{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:13:29Z","timestamp":1793052809327,"version":"4.5.0"},"reference-count":56,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T00:00:00Z","timestamp":1595462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"DOI":"10.3389\/fvets.2020.00376","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T08:43:42Z","timestamp":1595580222000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":35,"title":["Molecular Detection and Characterization of the mecA and nuc Genes From Staphylococcus Species (S. aureus, S. pseudintermedius, and S. schleiferi) Isolated From Dogs Suffering Superficial Pyoderma and Their Antimicrobial Resistance Profiles"],"prefix":"10.3389","volume":"7","author":[{"given":"Mar\u00eda S.","family":"Gonz\u00e1lez-Dom\u00ednguez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hern\u00e1n D.","family":"Carvajal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Calle-Echeverri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny","family":"Chinchilla-C\u00e1rdenas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,7,23]]},"reference":[{"key":"B1","volume-title":"Muller & Kirk's Small Animal Dermatology","author":"Miller","year":"2013"},{"key":"B2","doi-asserted-by":"publisher","first-page":"e01194","DOI":"10.1128\/genomeA.01194-16","article-title":"Complete genome sequences of three important methicillin-resistant clinical isolates of Staphylococcus pseudintermedius","volume":"4","author":"Riley","year":"2016","journal-title":"Genome Announc."},{"key":"B3","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1177\/104063871102300227","article-title":"Prevalence, sites of colonization, and antimicrobial resistance among Staphylococcus pseudintermedius isolated from healthy dogs in Saskatoon, Canada","volume":"23","author":"Rubin","year":"2011","journal-title":"J Vet Diagn Invest."},{"key":"B4","doi-asserted-by":"publisher","first-page":"e51","DOI":"10.1111\/j.1365-3164.2012.01046.x","article-title":"Staphylococcus pseudintermedius in the dog: taxonomy, diagnostics, ecology, epidemiology and pathogenicity","volume":"23","author":"Bannoehr","year":"2012","journal-title":"Vet Dermatol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.vetmic.2008.06.002","article-title":"Staphylococcus pseudintermedius versus Staphylococcus intermedius","volume":"133","author":"Devriese","year":"2009","journal-title":"Vet Microbiol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1111\/avj.12176","article-title":"Canine superficial bacterial pyoderma: evaluation of skin surface sampling methods and antimicrobial susceptibility of causal Staphylococcus isolates","volume":"92","author":"Ravens","year":"2014","journal-title":"Aust Vet J."},{"key":"B7","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1111\/j.1365-3164.2006.00550.x","article-title":"Pyoderma caused by Pseudomonas aeruginosa infection in dogs: 20 cases","volume":"17","author":"Hillier","year":"2006","journal-title":"Vet Dermatol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1084\/jem.125.1.45","article-title":"In vivo transmission of drug resistance factors between strains of Staphylococcus aureus","volume":"125","author":"Novick","year":"1967","journal-title":"J Exp Med."},{"key":"B9","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.vetmic.2003.09.021","article-title":"Transmission of multiple antimicrobial-resistant Staphylococcus intermedius between dogs affected by deep pyoderma and their owners","volume":"98","author":"Guardabassi","year":"2004","journal-title":"Vet Microbiol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/j.jhin.2009.09.020","article-title":"Meticillin-resistant Staphylococcus aureus carriage in UK veterinary staff and owners of infected pets: new risk groups","volume":"74","author":"Loeffler","year":"2010","journal-title":"J Hosp Infect."},{"key":"B11","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1186\/s12917-019-1990-x","article-title":"Identification and molecular epidemiology of methicillin resistant Staphylococcus pseudintermedius strains isolated from canine clinical samples in Argentina","volume":"15","author":"Gagetti","year":"2019","journal-title":"BMC Vet Res."},{"key":"B12","doi-asserted-by":"publisher","first-page":"702","DOI":"10.3390\/microorganisms7120702","article-title":"Investigation on antibiotic-resistance, biofilm formation and virulence factors in multi drug resistant and non multi drug resistant Staphylococcus pseudintermedius","volume":"7","author":"Meroni","year":"2019","journal-title":"Microorganisms."