{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T10:49:10Z","timestamp":1792752550714,"version":"4.5.0"},"reference-count":43,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015815","name":"Consortium of International Agricultural Research Centers","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015815","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009053","name":"Bill and Melinda Gates Institute for Population and Reproductive Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p><jats:italic>Taenia solium<\/jats:italic> cysticercosis disease remains a key challenge to the pig sector in low- and middle-income countries in sub-Saharan Africa, Latin America and South East Asia, resulting in both economic losses and public health impacts. The World Health Organization has ranked it first on the global scale of foodborne parasites. A One Health approach has been recommended for reduction of infection pressure and eradication in the longer term. A new vaccine TSOL18 (Cysvax\u2122), applied in combination with oxfendazole (Paranthic 10%\u2122), a dewormer drug has been developed and field tested for the control of <jats:italic>T. solium<\/jats:italic> cysticercosis, with high potential to break the disease cycle. It is however unclear whether the products can be marketed through a market driven approach, and if smallholder pig farmers would be willing to take up and pay for the vaccine\u2013oxfendazole combination. A choice experiment methodology was used to assess the potential demand and willingness to pay for the vaccine\u2014oxfendazole combination by Ugandan smallholder pig farmers, and demand for vaccinated pigs by pig traders. The results showed that farmers highly valued quality assurance attributes and were not keen on the vaccine if there were no associated returns in the form of premium price for vaccinated pigs during sales. They were willing to pay US$ 2.31 for the vaccine if it resulted in a premium price for vaccinated pigs. Furthermore, they preferred an accompanying vaccine viability detector as part of its quality assurance. The pig traders on the other hand preferred high carcass weight of pigs, potentially achieved by using oxfendazole. The results show that unless the pig market systems pay a premium price for vaccinated pigs, and quality assurance systems guarantee quality vaccine, uptake of the TSOL18 vaccine and oxfendazole by farmers through market mechanisms may be unsuccessful. The current pig marketing system does not reward food safety, the focus is mainly on carcass weight. Alternative delivery mechanisms for the vaccine through a mix of private\u2013public investments needs to be explored, as the benefits of vaccinated pigs are societal and include reduction and elimination of neurocysticercosis in the long run.<\/jats:p>","DOI":"10.3389\/fvets.2021.611166","type":"journal-article","created":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T04:32:26Z","timestamp":1619497946000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":14,"title":["Demand for Taenia solium Cysticercosis Vaccine: Lessons and Insights From the Pig Production and Trading Nodes of the Uganda Pig Value Chain"],"prefix":"10.3389","volume":"8","author":[{"given":"Emily","family":"Ouma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Dione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadhem","family":"Mtimet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Lule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angie","family":"Colston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Adediran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delia","family":"Grace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,4,27]]},"reference":[{"key":"B1","first-page":"17","volume-title":"Assembling a Framework for Intensified Control of Taeniasis and Neurocysticercosis Caused by Taenia solium: Report of an Informal Consultation","year":"2015"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pntd.0002096","article-title":"Neurocysticercosis: HP10 antigen detection is useful for the follow-up of the severe patients","volume":"7","author":"Fleury","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1570","DOI":"10.1016\/S0140-6736(09)60233-6","article-title":"Rescuing the bottom billion through control of neglected tropical diseases","volume":"373","author":"Hotez","year":"2009","journal-title":"Lancet"},{"key":"B4","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.actatropica.2016.04.010","article-title":"Control of Taenia solium taeniasis\/cysticercosis: the best way forward for sub-Saharan Africa?","volume":"165","author":"Gabri\u00ebl","year":"2017","journal-title":"Acta Trop"},{"key":"B5","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S0001-706X(03)00050-0","article-title":"Background to the international action planning workshop on Taenia solium cysticercosis\/taeniosis with special focus on Eastern and Southern Africa","volume":"87","author":"Mukaratirwa","year":"2003","journal-title":"Acta