{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T15:00:03Z","timestamp":1793458803290,"version":"4.5.0"},"reference-count":82,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,5,7]],"date-time":"2021-05-07T00:00:00Z","timestamp":1620345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFD0500900"],"award-info":[{"award-number":["2018YFD0500900"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010211","name":"Education Department of Jilin Province","doi-asserted-by":"publisher","award":["JJKH20200364KJ"],"award-info":[{"award-number":["JJKH20200364KJ"]}],"id":[{"id":"10.13039\/501100010211","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p><jats:bold>Background:<\/jats:bold>Brucellosis, a zoonotic disease, infects various hosts, including swine and humans. It has reemerged in recent years as a public health concern, and current studies on brucellosis infection in swine have been conducted worldwide. However, no meta-analyses of global brucellosis infection in swine have been published. The aim of this study was to provide an overview of<jats:italic>Brucella<\/jats:italic>species (spp.) in swine worldwide and the factors associated with its persistence.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold>We searched seven databases for published epidemiological studies on brucellosis in pigs, including the Chinese National Knowledge Infrastructure, Wanfang Data, SpringerLink, ScienceDirect, Web of Science, the VIP Chinese Journal Database and PubMed. We selected 119 articles published from January 1, 2000 to January 3, 2020 for inclusion in the meta-analysis and analyzed the data using a random-effects model. Funnel plots and Egger's test showed significant publication bias in the included studies. The results of the sensitivity analysis showed that our study was relatively stable and reliable. The prevalence of brucellosis in swine was 2.1% (95% CI: 1.6\u20132.6), of which the highest infection rate, which was found in Europe, was 17.4% (95% CI: 11.1\u201324.9). The prevalence in feral pigs (15.0%, 95% CI: 8.4\u201323.2) was higher than that in domestic pigs (1.1%, 95% CI 0.2\u20132.5). The prevalence in high-income countries (15.7%, 95% CI 8.0\u201325.3) was significantly higher than that in middle- (0.8%, 95% CI 0.5\u20131.1), and low-income countries (0.1%, 95% CI 0.0\u20130.2). The prevalence was highest in finishing pigs at 4.9% (95% CI 0.9\u201311.0), and lowest among suckling pigs at 0% (95% CI 0.0\u20130.5).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold>The<jats:italic>Brucella<\/jats:italic>prevalence in pig herds currently is distributed widely throughout the world. In some countries, swine brucellosis may be a neglected zoonotic disease. We recommend long-term monitoring of the prevalence of brucellosis in domestic and wild pig herds. Attention should also be paid to animal welfare on intensive pig farms; controlling the breeding density may play an important role in reducing the spread of brucellosis among pigs.<\/jats:p>","DOI":"10.3389\/fvets.2021.630960","type":"journal-article","created":{"date-parts":[[2021,5,7]],"date-time":"2021-05-07T05:59:47Z","timestamp":1620367187000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":22,"title":["Global Comprehensive Literature Review and Meta-Analysis of Brucella spp. in Swine Based on Publications From 2000 to 2020"],"prefix":"10.3389","volume":"8","author":[{"given":"Qing-Long","family":"Gong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Han","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Ming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui-Yang","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Yang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Leng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,5,7]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.tmaid.2017.03.006","article-title":"Boar hunting and brucellosis caused by Brucella suis","volume":"16","author":"Franco-Paredes","year":"2017","journal-title":"Travel Med Infect Dis"},{"key":"B2","doi-asserted-by":"publisher","first-page":"e0007509","DOI":"10.1371\/journal.pntd.0007509","article-title":"Comparative performance of lateral flow immunochromatography, iELISA and Rose Bengal tests for the diagnosis of cattle, sheep, goat and swine brucellosis","volume":"13","author":"Gusi","year":"2019","journal-title":"PLoS Negl Trop Dis."