},{"key":"B13","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.vetmic.2012.06.015","article-title":"Prevalence and characterization of methicillin-resistant Staphylococcus pseudintermedius in pets from South China","volume":"160","author":"Feng","year":"2012","journal-title":"Vet Microbiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1111\/j.1863-2378.2011.01398.x","article-title":"Carriage of methicillin-resistant Staphylococcus pseudintermedius in small animal veterinarians: indirect evidence of zoonotic transmission: methicilln-resistant Staphylococcus pseudintermedius in veterinarians","volume":"58","author":"Paul","year":"2011","journal-title":"Zoonoses Public Health."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1038\/s41598-018-37503-9","article-title":"Combining MALDI-TOF and genomics in the study of methicillin resistant and multidrug resistant Staphylococcus pseudintermedius in New Zealand","volume":"9","author":"Nisa","year":"2019","journal-title":"Sci Rep."},{"key":"B16","doi-asserted-by":"publisher","first-page":"e00684","DOI":"10.1128\/mSystems.00684-19","article-title":"Prophage-mediated disruption of genetic competence in Staphylococcus pseudintermedius","volume":"5","author":"Brooks","year":"2020","journal-title":"mSystems."},{"key":"B17","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.vetmic.2017.11.022","article-title":"Methicillin-resistant Staphylococcus pseudintermedius among dogs in the description of novel SCCmec variants","volume":"213","author":"Duim","year":"2018","journal-title":"Vet Microbiol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.vetmic.2019.04.002","article-title":"Molecular characterisation of methicillin-resistant Staphylococcus pseudintermedius from dogs and the description of their SCCmec elements","volume":"233","author":"Krapf","year":"2019","journal-title":"Vet Microbiol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.micpath.2016.10.028","article-title":"Staphylococcal chromosomal cassettes mec (SCCmec): a mobile genetic element in methicillin-resistant Staphylococcus aureus","volume":"101","author":"Liu","year":"2016","journal-title":"Microb Pathog."},{"key":"B20","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1128\/AAC.45.5.1323-1336.2001","article-title":"Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus","volume":"45","author":"Ito","year":"2001","journal-title":"Antimicrob Agents Chemother."},{"key":"B21","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1128\/CVI.00482-07","article-title":"Genetic and antigenic diversities of major immunoreactive proteins in globally distributed Ehrlichia canis strains","volume":"15","author":"Zhang","year":"2008","journal-title":"Clin Vaccine Immunol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"2302","DOI":"10.4315\/0362-028X-67.10.2302","article-title":"Development of a PCR test to differentiate between Staphylococcus aureus and Staphylococcus intermedius","volume":"67","author":"Baron","year":"2004","journal-title":"J Food Prot."},{"key":"B23","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.1016\/j.rvsc.2011.01.027","article-title":"Genetic relatedness of methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolated from a dog and the dog owner","volume":"91","author":"Soedarmanto","year":"2011","journal-title":"Res Vet Sci."},{"key":"B24","doi-asserted-by":"crossref","unstructured":"API Staph. Rf 20 500. 07468K - es - 2009\/11. IVD2009","DOI":"10.1055\/s-0029-1237829"},{"key":"B25","article-title":"Clinical and Laboratory Standards Institute","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement","author":"Cockerill","year":"2012"},{"key":"B26","doi-asserted-by":"publisher","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: a new generation of protein database search programs","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"B27","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1590\/S0101-20612011000400019","article-title":"Standardization of a multiplex PCR for the identification of coagulase-positive Staphylococcus","volume":"31","author":"Gandra","year":"2011","journal-title":"Ci\u00eancia Tecnologia Alimentos"},{"key":"B28","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1128\/JCM.01232-09","article-title":"Multiplex-PCR