{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T05:08:33Z","timestamp":1776834513769,"version":"3.51.2"},"reference-count":50,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Syst. Biol."],"abstract":"<jats:p>\n                    Fritillaria taipaiensis: a medicinal plant of the Liliaceae family endemic to the Qinling Mountains and southern regions of China, is renowned for its therapeutic properties in relieving cough and moistening the lungs. Despite growing interest in the organellar genomes of related species, the mitochondrial genome (mitogenome) of\n                    <jats:italic>F. taipaiensis<\/jats:italic>\n                    has remained uncharacterized. In this study, we successfully assembled and annotated the complete mitogenome of\n                    <jats:italic>F. taipaiensis<\/jats:italic>\n                    using a combination of Illumina and Nanopore technologies. The mitogenome consisted of 23 circular chromosomes with a total length of 847,160\u00a0bp and contained 49 annotated genes, including 34 protein-coding genes (PCGs), 12 transfer RNA (tRNA) genes, and 3 ribosomal RNA (rRNA) genes. Codon usage analysis revealed a strong bias toward A- and U-ending codons. Additionally, we identified 178 simple sequence repeats (SSRs) and 127 dispersed repeats. We also detected ten chloroplast-derived DNA fragments transferred to the mitogenome, most of which involved tRNA genes. A total of 488 RNA editing events were predicted in PCGs, all involving C-to-U conversions. Phylogenetic analysis based on 21 representative plant mitogenomes placed\n                    <jats:italic>F. taipaiensis<\/jats:italic>\n                    in a position congruent with its traditional taxonomic classification. These findings enhance our understanding of the mitogenome architecture and evolutionary dynamics of\n                    <jats:italic>F. taipaiensis<\/jats:italic>\n                    and provide valuable genomic resources for future studies in conservation biology, population genetics, and comparative genomics within the\n                    <jats:italic>Fritillaria<\/jats:italic>\n                    genus.\n                  <\/jats:p>","DOI":"10.3389\/fsysb.2026.1708877","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T04:34:32Z","timestamp":1776832472000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Structure and multipartite genome architecture of the mitochondrial genome in the endangered medicinal plant Fritillaria taipaiensis P. Y. Li"],"prefix":"10.3389","volume":"6","author":[{"given":"De","family":"Xu","sequence":"first","affiliation":[{"name":"Institute of Chinese Materia Medica, Dazhou Academy of Agricultural Sciences","place":["Dazhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingtao","family":"Liu","sequence":"additional","affiliation":[{"name":"Dazhou Key Laboratory of Agricultural Resources Development and Ecological Conservation in Daba Mountain, Sichuan University of Arts and Science","place":["Dazhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Huang","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica, Dazhou Academy of Agricultural Sciences","place":["Dazhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qianqian","family":"Ma","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica, Dazhou Academy of Agricultural Sciences","place":["Dazhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica, Dazhou Academy of Agricultural Sciences","place":["Dazhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhou","family":"Xie","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica, Dazhou Academy of Agricultural Sciences","place":["Dazhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue","family":"Liu","sequence":"additional","affiliation":[{"name":"Chongqing Key Laboratory of Traditional Chinese Medicine Resource, Endangered Medicinal Breeding National Engineering Laboratory, Chongqing Academy of Chinese Materia Medica","place":["Chongqing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Fu","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica, Dazhou Academy of Agricultural Sciences","place":["Dazhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"5040598","DOI":"10.1155\/2016\/5040598","article-title":"Analysis of the complete mitochondrial genome sequence of the diploid cotton Gossypium raimondii by comparative genomics approaches","volume":"2016","author":"Bi","year":"2016","journal-title":"BioMed Research International"},{"key":"B2","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1146\/annurev.genet.35.102401.090231","article-title":"The inheritance of genes in mitochondria and chloroplasts: laws, mechanisms, and models","volume":"35","author":"Birky","year":"2001","journal-title":"Annu. 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