{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:20:08Z","timestamp":1759335608404,"version":"3.41.2"},"reference-count":62,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T00:00:00Z","timestamp":1576540800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"DOI":"10.3389\/fvets.2019.00464","type":"journal-article","created":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T05:38:50Z","timestamp":1576561130000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Mandibular Carnassial Tooth Malformations in 6 Dogs\u2014Micro-Computed Tomography and Histology Findings"],"prefix":"10.3389","volume":"6","author":[{"given":"Kevin K.","family":"Ng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacy","family":"Rine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eunju","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadine","family":"Fiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Porter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Fink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago","family":"Peralta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,12,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"65","DOI":"10.2754\/avb200170010065","article-title":"Teeth abnormalities in the dog","volume":"70","author":"Pavlica","year":"2001","journal-title":"Acta Vet Brno"},{"key":"B2","doi-asserted-by":"publisher","first-page":"9","DOI":"10.3389\/fvets.2016.00009","article-title":"Developmental structural tooth defects in dogs \u2013 experience from veterinary dental referral practice and review of the literature","volume":"3","author":"Boy","year":"2016","journal-title":"Front Vet Sci"},{"key":"B3","first-page":"54","article-title":"Abnormalities of teeth","author":"Neville","year":"2009"},{"key":"B4","doi-asserted-by":"publisher","first-page":"23","DOI":"10.5326\/JAAHA-MS-5830","article-title":"Assessment of dental abnormalities by full-mouth radiography in small breed dogs","volume":"49","author":"Kim","year":"2013","journal-title":"J Am Anim Hosp Assoc"},{"key":"B5","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1136\/vr.92.5.115","article-title":"A case of enamel pearls in a dog","volume":"92","author":"Schneck","year":"1973","journal-title":"Vet Rec"},{"key":"B6","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1177\/089875640101800103","article-title":"Treatment of mandibular first molar teeth with endodontic-periodontal lesions in a dog","volume":"18","author":"Niemiec","year":"2001","journal-title":"J Vet Dent"},{"key":"B7","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1177\/089875640502200103","article-title":"Dens invaginatus of the mandibular first molars in a dog","volume":"22","author":"Stein","year":"2005","journal-title":"J Vet Dent"},{"key":"B8","first-page":"201","article-title":"Dens invaginatus bilateral em primeiro molar mandibular em c\u00e3o","volume":"7","author":"Da Roza","year":"2006","journal-title":"Ci\u00ean Anim Brasil"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.2460\/javma.237.11.1251","article-title":"Diagnostic imaging in veterinary dental practice. Dens invaginatus leading to arrested maturation of the right and left mandibular first molar teeth","volume":"237","author":"Duncan","year":"2010","journal-title":"J Am Vet Med Assoc"},{"key":"B10","doi-asserted-by":"publisher","first-page":"299","DOI":"10.2460\/javma.246.3.299","article-title":"Diagnostic imaging in veterinary dental practice. Persistent deciduous teeth","volume":"246","author":"Hiscox","year":"2015","journal-title":"J Am Vet Med Assoc"},{"key":"B11","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1177\/030098588602300318","article-title":"Dental dysplasia in two young uremic dogs","volume":"23","author":"Dubielzig","year":"1986","journal-title":"Vet Pathol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1111\/j.1365-2591.2008.01468.x","article-title":"Dens invaginatus. Part 1: classification, prevalence and aetiology","volume":"41","author":"Alani","year":"2008","journal-title":"Int Endod J"},{"key":"B13","doi-asserted-by":"publisher","first-page":"e218","DOI":"10.4317\/medoral.17475","article-title":"Evaluation of enamel pearls by cone-beam computed tomography (CBCT)","volume":"17","author":"Akg\u00fcl","year":"","journal-title":"Med Oral Patol Oral Cir Bucal. ("},{"key":"B14","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1053\/svms.2000.21042","article-title":"How to obtain and interpret periodontal radiographs in dogs","volume":"15","author":"Tsugawa","year":"2000","journal-title":"Clin Tech Small Animl