method for species identification of coagulase-positive staphylococci","volume":"48","author":"Sasaki","year":"2010","journal-title":"J Clin Microbiol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.mcp.2016.07.007","article-title":"Corrigendum to \u201cDevelopment of a DNA-based microarray for the detection of zoonotic pathogens in rodent species\u201d","volume":"30","author":"Giles","year":"2016","journal-title":"Mol Cell Probes"},{"key":"B30","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.mcp.2015.07.005","article-title":"Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species","volume":"29","author":"Giles","year":"2015","journal-title":"Mol Cell Probes."},{"key":"B31","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/1746-6148-10-17","article-title":"Antimicrobial resistance and characterisation of staphylococci isolated from healthy labrador retrievers in the United Kingdom","volume":"10","author":"Schmidt","year":"2014","journal-title":"BMC Vet Res."},{"key":"B32","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.tvjl.2018.04.002","article-title":"What has changed in canine pyoderma? A narrative review","volume":"235","author":"Loeffler","year":"2018","journal-title":"Vet J."},{"key":"B33","first-page":"99","article-title":"Survey of dermatological conditions in a population of domestic dogs in Mashhad, northeast of Iran (2007-2011)","volume":"4","author":"Khoshnegah","year":"2013","journal-title":"Vet Res Forum."},{"key":"B34","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1093\/jac\/dkx086","article-title":"Antimicrobial resistance in Staphylococcus pseudintermedius and the molecular epidemiology of methicillin-resistant S. pseudintermedius in small animals in Finland","volume":"72","author":"Gr\u00f6nthal","year":"2017","journal-title":"J Antimicrob Chemother."},{"key":"B35","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.vetmic.2017.08.017","article-title":"Clonal distribution of methicillin-resistant Staphylococcus pseudintermedius isolates from skin infection of dogs in Korea","volume":"210","author":"Kang","year":"2017","journal-title":"Vet Microbiol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"3641","DOI":"10.1128\/JCM.01253-14","article-title":"Amikacin resistance in Staphylococcus pseudintermedius isolated from dogs","volume":"52","author":"Gold","year":"2014","journal-title":"J Clin Microbiol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"e43","DOI":"10.1111\/vde.12209","article-title":"Lincosamide resistance is less frequent in Denmark in Staphylococcus pseudintermedius from first-time canine superficial pyoderma compared with skin isolates from clinical samples with unknown clinical background","volume":"26","author":"Larsen","year":"2015","journal-title":"Vet Dermatol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1186\/1746-6148-8-225","article-title":"Efficacy of clarithromycin on biofilm formation of methicillin-resistant Staphylococcus pseudintermedius","volume":"8","author":"Dicicco","year":"2012","journal-title":"BMC Vet Res."},{"key":"B39","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1177\/1040638717742434","article-title":"Cephalexin susceptibility breakpoint for veterinary isolates: clinical laboratory standards institute revision","volume":"30","author":"Papich","year":"2018","journal-title":"J Vet Diagn Invest."},{"key":"B40","first-page":"678","article-title":"Resistance to fluoroquinolones and methicillin in ophthalmic isolates of Staphylococcus pseudintermedius from companion animals","volume":"55","author":"Kang","year":"2014","journal-title":"Can Vet J."},{"key":"B41","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.vetmic.2012.08.001","article-title":"Susceptibility of canine and feline bacterial pathogens to pradofloxacin and comparison with other fluoroquinolones approved for companion animals","volume":"162","author":"Schink","year":"2013","journal-title":"Vet Microbiol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/lam.12254","article-title":"Carriage of methicillin-resistant staphylococci by healthy companion animals in the US","volume":"59","author":"Davis","year":"2014","journal-title":"Lett Appl Microbiol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.vetmic.2013.10.023","article-title":"Case\u2013control risk factor study of methicillin-resistant Staphylococcus pseudintermedius (MRSP) infection in dogs and cats in Germany","volume":"168","author":"Lehner","year":"2014","journal-title":"Vet Microbiol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"e0130385","DOI":"10.1371\/journal.pone.0130385","article-title":"Antibacterial characterization of novel synthetic thiazole compounds against methicillin-resistant Staphylococcus pseudintermedius","volume":"10","author":"Mohammad","year":"2015","journal-title":"PLoS ONE."