},{"key":"B3","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1111\/tbed.12425","article-title":"Molecular survey on brucellosis in rodents and shrews - natural reservoirs of novel Brucella species in Germany?","volume":"64","author":"Hammerl","year":"2017","journal-title":"Transbound Emerg Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.prevetmed.2018.10.002","article-title":"Animal brucellosis control or eradication programs worldwide: a systematic review of experiences and lessons learned","volume":"160","author":"Zhang","year":"2018","journal-title":"Prev Vet Med."},{"key":"B5","doi-asserted-by":"publisher","first-page":"151","DOI":"10.3389\/fvets.2019.00151","article-title":"Canine brucellosis: Insights into the epidemiologic situation in Europe","volume":"6","author":"Buhmann","year":"2019","journal-title":"Front Vet Sci."},{"key":"B6","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.cvsm.2019.02.013","article-title":"Canine brucellosis: old foe and reemerging scourge","volume":"49","author":"Kauffman","year":"2019","journal-title":"Vet Clin North Am Small Anim Pract."},{"key":"B7","doi-asserted-by":"publisher","first-page":"3179","DOI":"10.2169\/internalmedicine.2961-19","article-title":"Chronic brucellosis in Japan","volume":"58","author":"Kawakami","year":"2019","journal-title":"Intern Med."},{"key":"B8","doi-asserted-by":"publisher","first-page":"5598","DOI":"10.2174\/0929867325666180510125009","article-title":"Research progress on brucellosis","volume":"26","author":"Deng","year":"2018","journal-title":"Curr Med Chem."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1016\/j.ajpath.2015.03.003","article-title":"Pathogenesis and immunobiology of brucellosis: review of Brucella-host interactions","volume":"185","author":"de Figueiredo","year":"2015","journal-title":"Am J Pathol."},{"key":"B10","volume-title":"Construction and evaluation of the immunogenicity of Brucella S2- BCSP31 deletion strain for vaccine","author":"Liu","year":"2018"},{"key":"B11","doi-asserted-by":"publisher","first-page":"2325","DOI":"10.1056\/NEJMra050570","article-title":"Brucellosis","volume":"352","author":"Pappas","year":"2005","journal-title":"New Engl J Med"},{"key":"B12","doi-asserted-by":"publisher","first-page":"e469","DOI":"10.1016\/j.ijid.2009.06.031","article-title":"Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature","volume":"14","author":"Buzgan","year":"2010","journal-title":"Int J Infect Dis."},{"key":"B13","doi-asserted-by":"publisher","first-page":"462","DOI":"10.7589\/0090-3558-48.2.462","article-title":"A serosurvey for Brucella suis, classical swine fever virus, porcine circovirus type 2, and pseudorabies virus in feral swine (Sus scrofa) of eastern North Carolina","volume":"48","author":"Sandfoss","year":"2012","journal-title":"J Wildl Dis"},{"key":"B14","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s13028-018-0373-9","article-title":"Seroprevalence of Brucella suis in eastern Latvian wild boars (Sus scrofa)","volume":"60","author":"Grantina-Ievina","year":"2018","journal-title":"Acta Vet Scand."},{"key":"B15","doi-asserted-by":"publisher","first-page":"20","DOI":"10.16863\/j.cnki.1003-6377.2012.03.005","article-title":"Research of prevention technology and prevalent in livestock brucellosis in Xinjiang (In Chinese)","volume":"3","author":"Li","year":"2012","journal-title":"Grass-Feeding Livestock"},{"key":"B16","doi-asserted-by":"publisher","first-page":"321","DOI":"10.3389\/fvets.2019.00321","article-title":"Brucellosis in Colombia: Current status and challenges in the control of an endemic disease","volume":"6","author":"Avila-Granados","year":"2019","journal-title":"Front Vet Sci"},{"key":"B17","doi-asserted-by":"publisher","first-page":"151","DOI":"10.21307\/pjm-2018-029","article-title":"Brucella -Virulence Factors, Pathogenesis and Treatment","volume":"67","author":"Acka","year":"2018","journal-title":"Pol J Microbiol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1177\/104063870701900301","article-title":"Diagnostic characterization of a feral swine herd enzootically infected with Brucella","volume":"19","author":"Stoffregen","year":"2007","journal-title":"J Vet Diagn Invest"},{"key":"B19","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.meegid.2016.04.012","article-title":"A