{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T16:19:36Z","timestamp":1782922776057,"version":"3.54.5"},"reference-count":32,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T00:00:00Z","timestamp":1671667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>Rabies is a fatal encephalitis caused by the rabies virus. The diagnosis of the disease depends in large part on the exposure history of the victim and clinical manifestations of the disease. Rapid rabies diagnosis is an important step in its prevention and control. Therefore, for accurate and timely diagnosis and prevention of rabies, we developed nanomaterials for a novel photoelectrochemical biosensing approach (PBA) for the rapid and reliable diagnosis of rabies virus. This approach uses high-efficiency exciton energy transfer between cadmium telluride quantum dots and Au nanoparticles and is low cost, and easy to miniaturize. By constructing PBA, rabies virus can be detected quickly and with a high degree of sensitivity and specificity; the minimum detection concentration limit for rabies virus is approximately 2.16 ffu\/mL of rabies virus particles, or 2.53 \u00d7 10<jats:sup>1<\/jats:sup> fg\/mL of rabies virus RNA. PBA could also detect rabies virus in the brain and lung tissue from rabid dogs and mice with better sensitivity than RT-PCR.<\/jats:p>","DOI":"10.3389\/fvets.2022.1079916","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T07:02:36Z","timestamp":1671692556000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Detection of rabies virus via exciton energy transfer between CdTe quantum dots and Au nanoparticles"],"prefix":"10.3389","volume":"9","author":[{"given":"Yan-Juan","family":"Liao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duo-Duo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zong-Ling","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Ling","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Yun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraha Bahlbi","family":"Kiflu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zai Yin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Ning","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting Rong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,12,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2508","DOI":"10.1056\/NEJMoa050382","article-title":"Survival after treatment of rabies with induction of coma","volume":"352","author":"Willoughby","year":"2005","journal-title":"N Engl J Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1111\/zph.12745","article-title":"Detection of rabies virus antigen by the indirect rapid immunohistochemistry test in equines and comparisons with other diagnostic techniques","volume":"67","author":"Torquato","year":"2020","journal-title":"Zoonoses Public Health."},{"key":"B3","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.antiviral.2013.03.004","article-title":"Potential economic benefits of eliminating canine rabies","volume":"98","author":"Shwiff","year":"2013","journal-title":"Antiviral Res."},{"key":"B4","doi-asserted-by":"publisher","first-page":"66","DOI":"10.2460\/javma.256.1.66","article-title":"Evaluation of rabies virus characterization to enhance early detection of important rabies epizootic events in the United States","volume":"256","author":"Pieracci","year":"2020","journal-title":"Am Vet Med Assoc."},{"key":"B5","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1177\/1040638718818223","article-title":"Evaluation of six Taqman RT-RTPCR kits on two thermocyclers for the reliable detection of rabies virus RNA","volume":"31","author":"Picard-Meyer","year":"2019","journal-title":"J Vet Diagn Invest."},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2016.03.016","article-title":"Laboratory diagnostics in dog-mediated rabies: an overview of performance and a proposed strategy for various settings","author":"Duong","year":"2016","journal-title":"Int. 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