},{"key":"B45","doi-asserted-by":"publisher","first-page":"e116259","DOI":"10.1371\/journal.pone.0116259","article-title":"Antibacterial activity of novel cationic peptides against clinical isolates of multi-drug resistant Staphylococcus pseudintermedius from infected dogs","volume":"9","author":"Mohamed","year":"2014","journal-title":"PLoS ONE."},{"key":"B46","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1111\/vde.12091","article-title":"Canine antimicrobial peptides are effective against resistant bacteria and yeasts","volume":"25","author":"Santoro","year":"2014","journal-title":"Vet Dermatol."},{"key":"B47","first-page":"999","article-title":"Efficacy of orbifloxacin tablets for the treatment of superficial and deep pyoderma due to Staphylococcus intermedius infection in dogs","volume":"47","author":"Scott","year":"2006","journal-title":"Can Vet J."},{"key":"B48","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1046\/j.1365-3164.2001.00195.x","article-title":"Evaluation of the clinical efficacy of marbofloxacin (Zeniquin) tablets for the treatment of canine pyoderma: an open clinical trial","volume":"12","author":"Paradis","year":"2001","journal-title":"Vet Dermatol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"301","DOI":"10.5326\/0460301","article-title":"Evaluation of the clinical efficacy of pradofloxacin tablets for the treatment of canine pyoderma","volume":"46","author":"Restrepo","year":"2010","journal-title":"J Am Anim Hosp Assoc."},{"key":"B50","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.rvsc.2014.02.004","article-title":"Fosfomycin susceptibility of canine methicillin-resistant Staphylococcus pseudintermedius isolates","volume":"96","author":"DiCicco","year":"2014","journal-title":"Res Vet Sci."},{"key":"B51","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.cvsm.2012.09.003","article-title":"Antimicrobial resistance in staphylococci in small animals","volume":"43","author":"Cain","year":"2013","journal-title":"Vet Clin North Am Small Anim Pract."},{"key":"B52","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1111\/vde.12549","article-title":"Diversity of Staphylococcus pseudintermedius in carriage sites and skin lesions of dogs with superficial bacterial folliculitis: potential implications for diagnostic testing and therapy","volume":"29","author":"Larsen","year":"2018","journal-title":"Vet Dermatol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/S0716-8640(14)70072-0","article-title":"Laboratorio de microbiolog\u00eda: conocimientos b\u00e1sicos para un cl\u00ednico","volume":"25","author":"M\u00fchlhauser","year":"2014","journal-title":"Revista M\u00e9dica Cl\u00ednica Las Condes."},{"key":"B54","volume-title":"Koneman Diagn\u00f3stico Microbiol\u00f3gico: Texto y Atlas en Color","author":"Koneman","year":"2018"},{"key":"B55","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.3389\/fmicb.2016.01599","article-title":"Systematic review on global epidemiology of methicillin-resistant Staphylococcus pseudintermedius: inference of population structure from multilocus sequence typing data","volume":"7","author":"Pires dos Santos","year":"2016","journal-title":"Front Microbiol."},{"key":"B56","doi-asserted-by":"publisher","first-page":"jmmcr005087","DOI":"10.1099\/jmmcr.0.005087","article-title":"Skin infection caused by a novel strain of Staphylococcus pseudintermedius in a Siberian husky dog owner","volume":"4","author":"Robb","year":"2017","journal-title":"JMM Case Rep."}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fvets.2020.00376\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T08:43:46Z","timestamp":1595580226000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fvets.2020.00376\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,23]]},"references-count":56,"alternative-id":["10.3389\/fvets.2020.00376"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2020.00376","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,23]]},"article-number":"376"}}