{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T06:09:29Z","timestamp":1789711769719,"version":"4.0.1"},"reference-count":10,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Surg."],"abstract":"<jats:p>The management of peritoneal metastases in young patients with ovarian cancer demands a delicate balance between oncological radicality and quality of life. We present the case of a 34-year-old woman with a final pathological diagnosis of primary advanced-stage (FIGO IIIC) low-grade serous ovarian carcinoma (LGSC) of the left ovary, with metastases to the sigmoid colon, pelvic peritoneum, vesical peritoneum, diaphragm, and omental surface. The diagnosis was confirmed by comprehensive immunohistochemistry (PAX8+, WT1+, ER+, PR+, CA125+, p53 wild-type) and complete histopathological examination. To strictly comply with the \u201cno-touch\u201d isolation principle while maximizing the advantages of minimally invasive surgery, we successfully performed a novel dual single-port laparoscopic cytoreductive procedure. The operation encompassed anterior resection, left salpingo-oophorectomy, omentectomy, and peritonectomy, all accomplished through two discrete 4\u20135\u202fcm single-port incisions, Each platform housed three channels: one for the camera and two for working instruments, facilitating complex multivisceral and peritoneal resections. Complete macroscopic cytoreduction (R0) was achieved, with negative resection margins and only one positive lymph node among three harvested.This case demonstrates the technical feasibility and short-term safety of this innovative approach in a carefully selected patient with advanced ovarian cancer and peritoneal dissemination. However, the short follow-up period is a major limitation, and long-term oncological equivalence or superiority over standard approaches cannot be claimed. The purported advantages regarding reduced tumor manipulation, lower port-site metastasis risk, and superior recovery remain hypothetical and require validation in larger studies. We are continuing surveillance to assess longer-term outcomes.<\/jats:p>","DOI":"10.3389\/fsurg.2026.1938536","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T05:38:15Z","timestamp":1789709895000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Dual single-port laparoscopic surgery for metastatic low-grade serous ovarian carcinoma: a case report of an innovative minimally invasive approach adhering to no-touch isolation technique"],"prefix":"10.3389","volume":"13","author":[{"given":"Xiaoqing","family":"Qing","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Nursing, The Second Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongqin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Nursing, The First Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21654","article-title":"Cancer statistics, 2021","volume":"71","author":"Siegel","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.2353\/ajpath.2010.100105","article-title":"Ovarian cancer development and metastasis","volume":"177","author":"Lengyel","year":"2010","journal-title":"Am J Pathol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"106678","DOI":"10.1016\/j.ijsu.2022.106678","article-title":"Laparoscopic versus open gastrectomy for gastric cancer: a systematic review and meta-analysis of randomized controlled trials","volume":"102","author":"Lou","year":"2022","journal-title":"Int J Surg"},{"key":"B4","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1007\/s00595-016-1346-0","article-title":"Port-site metastasis after laparoscopic surgery for gastrointestinal cancer","volume":"47","author":"Emoto","year":"2017","journal-title":"Surg Today"},{"key":"B5","doi-asserted-by":"publisher","first-page":"101972","DOI":"10.1016\/j.suronc.2023.101972","article-title":"Influence of the no-touch isolation technique on oncologic outcomes for patients with colon cancer undergoing curative surgery: a systematic review and meta-analysis","volume":"50","author":"Ishizuka","year":"2023","journal-title":"Surg Oncol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.jclinepi.2017.04.026","article-title":"CARE Guidelines for case reports: explanation and elaboration document","volume":"89","author":"Riley","year":"2017","journal-title":"J Clin Epidemiol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1038\/s41572-021-00326-6","article-title":"Primary and metastatic peritoneal surface malignancies","volume":"7","author":"Cort\u00e9s-Guiral","year":"2021","journal-title":"Nat Rev Dis Primers"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1895","DOI":"10.1056\/NEJMoa1806395","article-title":"Minimally invasive versus abdominal radical hysterectomy for cervical cancer","volume":"379","author":"Ramirez","year":"2018","journal-title":"N Engl J Med"},{"key":"B9","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/j.clnu.2012.08.013","article-title":"Enhanced recovery after surgery society. 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