Pract"},{"key":"B15","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1111\/j.1600-0714.1982.tb00172.x","article-title":"A method for the study of undecalcified bones and teeth with attached soft tissues. The S\u00e4ge-Schliff (sawing and grinding) technique","volume":"11","author":"Donath","year":"1982","journal-title":"J Oral Pathol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/0030-4220(92)90218-F","article-title":"The cutting-grinding technique for histologic preparation of undecalcified bone and bone-anchored implants: improvements in instrumentation and procedures","volume":"74","author":"Rohrer","year":"1992","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"B17","first-page":"31","article-title":"An improved method for preparing histological sections of metallic implants","volume":"1","author":"Maniatopoulos","year":"1986","journal-title":"Int J Oral Maxillofac Implants"},{"key":"B18","first-page":"70","article-title":"Development of the tooth and its supporting tissues","volume-title":"Ten Cate's Oral Histology: Development, Structure, and Function","author":"Nanci","year":"2013"},{"key":"B19","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1177\/089875641002700204","article-title":"Regional odontodysplasia in a juvenile dog","volume":"27","author":"Schamberger","year":"2010","journal-title":"J Vet Dent"},{"key":"B20","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1177\/089875641002700406","article-title":"Multifocal odontoblastic dysplasia in a dog","volume":"27","author":"Smithson","year":"2010","journal-title":"J Vet Dent"},{"key":"B21","first-page":"55","article-title":"Ground sections of teeth with particular reference to enamel","volume":"34","author":"Allison","year":"1977","journal-title":"Med Lab Sci"},{"key":"B22","first-page":"122","article-title":"Enamel: composition, formation, and structure","volume-title":"Ten Cate's Oral Histology: Development, Structure, and Function","author":"Nanci","year":"2012"},{"key":"B23","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1038\/sj.bdj.4804912","article-title":"Developing dens invaginatus (dens in dente). A quantitative microradiographic study and a reconsideration of the histogenesis of this condition","volume":"153","author":"Beynon","year":"1982","journal-title":"Br Dent J"},{"key":"B24","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1111\/j.1600-9657.1993.tb00273.x","article-title":"Dens invaginatus: a histological study of undemineralized material","volume":"9","author":"Piattelli","year":"1993","journal-title":"Endod Dent Traumatol"},{"key":"B25","doi-asserted-by":"publisher","first-page":"ZJ03","DOI":"10.7860\/JCDR\/2017\/26493.9800","article-title":"Light microscopic features of type II dens invaginatus in a deciduous mandibular molar","volume":"11","author":"Pandiar","year":"2017","journal-title":"J Clin Diagn Res"},{"key":"B26","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.joen.2006.06.010","article-title":"Unusual variant of type 3 dens invaginatus in a maxillary canine: a rare case report","volume":"33","author":"\u0160tamfelj","year":"2007","journal-title":"J Endod."},{"key":"B27","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1016\/S1079-2104(96)80317-9","article-title":"Double dens in dente with a central cusp and multituberculism in bilateral maxillary supernumerary central incisors: report of a case","volume":"82","author":"Noikura","year":"1996","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"B28","doi-asserted-by":"publisher","first-page":"150","DOI":"10.2174\/1874210601105010150","article-title":"A dilated odontoma in the second molar region of the mandible","volume":"5","author":"Matsusue","year":"2011","journal-title":"Open Dent J"},{"key":"B29","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1177\/089875640902600407","article-title":"Enamel defects in standard poodle dogs in Sweden","volume":"26","author":"Mannerfelt","year":"2009","journal-title":"J Vet Dent"},{"key":"B30","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1016\/0030-4220(57)90077-4","article-title":"Dens invaginatus (dilated composite odontome). I. Variations of the invagination process and associated anterior crown forms","volume":"10","author":"Oehlers","year":"1957","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1016\/S0030-4220(57)80030-9","article-title":"Dens invaginatus (dilated composite odontome). II. Associated posterior crown forms and pathogenesis","volume":"10","author":"Oehlers","year":"1957","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1016\/0030-4220(58)90278-0","article-title":"The