliation":[{"name":"Department of Pneumology, Tours University Hospital","place":["Tours, 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