Trop"},{"key":"B6","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.pt.2005.05.009","article-title":"Methods for assessing the burden of parasitic zoonoses: echinococcosis and cysticercosis","volume":"21","author":"Carabin","year":"2005","journal-title":"Trends Parasitol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pntd.0000284","article-title":"Spatial distribution of Taenia solium porcine cysticercosis within a rural area of Mexico","volume":"2","author":"Morales","year":"2008","journal-title":"PLoS Negl Trop Dis"},{"key":"B8","doi-asserted-by":"publisher","first-page":"e2102","DOI":"10.1371\/journal.pntd.0002102","article-title":"Prevalence and risk factors associated with human Taenia solium infections in Mbozi District, Mbeya Region, Tanzania","volume":"7","author":"Mwanjali","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"B9","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.vetpar.2012.12.022","article-title":"Taenia solium taeniosis\/cysticercosis in Africa: Risk factors, epidemiology and prospects for control using vaccination","volume":"195","author":"Assana","year":"2013","journal-title":"Vet Parasitol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"e00082","DOI":"10.1016\/j.parepi.2018.e00082","article-title":"Taenia solium control in Zambia: the potholed road to success","volume":"4","author":"Gabri\u00ebl","year":"2019","journal-title":"Parasite Epidemiol Control"},{"key":"B11","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.actatropica.2015.12.019","article-title":"Seroprevalence and risk factors of human cysticercosis and taeniasis prevalence in a highly endemic area of epilepsy in Bangoua, west Cameroon","volume":"165","author":"Nkouawa","year":"2017","journal-title":"Acta Trop"},{"key":"B12","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.vetpar.2013.09.020","article-title":"Prevalence of porcine cysticercosis and associated risk factors in smallholder pig production systems in Mbeya region, southern highlands of Tanzania","volume":"198","author":"Komba","year":"2013","journal-title":"Vet Parasitol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1016\/S0140-6736(17)32130-X","article-title":"Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"390","author":"Hay","year":"2017","journal-title":"Lancet"},{"key":"B14","doi-asserted-by":"publisher","first-page":"e817","DOI":"10.1371\/journal.pntd.0000817","article-title":"Taenia solium cysticercosis in the democratic Republic of Congo: How does pork trade affect the transmission of the parasite?","volume":"4","author":"Praet","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1016\/S0140-6736(17)32367-X","article-title":"Measuring global health: motivation and evolution of the Global Burden of Disease Study","volume":"390","author":"Murray","year":"2017","journal-title":"Lancet"},{"key":"B16","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0001-706X(03)00053-6","article-title":"Regional status, epidemiology and impact of Taenia solium cysticercosis in Western and Central Africa","volume":"87","author":"Zoli","year":"2003","journal-title":"Acta Trop"},{"key":"B17","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/S0065-308X(05)61012-3","article-title":"Control of Taenia solium cysticercosis\/taeniosis","volume":"61","author":"Willingham","year":"2006","journal-title":"Adv Parasitol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1016\/j.ijpara.2010.05.001","article-title":"Eradication of Taenia solium cysticercosis: a role for vaccination of pigs","volume":"40","author":"Lightowlers","year":"2010","journal-title":"Int J Parasitol"},{"key":"B19","volume-title":"Veterinary Vaccinology in the One Health Perspective Introduction","author":"Colston","year":"2018"},{"key":"B20","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.ijpara.2010.01.006","article-title":"Elimination of Taenia solium transmission to pigs in a field trial of the TSOL18 vaccine in Cameroon","volume":"40","author":"Assana","year":"2010","journal-title":"Int J Parasitol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pntd.0006838","article-title":"Implementation of a practical and effective pilot intervention against transmission of Taenia solium by pigs in the banke district of Nepal","volume":"13","author":"Poudel","year":"2019","journal-title":"PLoS Negl Trop Dis"},{"key":"B22","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1080\/00128325.2015.1040646","article-title":"Adoption of east coast fever vaccine among smallholder dairy farmers in Kenya: the case of North Rift Kenya","volume":"81","author":"Karanja-Lumumba","year":"2015","journal-title":"East African Agric For J"},{"key":"B23","article-title":"Developing sustainable value chains for small-scale producers. In: Leroy G, Fernando M, editors","volume-title":"FAO Animal Production and Health Guidelines No. 21","year":"2019"},{"key":"B24","volume-title":"Statistical Abstract","year":"2018"},{"key":"B25","unstructured":"SHORT COMMUNICATION