{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T20:32:16Z","timestamp":1771619536558,"version":"3.50.1"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T00:00:00Z","timestamp":1612483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>This is a case of<jats:italic>Conidiobolus lamprauges<\/jats:italic>rhinitis in a Goldendoodle, that was presented for evaluation of sneezing, coughing, lethargy, as well as right-sided epistaxis and clear ocular discharge. Computed tomography revealed a large amount of soft tissue within the right nasal passage that obscured the osseous turbinates from the right maxillary canine tooth to the right side of the choanae. Biopsies revealed eosinophilic granulomas with variable number of basophilic to negatively staining, septate, fungal hyphae with non-parallel walls and irregular branching that were subsequently determined to be<jats:italic>Conidiobolus lamprauges<\/jats:italic>via panfungal PCR and sequencing. Complete and sustained resolution of clinical disease was achieved after 75 days of systemic antifungal therapy. This report describes for the first time, important clinical features of a dog with nasal conidiobolomycosis that will facilitate its recognition, prognostication, and treatment in clinical practice.<\/jats:p>","DOI":"10.3389\/fvets.2021.633695","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T13:52:08Z","timestamp":1612533128000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: Successful Management of Conidiobolus Lamprauges Rhinitis in a Dog"],"prefix":"10.3389","volume":"8","author":[{"given":"Jared A.","family":"Jaffey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric T.","family":"Hostnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline Rodrigues","family":"Hoffman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen","family":"Jay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvia H.","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan P.","family":"Wiederhold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,2,5]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1111\/j.1365-3164.1994.tb00032.x","article-title":"Canine subcutaneous zygomycosis caused by Conidiobolus sp","volume":"5","author":"Hillier","year":"1994","journal-title":"Vet Dermatol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.mmcr.2015.02.005","article-title":"Disseminated Conidiobolus incongruous in a dog: a case report and literature review","volume":"8","author":"Mackey","year":"2015","journal-title":"Med Mycol Case Rep"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1479","DOI":"10.1111\/j.1939-1676.2006.tb00769.x","article-title":"Treatment of Conidiobolus sp. pneumonia with itraconazole in a dog receiving immunosuppressive therapy","volume":"20","author":"Hawkins","year":"2006","journal-title":"J Vet Intern Med"},{"key":"B4","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1046\/j.1365-3164.1997.d01-9.x","article-title":"Oral conidiobolomycosis in a dog","volume":"8","author":"Bauer","year":"1997","journal-title":"Vet Dermatol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1016\/j.cmi.2016.04.005","article-title":"Entomophthoramycosis: a neglected tropical mycosis","volume":"22","author":"Shaikh","year":"2016","journal-title":"Clin Microbiol Infect"},{"key":"B6","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1177\/0300985817698207","article-title":"Panfungal polymerase chain reaction for identification of fungal pathogens in formalin-fixed animal tissues","volume":"54","author":"Meason-Smith","year":"2017","journal-title":"Vet Pathol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/0145561319892475","article-title":"Rhinofacial conidiobolomycosis: a case series and review of the literature","author":"Sigera","year":"2020","journal-title":"Ear Nose Throat J"},{"key":"B8","first-page":"230","article-title":"Disseminated zygomycosis caused by Conidiobolus incongruous in a deer","volume":"69","author":"Stephens","year":"1997","journal-title":"Aust Vet J"},{"key":"B9","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1111\/j.1574-6968.2009.01778.x","article-title":"Differential divergences of obligately insect-pathogenic Entomophthora species from fly and aphid hosts","volume":"300","author":"Jensen","year":"2009","journal-title":"FEMS Microbiol Lett"},{"key":"B10","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.jcpa.2012.12.002","article-title":"Pathology of nasal infection caused by Conidiobolus lamprauges and Pythium insidiosum in sheep","volume":"149","author":"Ubiali","year":"2013","journal-title":"J Comp Pathol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1016\/S0195-5616(03)00034-2","article-title":"Pythiosis, lagenidiosis, and zygomycosis in small animals","volume":"33","author":"Grooters","year":"2003","journal-title":"Vet Clin Small Anim"},{"key":"B12","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.micpath.2017.02.043","article-title":"Experimental infection in gerbils by Conidiobolus lamprauges","volume":"105","author":"de","year":"2017","journal-title":"Microb Pathog"},{"key":"B13","doi-asserted-by":"publisher","first-page":"E15; 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