genome-wide SNP-based phylogenetic analysis distinguishes different biovars of Brucella suis","volume":"41","author":"Sankarasubramanian","year":"2016","journal-title":"Infect Genet Evol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"e04960","DOI":"10.2903\/j.efsa.2017.4960","article-title":"Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016\/429): paratuberculosis","volume":"15","author":"More","year":"2017","journal-title":"Efsa J"},{"key":"B21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2147\/VMRR.S91360","article-title":"Swine brucellosis: current perspectives","volume":"8","author":"Olsen","year":"2016","journal-title":"Vet Med."},{"key":"B22","first-page":"672","article-title":"Brucella suis biovar 2 isolations from cattle in Poland","volume":"20","author":"Szulowski","year":"2013","journal-title":"Ann Agric Environ Med"},{"key":"B23","doi-asserted-by":"publisher","first-page":"353876","DOI":"10.1155\/2014\/353876","article-title":"Assessment of genetic diversity of zoonotic Brucella spp","volume":"2014","author":"Menshawy","year":"2014","journal-title":"recovered from livestock in Egypt using multiple locus VNTR analysis Biomed Res Int"},{"key":"B24","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/s40249-017-0296-0","article-title":"Multi-locus variable-number tandem repeat analysis of Chinese Brucella strains isolated from 1953 to 2013","volume":"6","author":"Tian","year":"2017","journal-title":"Infect Dis Poverty"},{"key":"B25","doi-asserted-by":"publisher","first-page":"e0213689","DOI":"10.1371\/journal.pone.0213689","article-title":"Distribution of Brucella field strains isolated from livestock, wildlife populations, and humans in Italy from 2007 to 2015","volume":"14","author":"De Massis","year":"2019","journal-title":"PLoS One"},{"key":"B26","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1186\/s12866-019-1665-6","article-title":"Investigation of the molecular characteristics of Brucella isolates from Guangxi province, China","volume":"19","author":"Liu","year":"2019","journal-title":"BMC Microbiol"},{"key":"B27","first-page":"350","article-title":"Analysis on brucellosis epidemiological characteristics in Hainan province","volume":"40","author":"Wang","year":"2019","journal-title":"Chin J Epidemiol"},{"key":"B28","first-page":"233","article-title":"Brucellosis in humans\u2013etiology, diagnostics, clinical forms","volume":"20","author":"Gali\u0144ska","year":"2013","journal-title":"Ann Agric Environ Med"},{"key":"B29","doi-asserted-by":"publisher","first-page":"5712920","DOI":"10.1155\/2018\/5712920","article-title":"A systematic review and meta-analysis of epidemiology and clinical manifestations of human brucellosis in China","volume":"2018","author":"Zheng","year":"2018","journal-title":"Biomed Res Int"},{"key":"B30","doi-asserted-by":"publisher","first-page":"100041","DOI":"10.1016\/j.jvacx.2019.100041","article-title":"Vaccine safety studies of Brucella abortus S19 and S19\u0394vjbR in pregnant swine","volume":"3","author":"Zriba","year":"2019","journal-title":"Vaccine X"},{"key":"B31","volume-title":"Treatment of Human Brucellosis \u2014 Review of Evidence from Clinical","author":"Sol\u00eds","year":"2015"},{"key":"B32","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/s12917-019-1800-5","article-title":"Transboundary spread of pig diseases: the role of international trade and travel","volume":"15","author":"Beltran-Alcrudo","year":"2019","journal-title":"BMC Vet Res"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.13806","article-title":"Prevalence of Cryptosporidium in pigs in China: A systematic review and meta-analysis","author":"Wang","year":"2020","journal-title":"Transbound Emerg Dis"},{"key":"B34","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.actatropica.2018.10.002","article-title":"Brucellosis seroprevalence in dairy cattle in China during 2008-2018: A systematic review and meta-analysis","volume":"189","author":"Ran","year":"2019","journal-title":"Acta Trop"},{"key":"B35","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1136\/jech-2013-203104","article-title":"Meta-analysis of prevalence","volume":"67","author":"Barendregt","year":"2013","journal-title":"J Epidemiol Commun H"},{"key":"B36","doi-asserted-by":"publisher","first-page":"104707","DOI":"10.1016\/j.prevetmed.2019.104707","article-title":"Bovine