{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:00:14Z","timestamp":1785841214157,"version":"3.56.0"},"reference-count":62,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T00:00:00Z","timestamp":1660780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to compare the effects of a sustained inflation alveolar recruiting maneuver (ARM) followed by 5 cmH<jats:sub>2<\/jats:sub>O of PEEP and a stepwise ARM, in dogs undergoing laparoscopic surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Twenty adult dogs were enrolled in this prospective randomized clinical study. Dogs were premedicated with methadone intramuscularly (IM); anesthesia was induced with propofol intravenously (IV) and maintained with inhaled isoflurane in pure oxygen. The baseline ventilatory setting (BVS) was as follows: tidal volume of 15 mL\/kg, inspiratory pause of 25%, inspiratory to expiratory ratio of 1:2, and the respiratory rate to maintain the end-tidal carbon dioxide between 45 and 55 mmHg. 10 min after pneumoperitoneum, randomly, 10 dogs underwent sustained inflation ARM followed by 5 cmH<jats:sub>2<\/jats:sub>O of PEEP (ARMi), while 10 dogs underwent a stepwise recruitment maneuver followed by the setting of the \u201cbest PEEP\u201d (ARMc). Gas exchange, respiratory system mechanics, and hemodynamic were evaluated before the pneumoperitoneum induction (BASE), 10 min after the pneumoperitoneum (PP), 10 min after the recruitment (ARM), and 10 min after the pneumoperitoneum resolution (PostPP). Statistical analysis was performed with the ANOVA test (<jats:italic>p<\/jats:italic> &amp;lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Static compliance decreased in both groups at PP (ARMc = 1.35 \u00b1 0.21; ARMi = 1.16 \u00b1 0.26 mL\/cmH<jats:sub>2<\/jats:sub>O\/kg) compared to BASE (ARMc = 1.78 \u00b1 0.60; ARMi = 1.66 \u00b1 0.66 mL\/cmH<jats:sub>2<\/jats:sub>O\/kg) and at ARM (ARMc = 1.71 \u00b1 0.41; ARMi = 1.44 \u00b1 0.84 mL\/cmH<jats:sub>2<\/jats:sub>O\/kg) and PostPP (ARMc = 1.75 \u00b1 0.45; ARMi = 1.89 \u00b1 0.59 mL\/cmH<jats:sub>2<\/jats:sub>O\/kg), and it was higher compared to PP and similar to BASE. The PaO<jats:sub>2<\/jats:sub>\/FiO<jats:sub>2<\/jats:sub>, in both groups, was higher at ARM (ARMc = 455.11 \u00b1 85.90; ARMi = 505.40 \u00b1 31.70) and PostPP (ARMc = 521.30 \u00b1 66.20; ARMi = 450.90 \u00b1 70.60) compared to PP (ARMc = 369.53 \u00b1 49.31; ARMi = 394.32 \u00b1 37.72).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion and clinical relevance<\/jats:title><jats:p>The two ARMs improve lung function in dogs undergoing laparoscopic surgery similarly. Application of PEEP at the end of the ARMs prolonged the effects of the open-lung strategy.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fvets.2022.904673","type":"journal-article","created":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T14:06:31Z","timestamp":1660831591000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["Effects of two alveolar recruitment maneuvers in an \u201copen-lung\u201d approach during laparoscopy in dogs"],"prefix":"10.3389","volume":"9","author":[{"given":"Caterina","family":"Di Bella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Vicenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquin","family":"Araos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Lacitignola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Fracassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzia","family":"Stabile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Grasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Crovace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Staffieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,8,18]]},"reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"xiv","DOI":"10.1002\/9781118845912","volume-title":"2. 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