{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T17:49:36Z","timestamp":1770227376999,"version":"3.49.0"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T00:00:00Z","timestamp":1647993600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>A 14-year-old male neutered domestic short-hair cat was presented for a history of behavioral changes and episodes of urinary retention. Neurological examination was consistent with a multifocal intracranial neuroanatomical localization, with suspected right sided lateralisation and suspected raised intracranial pressure (ICP). Brain magnetic resonance imaging (MRI) revealed an intraventricular multilobulated well-defined T2W-hyperintense and T1W-isointense, markedly contrast enhancing mass lesion within the dorsal aspect of the III ventricle extending into the left lateral ventricle, causing hypertensive obstructive hydrocephalus. A ventriculoperitoneal shunt (VPS) was placed within the left lateral ventricle, followed by a radiation therapy (RT) course of 45 Gy total dose in 18 daily fractions. Six-months post-RT, computed tomography revealed mild reduction in mass size and resolution of the hydrocephalus. The patient was neurologically normal with no medical treatment. Raised ICP causes severe clinical signs, can lead to brain ischaemia and herniation, and significantly increases anesthetic risk during RT. Placement of a VPS in cats with hypertensive obstructive hydrocephalus may allow improvement of neurological signs due to raised ICP, and therefore making the patient a more stable candidate for anesthesia and radiation therapy.<\/jats:p>","DOI":"10.3389\/fvets.2022.828083","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T06:48:08Z","timestamp":1648536488000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: Ventriculoperitoneal Shunting and Radiation Therapy Treatment in a Cat With a Suspected Choroid Plexus Tumor and Hypertensive Hydrocephalus"],"prefix":"10.3389","volume":"9","author":[{"given":"Elizabeth","family":"Mahon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldara","family":"Eiras-Diaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Mason","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Stabile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ane","family":"Uriarte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,3,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1177\/1098612X18801032","article-title":"Radiation Therapy for Intracranial Tumours in Cats with Neurological Signs","volume":"21","author":"K\u00f6rner","year":"2019","journal-title":"J Feline Med Surg."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1556","DOI":"10.1111\/jvim.15818","article-title":"Palliative ventriculoperitoneal shunting in dogs with obstructive hydrocephalus caused by tumors affecting the third ventricle","volume":"34","author":"Orlandi","year":"2020","journal-title":"J Vet Intern Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/j.1532-950X.2010.00764.x","article-title":"Surgical technique, postoperative complications and outcome in 14 dogs treated for hydrocephalus by ventriculoperitoneal shunting","volume":"40","author":"Stefani","year":"2011","journal-title":"Vet Surg."},{"key":"B4","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1111\/vru.12464","article-title":"Magnetic resonance imaging features of intraventricular ependymomas in five cats","volume":"58","author":"DeJesus","year":"2017","journal-title":"Vet Radiol Ultrasound."},{"key":"B5","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1111\/j.1939-1676.2007.tb02975.x","article-title":"ACVIM consensus statement","volume":"21","author":"Cou\u00ebtil","year":"2007","journal-title":"J Vet Intern Med."},{"key":"B6","doi-asserted-by":"publisher","first-page":"525","DOI":"10.2460\/ajvr.79.5.525","article-title":"Effect of blood contamination on results of dipstick evaluation and urine protein-to-urine creatinine ratio for urine samples from dogs and cats","volume":"79","author":"Vient\u00f3s-Plotts","year":"2018","journal-title":"Am J Vet Res."},{"key":"B7","volume-title":"A Practical Guide to Feline and Canine Neurology","author":"Dewey","year":"2008"},{"key":"B8","doi-asserted-by":"publisher","first-page":"181","DOI":"10.5326\/JAAHA-MS-6570","article-title":"2016 AAHA Oncology Guidelines for Dogs and Cats","volume":"52","author":"Biller","year":"2016","journal-title":"J Am Anim Hosp Assoc."},{"key":"B9","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1111\/j.1939-1676.2003.tb02525.x","article-title":"Feline intracranial neoplasia: retrospective review of 160 cases (1985\u20132001)","volume":"17","author":"Troxel","year":"2003","journal-title":"J Vet Intern Med."},{"key":"B10","doi-asserted-by":"publisher","first-page":"29","DOI":"10.4103\/1793-5482.110277","article-title":"Choroid plexus tumors: a clinico-pathological and neuro-radiological study of 23 cases","volume":"8","author":"Jaiswal","year":"2013","journal-title":"Asian J Neurosurg."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.3892\/mco.2015.627","article-title":"Role of ventriculoperitoneal shunting in patients with neoplasms of the central nervous system: an analysis of 59 cases","volume":"3","author":"Nigim","year":"2015","journal-title":"Mol Clin Oncol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1111\/jvim.15468","article-title":"Association between improvement of clinical signs and decrease of ventricular volume after ventriculoperitoneal shunting in dogs with internal hydrocephalus","volume":"33","author":"Schmidt","year":"2019","journal-title":"J Vet Int Med."},{"key":"B13","article-title":"BSAVA manual of canine and feline neurology. 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