cysticercosis in Ethiopia: A systematic review and meta-analysis of prevalence from abattoir-based surveys","volume":"169","author":"Assefa","year":"2019","journal-title":"Prev Vet Med"},{"key":"B37","doi-asserted-by":"publisher","first-page":"105083","DOI":"10.1016\/j.prevetmed.2020.105083","article-title":"Prevalence of Haemophilus parasuis \u201cGlaesserella parasuis\u201d in pigs in China: A systematic review and meta-analysis","volume":"182","author":"Ni","year":"2020","journal-title":"Prev Vet Med"},{"key":"B38","doi-asserted-by":"publisher","first-page":"103908","DOI":"10.1016\/j.micpath.2019.103908","article-title":"Mink Aleutian disease seroprevalence in China during 1981-2017: A systematic review and meta-analysis","volume":"139","author":"Gong","year":"2020","journal-title":"Microb Pathog"},{"key":"B39","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.ijsu.2010.02.007","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"8","author":"Moher","year":"2010","journal-title":"Int J Surg"},{"key":"B40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst Rev"},{"key":"B41","doi-asserted-by":"publisher","first-page":"g7647","DOI":"10.1136\/bmj.g7647","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation","volume":"350","author":"Shamseer","year":"2015","journal-title":"BMJ"},{"key":"B42","doi-asserted-by":"publisher","first-page":"119","DOI":"10.2174\/1874318801004010119","article-title":"Clinical manifestations of brucellosis in domestic animals and humans","volume":"4","author":"Megid","year":"2010","journal-title":"Open Vet Sci J"},{"key":"B43","first-page":"625","article-title":"Veterinary medicine: a textbook of the diseases of cattle, sheep, pigs, goats and horses","volume":"20","author":"Radostits","year":"1994","journal-title":"J Equine Vet Sci."},{"key":"B44","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S2221-1691(11)60190-1","article-title":"A survey of zoonotic diseases in trade cattle slaughtered at Tanga city abattoir: a cause of public health concern","volume":"2","author":"Swai","year":"2012","journal-title":"Asian Pac J Trop Biomed."},{"key":"B45","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1017\/S0950268815002575","article-title":"Systematic review of brucellosis in the middle east: disease frequency in ruminants and humans and risk factors for human infection","volume":"144","author":"Musallam","year":"2016","journal-title":"Epidemiol Infect."},{"key":"B46","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1186\/s12889-017-5016-y","article-title":"Brucellosis remains a neglected disease in the developing world: a call for interdisciplinary action","volume":"18","author":"Franc","year":"2018","journal-title":"BMC Public Health."},{"key":"B47","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.prevetmed.2015.03.013","article-title":"Economic losses occurring due to brucellosis in Indian livestock populations","volume":"119","author":"Singha","year":"2015","journal-title":"Prev Vet Med."},{"key":"B48","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1016\/j.vetmic.2014.05.031","article-title":"Genetic relatedness of Brucella suis biovar 2 isolates from hares, wild boars and domestic pigs","volume":"27","author":"Kreizinger","year":"2014","journal-title":"Vet Microbiol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/S1473-3099(06)70382-6","article-title":"The new global map of human brucellosis","volume":"6","author":"Pappas","year":"2006","journal-title":"Lancet Infect Dis."},{"key":"B50","doi-asserted-by":"publisher","first-page":"249","DOI":"10.20506\/rst.32.1.2197","article-title":"Economics of brucellosis impact and control in low-income countries","volume":"32","author":"McDermott","year":"2013","journal-title":"Rev Sci Tech."},{"key":"B51","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/S0378-1135(02)00217-1","article-title":"Brucellosis in the European Union and Norway at the turn of the twenty-first century","volume":"90","author":"Godfroid","year":"2002","journal-title":"Vet Microbiol."},{"key":"B52","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/S0378-1135(02)00233-X","article-title":"Brucella vaccines in wildlife","volume":"90","author":"Davis","year":"2002","journal-title":"Vet Microbiol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.3201\/eid1108.041197","article-title":"Laboratory exposures to brucellae and implications for bioterrorism","volume":"11","author":"Yagupsky","year":"2005","journal-title":"Emerg Infect Dis."