Cysticcrcus ccllulosae in pigs slaughtered234\n            KisakyeJJM\n            MasaboSC\n          Uganda J Agric Sci72002"},{"key":"B26","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1186\/s12917-014-0239-y","article-title":"Prevalence of porcine cysticercosis in the Lake Kyoga Basin, Uganda","volume":"10","author":"Nsadha","year":"2014","journal-title":"BMC Vet Res"},{"key":"B27","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1086\/259131","article-title":"A new approach to consumer theory","volume":"74","author":"Lancaster","year":"1966","journal-title":"J Polit Econ"},{"key":"B28","volume-title":"Discrete Choice Methids With Simulation","author":"Train","year":"2009"},{"key":"B29","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1111\/j.1477-9552.2011.00330.x","article-title":"Farmers willingness to pay for Tuberculosis cattle vaccine","volume":"63","author":"Bennett","year":"2012","journal-title":"J Agric Econ"},{"key":"B30","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.prevetmed.2018.08.004","article-title":"Eliciting preferences for attributes of Newcastle disease vaccination programmes for village poultry in Ethiopia","volume":"158","author":"Terfa","year":"2018","journal-title":"Prev Vet Med"},{"key":"B31","doi-asserted-by":"publisher","first-page":"100144","DOI":"10.1016\/j.wdp.2019.100144","article-title":"Enhancing livestock vaccination decision-making through rapid diagnostic testing","volume":"16","author":"Railey","year":"2019","journal-title":"World Dev Perspect"},{"key":"B32","first-page":"1","volume-title":"Marketing Research Methods in SAS","author":"Kuhfeld","year":"2010"},{"key":"B33","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1080\/01441640902827623","article-title":"Constructing efficient stated choice experimental designs","volume":"29","author":"Rose","year":"2009","journal-title":"Transp Rev"},{"key":"B34","doi-asserted-by":"publisher","first-page":"488","DOI":"10.2307\/1879431","article-title":"The market for \u201clemons\u201d: quality uncertainty and the market mechanism","volume":"84","author":"Akerlof","year":"1970","journal-title":"Q J Econ"},{"key":"B35","article-title":"Smallholder Pig Value Chain Assessment in Uganda : Results From Producer Focus Group Discussions and Key Informant Interviews","volume-title":"ILRI(Research Report)","author":"Ouma","year":"2014"},{"key":"B36","unstructured":"Do beliefs about agricultural inputs counterfeiting correspond with actual rates of counterfeiting?40\n            AshourM\n            BillingsL\n            GilliganD\n            HoelJB\n            KarachiwallaN\n          Evidence from Uganda2016"},{"key":"B37","doi-asserted-by":"publisher","first-page":"488","DOI":"10.3389\/fvets.2019.00488","article-title":"Willingness to Vaccinate (WTV) and Willingness to Pay (WTP) for Vaccination Against Peste des Petits Ruminants (PPR) in Mali","volume":"6","author":"Wane","year":"2020","journal-title":"Front Vet Sci"},{"key":"B38","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.vaccine.2018.11.058","article-title":"Drivers of vaccination preferences to protect a low-value livestock resource: willingness to pay for Newcastle disease vaccines by smallholder households","volume":"37","author":"Campbell","year":"2019","journal-title":"Vaccine"},{"key":"B39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1756-0500-7-894","article-title":"Measuring the quality of clinical veterinary services for Cattle: an application of a role play experiment in rural Uganda","volume":"7","author":"Ilukor","year":"2014","journal-title":"BMC Res Notes"},{"key":"B40","article-title":"Possibilities for Smallholder Poultry Projects in Eastern and Southern Africa","volume-title":"\u2014 Proceedings of a Workshop","author":"Pedersen","year":""},{"key":"B41","unstructured":"Elimination of Taenia solium cysticercosis through vaccination of pigs: a realistic option?116\n            GeertsS\n          2016"},{"key":"B42","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1080\/09614524.2017.1363873","article-title":"Analysing pig traders in Uganda: sampling issues, marketing activities, and constraint analysis","volume":"28","author":"Mtimet","year":"2018","journal-title":"Dev Pract"},{"key":"B43","doi-asserted-by":"publisher","first-page":"176","DOI":"10.3389\/fvets.2019.00176","article-title":"Control of Taenia solium; a case for public and private sector investment","volume":"6","author":"Thomas","year":"2019","journal-title":"Front Vet Sci"}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2021.611166\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T04:32:44Z","timestamp":1619497964000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2021.611166\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,27]]},"references-count":43,"alternative-id":["10.3389\/fvets.2021.611166"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2021.611166","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,27]]},"article-number":"611166"}}