{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:38:22Z","timestamp":1780619902569,"version":"3.54.1"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T00:00:00Z","timestamp":1650585600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010677","name":"Instituto Nacional de Tecnolog\u00eda Agropecuaria","doi-asserted-by":"publisher","award":["PNSA 1115057"],"award-info":[{"award-number":["PNSA 1115057"]}],"id":[{"id":"10.13039\/501100010677","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>Aujeszky's disease (AD) is endemic in Argentina. In 2016, an inactivated gE- negative marker Bartha K61 vaccine (AUSKIPRA<jats:sup>\u00ae<\/jats:sup> BK) was launched for use, making Argentina the only country to carry out a control strategy plan with it. In the present article, we describe the results of a control program in a farrow-to-finishing farm with high initial AD prevalence (33% in sows), based on the systematic vaccination, detection, and elimination of seropositive pigs, the replacement of sows with vaccinated gilts, and the instauration of artificial insemination. The program was suitable for diminishing the incidence and the prevalence at levels consistent with virus eradication. This situation has been sustained over time. This is the first report of AUSKIPRA<jats:sup>\u00ae<\/jats:sup> BK efficacy under field conditions.<\/jats:p>","DOI":"10.3389\/fvets.2022.852650","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T06:28:52Z","timestamp":1650608932000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Assessment of an Aujeszky's Disease Control Strategy in a Highly Prevalent Pig Farm Based on Systematic Vaccination With an Inactivated gE-Negative Marker Vaccine"],"prefix":"10.3389","volume":"9","author":[{"given":"Mar\u00eda N.","family":"Aznar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando A.","family":"Bessone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Segurado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio J.","family":"Duffy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,4,22]]},"reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0168-1656(95)00129-8","article-title":"The use of marker vaccines in eradication of herpesviruses","volume":"44","author":"van Oirschot","year":"1996","journal-title":"J Biotechnol."},{"key":"B2","first-page":"471","article-title":"Evidence of long distance airborne transmission of Aujeszky's disease (pseudorabies) virus","volume":"127","author":"Christensen","year":"1990","journal-title":"Vet Rec."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40813-020-00181-z","article-title":"Biosecurity in pig farms: a review","volume":"7","author":"Alarc\u00f3n","year":"2021","journal-title":"BMC Porc Heal Manag."},{"key":"B4","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1136\/inpract.27.5.230","article-title":"Biosecurity: reducing disease risks to pig breeding herds","volume":"27","author":"Pritchard","year":"2005","journal-title":"Farm Anim Pract."},{"key":"B5","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1079\/ahr200479","article-title":"Application of DIVA vaccines and their companion diagnostic tests to foreign animal disease eradication","volume":"5","author":"Pasick","year":"2004","journal-title":"Anim Health Res Rev."},{"key":"B6","first-page":"3","article-title":"Aujeszky's disease vaccination and differentiation of vaccinated from infected pigs","volume":"119","author":"Pensaert","year":"2004","journal-title":"Dev Biol (Basel)."},{"key":"B7","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1080\/01652176.1985.9693982","article-title":"Vaccines against Aujeszky's disease: EV|aluation of their efficacy under standardized laboratory conditions","volume":"7","author":"de Leeuw","year":"1985","journal-title":"Vet Q"},{"key":"B8","unstructured":"Primer diagn\u00f3stico de la enfermedad de Aujeszky en cerdos en la Rep\u00fablica Argentina5864\n            AmbrogiA.\n            GiraudoJ\n            BussoJ\n            BiancoO\n            BagnatE\n            Segura de AramburuM\n          \n            TomoXLII\n          Gaceta Veterinaria1981"},{"key":"B9","article-title":"Senasa","year":"2009"},{"key":"B10","first-page":"66","article-title":"El jabal\u00ed (Sus Scrofa) como reservorio de Enfermedad de Aujeszky en Patagonia Noreste: resultados preliminares","volume":"53","author":"Abate","year":"2015","journal-title":"Revista Colegio de Veterinarios de la Provincia de Buenos Aires."},{"key":"B11","doi-asserted-by":"publisher","first-page":"21","DOI":"10.24215\/15142590e004","volume":"37","author":"Carpinetti","year":"2017","journal-title":"Analecta Ve"},{"key":"B12","volume-title":"Practical Field Experience of How to Control and Eradicate Pseudorabies on a Commercial Farm in China","author":"Liu","year":"2019"},{"key":"B13","volume-title":"Efficacy of a Novel Vaccination Program in a PRV Infected Farm","author":"Ning","year":"2019"},{"key":"B14","volume-title":"Production of Pseudorabies-Free Gilts by a Combined Vaccination Program With Modified Live and Inactivated Vaccines","author":"Yang","year":"2019"},{"key":"B15","unstructured":""},{"key":"B16","volume-title":"Le porc par les chiffres 2018 - 2019: la fili\u00e8re porcine en France, dans l'UE et le monde","year":"2018"},{"key":"B17","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0378-1135(96)01297-7","article-title":"Aujeszky's disease and the European Community","volume":"55","author":"Moynagh","year":"1997","journal-title":"Vet. Microbiol."},{"key":"B18","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0378-1135(96)01301-6","article-title":"Aujeszky ' s disease (pseudorabies) virus eradication campaign in the Netherlands","volume":"55","author":"Stegeman","year":"1997","journal-title":"Vet Microbiol"},{"key":"B19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1135(96)01298-9","article-title":"Eradication and control programmes against Aujeszky's disease (pseudorabies) in France","volume":"55","author":"Vannier","year":"1997","journal-title":"Vet. Microbiol."}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2022.852650\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T06:29:08Z","timestamp":1650608948000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2022.852650\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,22]]},"references-count":19,"alternative-id":["10.3389\/fvets.2022.852650"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2022.852650","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,22]]},"article-number":"852650"}}