},{"key":"B54","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/1746-6148-8-80","article-title":"A serological and bacteriological survey of brucellosis in wild boar (Sus scrofa) in Belgium","volume":"8","author":"Gr\u00e9goire","year":"2012","journal-title":"BMC Vet Res."},{"key":"B55","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.2460\/javma.1995.207.10.1332","article-title":"Comparison of serologic tests and bacteriologic culture for detection of brucellosis in swine from naturally infected herds","volume":"207","author":"Ferris","year":"1995","journal-title":"J Am Vet Med Assoc."},{"key":"B56","first-page":"263","article-title":"Brucella suis biotype 2 infection of wild boars (Sus scrofa) in Belgium","volume":"138","author":"Godfroid","year":"1994","journal-title":"Ann Med Vet."},{"key":"B57","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1556\/avet.51.2003.4.4","article-title":"Wild boars (Sus scrofa) as reservoirs of Brucella suis biovar 2 in Croatia","volume":"51","author":"Cvetnic","year":"2003","journal-title":"Acta vet Hung."},{"key":"B58","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1136\/vr.160.11.362","article-title":"Prevalence of classical swine fever, Aujeszky's disease and brucellosis in a population of wild boar in Switzerland","volume":"160","author":"Leuenberger","year":"2007","journal-title":"Vet Rec."},{"key":"B59","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1136\/vr.c5927","article-title":"Brucella species antibodies and isolation in wild boar in north-east Spain","volume":"167","author":"Closa-Sebasti\u00e0","year":"2010","journal-title":"Vet Rec."},{"key":"B60","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/1471-2334-10-46","article-title":"Spatial distribution and risk factors of brucellosis in Iberian wild ungulates","volume":"10","author":"Mu\u00f1oz","year":"2010","journal-title":"BMC Infect Dis."},{"key":"B61","doi-asserted-by":"publisher","first-page":"868","DOI":"10.7589\/0090-3558-47.4.868","article-title":"Free-ranging wild boar: a disease threat to domestic pigs in Switzerland?","volume":"47","author":"Wu","year":"2011","journal-title":"J Wildl Dis."},{"key":"B62","first-page":"1","article-title":"Brucellose du porc domestique et du sanglier sauvage due ?? Brucella suis biovar 2 en France","volume":"38","author":"Garin-Bastuji","year":"2000","journal-title":"Epid\u00e9miol Sant\u00e9 Anim."},{"key":"B63","doi-asserted-by":"publisher","first-page":"3","DOI":"10.17221\/5805-VETMED","article-title":"Serological survey of the wild boar (Sus scrofa) for tularaemia and brucellosis in South Moravia, Czech Republic","volume":"47","author":"Hub\u00e1lek","year":"2002","journal-title":"Vet Med."},{"key":"B64","doi-asserted-by":"publisher","first-page":"115","DOI":"10.17221\/5684-VETMED","article-title":"Brucellosis in wild boar (Sus scrofa) in the republic of Croatia","volume":"49","author":"Cvetnic","year":"2004","journal-title":"Vet Med."},{"key":"B65","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1051\/vetres:2005003","article-title":"From the discovery of the Malta fever's agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis","volume":"36","author":"Godfroid","year":"2005","journal-title":"Vet Res."},{"key":"B66","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/1751-0147-53-24","article-title":"Cattle brucellosis in traditional livestock husbandry practice in Southern and Eastern Ethiopia, and its zoonotic implication","volume":"53","author":"Megersa","year":"2011","journal-title":"Acta Vet Scand."},{"key":"B67","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s11250-017-1242-7","article-title":"Brucellosis and associated risk factors in dairy cattle of eastern Ethiopia","volume":"49","author":"Terefe","year":"2017","journal-title":"Trop Anim Health Prod."},{"key":"B68","doi-asserted-by":"publisher","first-page":"2073","DOI":"10.1007\/s11250-018-1631-6","article-title":"Seroprevalence of bovine brucellosis and associated risk factors in Nakasongola district, Uganda","volume":"51","author":"Bugeza","year":"2019","journal-title":"Trop Anim Health Prod."