radicular variety of dens invaginatus","volume":"11","author":"Oehlers","year":"1958","journal-title":"Oral Surg Oral Med Oral Pathol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1111\/j.1365-2591.2008.01469.x","article-title":"Dens invaginatus. Part 2: clinical, radiographic features and management options","volume":"41","author":"Bishop","year":"2008","journal-title":"Int Endod J"},{"key":"B34","first-page":"582","article-title":"Dental anomalies","volume-title":"Oral Radiology Principles and Interpretation","author":"Lam","year":"2014"},{"key":"B35","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/0030-4220(64)90320-2","article-title":"Double dens in dente in a single tooth. Report of a case and radiologic study of the incidence of small dens in dente","volume":"17","author":"Ulmansky","year":"1964","journal-title":"Oral Med Oral Surg Oral Pathol"},{"key":"B36","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1055\/s-0039-1697408","article-title":"Double dens invaginatus: report of three cases","volume":"3","author":"Zengin","year":"2009","journal-title":"Eur J Dent"},{"key":"B37","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1007\/s11282-017-0295-7","article-title":"Cone-beam computed tomography for assessment of dens invaginatus in the Polish population","volume":"34","author":"R\u00f3zylo","year":"2018","journal-title":"Oral Radiol"},{"key":"B38","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1016\/j.joen.2014.12.001","article-title":"A retrospective comparative study of cone-beam computed tomography versus rendered panoramic images in identifying the presence, types, and characteristics of dens invaginatus in a Turkish population","volume":"41","author":"Capar","year":"2015","journal-title":"J Endod"},{"key":"B39","first-page":"115","article-title":"Dens invaginatus. I. A clinical, roentgenological and genetical study of permanent upper lateral incisors","volume":"10","author":"Grahn\u00e9n","year":"1959","journal-title":"Odontologisk Revy"},{"key":"B40","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1111\/j.0143-2885.2004.00797.x","article-title":"Prevalence of dens invaginatus in Jordanian adults","volume":"37","author":"Hamasha","year":"2004","journal-title":"Int Endod J"},{"key":"B41","doi-asserted-by":"publisher","first-page":"e27","DOI":"10.4317\/medoral.18285","article-title":"A retrospective study of the prevalence and characteristics of dens invaginatus in a sample of the Turkish population","volume":"18","author":"G\u00fcnd\u00fcz","year":"2013","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"B42","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1111\/j.1600-051X.1990.tb01089.x","article-title":"Studies on root enamel (2). Enamel pearls. A review of their morphology, localization, nomenclature, occurrence, classification, histogenesis and incidence","volume":"17","author":"Moskow","year":"1990","journal-title":"J Clin Periodontol"},{"key":"B43","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1111\/j.1600-0722.1974.tb00395.x","article-title":"The prevalence and distribution of cervical enamel projections reaching into the bifurcation on human molars","volume":"82","author":"Risnes","year":"1974","journal-title":"Scand J Dent Res."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1016\/j.archoralbio.2015.03.010","article-title":"Microscopic study of dental hard tissues in primary teeth with dentinogenesis imperfecta type II: correlation of 3D imaging using X-ray microtomography and polarising microscopy","volume":"60","author":"Davis","year":"2015","journal-title":"Arch Oral Biol"},{"key":"B45","doi-asserted-by":"publisher","first-page":"e311","DOI":"10.1016\/j.oooo.2013.06.030","article-title":"Root malformation associated with a cervical mineralized diaphragm \u2013 a distinct form of tooth abnormality?","volume":"117","author":"Witt","year":"","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol. ("},{"key":"B46","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1016\/j.oooo.2014.10.013","article-title":"Microscopic analysis of molar-incisor malformation","volume":"119","author":"Lee","year":"2015","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"B47","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.oooo.2017.03.050","article-title":"Molar incisor malformation in six cases: description and diagnostic protocol","volume":"124","author":"Brusevold","year":"2017","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"B48","doi-asserted-by":"publisher","first-page":"370","DOI":"10.5933\/JKAPD.2017.44.3.370","article-title":"Molar-incisor