{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:35:30Z","timestamp":1753893330212,"version":"3.41.2"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T00:00:00Z","timestamp":1619654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>An 8-year-old male neutered Domestic Long Hair cat was presented for a cervical swelling that was suspected to be an enlarged left retropharyngeal lymph node. In the absence of other lymphadenopathy, this was initially suspected to be Hodgkin's-like lymphoma. A positron emission tomography\u2013computed tomography (PET\/CT) scan was performed using 2-deoxy-2-[<jats:sup>18<\/jats:sup>F]-fluorodeoxyglucose (<jats:sup>18<\/jats:sup>F-FDG) to assess for evidence of disease in other locations to guide treatment. Multifocal increased radiopharmaceutical uptake was identified, indicating disease in multiple organs. High-grade lymphoma was confirmed on tissue biopsy. As such, systemic cytotoxic chemotherapy was recommended instead of lymph node extirpation surgery. The cat received a modified CHOP chemotherapy protocol and attained a temporary partial remission. After 2 months of treatment, the cat stopped responding to chemotherapy and was eventually euthanized due to a relapse of disease and decreased quality of life. This case describes the utility of PET\/CT to guide treatment in a cat with a presentation consistent with Hodgkin's-like lymphoma.<\/jats:p>","DOI":"10.3389\/fvets.2021.619264","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T05:34:40Z","timestamp":1619674480000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: Use of PET\/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma"],"prefix":"10.3389","volume":"8","author":[{"given":"Carolyn L.","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew R.","family":"Cook","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan E.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Lumbrezer-Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric T.","family":"Hostnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janis M.","family":"Lapsley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip","family":"Lerche","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent A.","family":"Wavreille","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria I.","family":"Menendez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael V.","family":"Knopp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah C.","family":"Linn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Premanandan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura E.","family":"Selmic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,4,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1111\/j.1939-1676.2007.0031.x","article-title":"Efficacy and toxicosis of VELCAP-C treatment of lymphoma in cats","volume":"22","author":"Hadden","year":"2008","journal-title":"J Vet Intern Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1111\/j.1939-1676.2001.tb01243.x","article-title":"Single agent chemotherapy with doxorubicin for feline lymphoma: a retrospective study of 19 cases (1994-1997)","volume":"15","author":"Kristal","year":"2001","journal-title":"J Vet Intern Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1111\/j.1939-1676.1996.tb02083.x","article-title":"A comparison of doxorubicin and COP for maintenance of remission in cats with lymphoma","volume":"10","author":"Moore","year":"1996","journal-title":"J Vet Intern Med."},{"key":"B4","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1111\/j.1939-1676.2008.0057.x","article-title":"Combination chemotherapy in feline lymphoma: treatment outcome, tolerability, and duration in 23 cats","volume":"22","author":"Simon","year":"2008","journal-title":"J Vet Intern Med."},{"key":"B5","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1111\/j.1939-1676.2002.tb02352.x","article-title":"Chemotherapy with cyclophosphamide, vincristine, and prednisolone (COP) in cats with malignant lymphoma: new results with an old protocol","volume":"16","author":"Teske","year":"2002","journal-title":"J Vet Intern Med."},{"key":"B6","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/978-3-319-12505-3_7","article-title":"Functional imaging in Hodgkin lymphoma.","volume-title":"Hodgkin Lymphoma","author":"Gallamini","year":"2015"},{"key":"B7","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/B978-0-7020-2800-7.00026-1","volume-title":"Tumours of the Haemolymphatic System. 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