},{"key":"B69","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/s0167-5877(00)00152-5","article-title":"Risk factors for Brucella spp. infection in dairy cattle farms in Asmara, State of Eritrea","volume":"46","author":"Omer","year":"2000","journal-title":"Pre Vet Med"},{"key":"B70","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s11250-009-9382-z","article-title":"Sero-prevalence of bovine brucellosis and its risk factors in Jimma zone of Oromia Region, South-western Ethiopia","volume":"42","author":"Ibrahim","year":"2010","journal-title":"Trop Anim Health Prod."},{"key":"B71","doi-asserted-by":"publisher","first-page":"105241","DOI":"10.1016\/j.actatropica.2019.105241","article-title":"The prevalence of Brucella spp. In dairy products in the middle east region: a systematic review and meta-analysis","volume":"202","author":"Abedi","year":"2019","journal-title":"Acta Trop."},{"key":"B72","doi-asserted-by":"publisher","first-page":"66","DOI":"10.4038\/cmj.v52i2.1028","article-title":"Brucellosis in humans and animals","volume":"52","author":"Goonaratna","year":"2009","journal-title":"Ceylon Med J."},{"key":"B73","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1007\/s11250-012-0108-2","article-title":"Brucellosis due to Brucella suis in a swine herd associated with a human clinical case in the State of S\u00e3o Paulo, Brazil","volume":"44","author":"Meirelles-Bartoli","year":"2012","journal-title":"Trop Anim Health Prod."},{"key":"B74","doi-asserted-by":"publisher","first-page":"151","DOI":"10.12834\/VetIt.50.3384.1","article-title":"First report of Brucella suis biovar 2 in a semi free-range pig farm, Italy","volume":"51","author":"Barlozzari","year":"2015","journal-title":"Vet Ital."},{"key":"B75","doi-asserted-by":"publisher","first-page":"2170","DOI":"10.1017\/S0950268814003513","article-title":"Brucella suis infection in domestic pigs in Sardinia (Italy)","volume":"143","author":"Pilo","year":"2015","journal-title":"Epidemiol Infect."},{"key":"B76","doi-asserted-by":"publisher","first-page":"e00618","DOI":"10.1128\/genomeA.00618-14","article-title":"Complete genome sequences of three iberian Brucella suis Biovar 2 strains isolated from wild boars","volume":"2","author":"Ferreira","year":"2014","journal-title":"Genome Announc."},{"key":"B77","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/s10344-006-0072-0","article-title":"A serological study on brucellosis in wild boars in Germany","volume":"53","author":"Melzer","year":"2006","journal-title":"Eur J Wildlife Res."},{"key":"B78","doi-asserted-by":"publisher","first-page":"523","DOI":"10.20506\/rst.29.3.1994","article-title":"Animal production food safety: priority pathogens for standard setting by the world organisation for animal health","volume":"29","author":"Knight-Jones","year":"2010","journal-title":"Rev Sci Tech."},{"key":"B79","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.vetmic.2006.11.003","article-title":"Aujeszky's disease virus infection patterns in European wild boar","volume":"120","author":"Ruiz-Fons","year":"2007","journal-title":"Vet Microbiol."},{"key":"B80","volume-title":"Ecolog\u00eda del Jabal\u00ed en Do\u00f1ana: Par\u00e1metros Reproductivose Impacto Ambiental","author":"Llario","year":"1996"},{"key":"B81","doi-asserted-by":"publisher","first-page":"777","DOI":"10.20506\/rst.13.3.795","article-title":"Epidemiology of bovine brucellosis in mali: serologic investigation and initial isolation of strains of Brucella abortus","volume":"13","author":"Tounkara","year":"1994","journal-title":"Rev Sci Tech."},{"key":"B82","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/tbed.12206","article-title":"An assessment of zoonotic and production limiting pathogens in rusa deer (Cervus timorensis rusa) from Mauritius","volume":"61","author":"Jori","year":"2014","journal-title":"Transbound Emerg Dis."}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2021.630960\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T09:32:46Z","timestamp":1725010366000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2021.630960\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,7]]},"references-count":82,"alternative-id":["10.3389\/fvets.2021.630960"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2021.630960","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,7]]},"article-number":"630960"}}