{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:43:13Z","timestamp":1770219793987,"version":"3.49.0"},"reference-count":15,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"DOI":"10.3389\/fvets.2017.00173","type":"journal-article","created":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T04:29:05Z","timestamp":1508214545000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Congenital Myasthenic Syndrome in a Mixed Breed Dog"],"prefix":"10.3389","volume":"4","author":[{"given":"Theresa J.","family":"Blakey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer R.","family":"Michaels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling T.","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy J.","family":"Hodshon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. Diane","family":"Shelton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2017,10,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1111\/j.1939-1676.2005.tb02789.x","article-title":"Congenital myasthenia gravis in smooth-haired miniature dachshund dogs","volume":"19","author":"Dickinson","year":"2005","journal-title":"J Vet Intern Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1016\/j.nmd.2015.09.005","article-title":"A CHRNE frameshift mutation causes congenital myasthenic syndrome in young Jack Russell Terriers","volume":"25","author":"Rinz","year":"2015","journal-title":"Neuromuscul Disord"},{"key":"B3","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.nmd.2016.03.002","article-title":"Myasthenia gravis and congenital myasthenic syndromes in dogs and cats: a history a mini-review","volume":"26","author":"Shelton","year":"2016","journal-title":"Neuromuscul Disord"},{"key":"B4","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1016\/S1474-4422(14)70201-7","article-title":"Congenital myasthenic syndromes: pathogenesis, diagnosis, and treatment","volume":"14","author":"Engel","year":"2015","journal-title":"Lancet Neurol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e106425","DOI":"10.1371\/journal.pone.0106425","article-title":"A COLQ missense mutation in Labrador retrievers having congenital myasthenic syndrome","volume":"9","author":"Rinz","year":"2014","journal-title":"PLoS One"},{"key":"B6","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1093\/jhered\/esm026","article-title":"Identification of a mutation in the CHAT gene of old Danish pointing dogs affected with congenital myasthenic syndrome","volume":"98","author":"Proschowsky","year":"2007","journal-title":"J Hered"},{"key":"B7","doi-asserted-by":"crossref","first-page":"694","DOI":"10.2460\/javma.1983.182.07.694","article-title":"Congenital myasthenia gravis in 13 smooth fox terriers","volume":"182","author":"Miller","year":"1983","journal-title":"J Am Vet Med Assoc"},{"key":"B8","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/BF03548072","article-title":"Congenital myasthenic syndrome in the dog breed Gammel Dansk Honsehund: clinical, electrophysiological, pharmacological and immunological comparison with acquired myasthenia gravis","volume":"30","author":"Flagstad","year":"1989","journal-title":"Acta Vet Scand"},{"key":"B9","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/S0195-5616(03)00085-8","article-title":"Myasthenia gravis and disorders of neuromuscular transmission","volume":"32","author":"Shelton","year":"2002","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"B10","first-page":"135","article-title":"A myasthenic-like syndrome in young related mongrel dogs","volume":"3","author":"Van Ham","year":"1992","journal-title":"Prog Vet Neurol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e0137019","DOI":"10.1371\/journal.pone.0137019","article-title":"A COLQ missense mutation in Sphynx and Devon Rex cats with congenital myasthenic syndrome","volume":"10","author":"Abitbol","year":"2015","journal-title":"PLoS One"},{"key":"B12","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1111\/age.12350","article-title":"COLQ variant associated with Devon Rex and Sphynx feline hereditary myopathy","volume":"46","author":"Gandolfi","year":"2015","journal-title":"Anim Genet"},{"key":"B13","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s10048-002-0134-8","article-title":"Congenital myasthenia in Brahman calves caused by homozygosity for a CHRNE truncating mutation","volume":"4","author":"Kraner","year":"2002","journal-title":"Neurogenetics"},{"key":"B14","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1111\/j.1939-1676.1997.tb00073.x","article-title":"Clinical forms of acquired myasthenia gravis in dogs: 25 cases (1988\u20131995)","volume":"11","author":"Dewey","year":"1997","journal-title":"J Vet Intern Med"},{"key":"B15","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1111\/j.1748-5827.1980.tb01259.x","article-title":"Autoimmune form of myasthenia gravis in a juvenile Yorkshire Terrier x Jack Russell Terrier hybrid contrasted with congenital (non-autoimmune) myasthenia gravis of the Jack Russell","volume":"21","author":"Palmer","year":"1980","journal-title":"J Small Anim Pract"}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fvets.2017.00173\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T14:39:54Z","timestamp":1750948794000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fvets.2017.00173\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,17]]},"references-count":15,"alternative-id":["10.3389\/fvets.2017.00173"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2017.00173","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,17]]},"article-number":"173"}}