malformation: three cases of a newly identified dental anomaly","volume":"44","author":"Choi","year":"2017","journal-title":"J Korean Acad Pediatr Dent"},{"key":"B49","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/j.joen.2015.11.004","article-title":"Nonsurgical endodontic management of a molar-incisor malformation-affected mandibular first molar: a case report","volume":"42","author":"Yue","year":"2016","journal-title":"J Endod"},{"key":"B50","doi-asserted-by":"publisher","first-page":"e164","DOI":"10.1016\/j.oooo.2016.11.024","article-title":"Symmetric multiquadrant isolated dentin dysplasia (SMIDD), a unique presentation mimicking dentin dysplasia type 1b","volume":"123","author":"Qari","year":"2017","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"B51","first-page":"33","article-title":"Molar-incisor malformation: two cases of a newly described dental anomaly","volume":"83","author":"McCreedy","year":"2016","journal-title":"J Dent Child"},{"key":"B52","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.oooo.2014.03.014","article-title":"A new type of dental anomaly: molar-incisor malformation (MIM)","volume":"118","author":"Lee","year":"2014","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"B53","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.oooo.2015.08.024","article-title":"Molar root-incisor malformation: considerations of diverse developmental and etiologic factors","volume":"121","author":"Wright","year":"2016","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"B54","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.archoralbio.2017.04.009","article-title":"Variable expressivity of TCTEX1D2 mutations and a possible pathogenic link of molar-incisor malformation to ciliary dysfunction","volume":"80","author":"Zschocke","year":"2017","journal-title":"Arch Oral Biol"},{"key":"B55","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1111\/j.1365-2591.2008.01374.x","article-title":"Pulp stones: a review","volume":"41","author":"Goga","year":"2008","journal-title":"Int Endod J"},{"key":"B56","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1177\/089875649200900301","article-title":"Dens in dente in a six year old doberman pinscher","volume":"9","author":"DeForge","year":"1992","journal-title":"J Vet Dent"},{"key":"B57","first-page":"1118","article-title":"Zur Frage der Hartsubstanzneubildung in der Pulpa, zugleich ein Beitrag zur Frage \u201cDens in dente\u201d","volume":"31","author":"Hattyasy","year":"1933","journal-title":"Ztschr f Stom"},{"key":"B58","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1177\/089875640902600409","article-title":"Endodontic treatment of dens invaginatus in a dog","volume":"26","author":"Coffman","year":"2009","journal-title":"J Vet Dent"},{"key":"B59","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1111\/j.1439-0531.2009.01405.x","article-title":"Dystocia in numbers - evidence-based parameters for intervention in the dog: causes for dystocia and treatment recommendations","volume":"44","author":"M\u00fcnnich","year":"2009","journal-title":"Reprod Domest Anim."},{"key":"B60","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1136\/vr.104108","article-title":"Canine dystocia in 50 UK first-opinion emergency care veterinary practices: prevalence and risk factors","volume":"181","author":"O'Neill","year":"2017","journal-title":"Vet Rec."},{"key":"B61","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1177\/089875640101800202","article-title":"Mandible and mandibular first molar tooth measurements in dogs: Relationship of radiographic height to body weight","volume":"18","author":"Gioso","year":"2001","journal-title":"J Vet Dent"},{"key":"B62","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1177\/0898756418777861","article-title":"A volumetric assessment using computed tomography of canine and first molar roots in dogs of varying weight","volume":"35","author":"Scherer","year":"2018","journal-title":"J Vet Dent"}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fvets.2019.00464\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T16:36:07Z","timestamp":1613147767000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fvets.2019.00464\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,17]]},"references-count":62,"alternative-id":["10.3389\/fvets.2019.00464"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2019.00464","relation":{},"ISSN":["2297-1769"],"issn-type":[{"type":"electronic","value":"2297-1769"}],"subject":[],"published":{"date-parts":[[2019,12,17]]},"article-number":"464"}}