{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:36:25Z","timestamp":1753893385636,"version":"3.41.2"},"reference-count":8,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T00:00:00Z","timestamp":1659052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>This case documents a previously undescribed presentation of <jats:italic>Helicobacter<\/jats:italic> spp. gastritis. An 8-year-old female spayed golden retriever with chronic vomiting was found to have a cluster of multiple, round, well-defined, hypoechoic foci of varying sizes surrounded by gas within the lumen of the stomach on ultrasonographic examination. Further endoscopic examination revealed multiple raised mass-like lesions in the fundus on endoscopic examination. Histopathological findings were consistent with <jats:italic>Helicobacter<\/jats:italic> spp. infection. The dog was treated with both amoxicillin 400 mg and clarithromycin 180 mg BID for 21 days and omeprazole 20 mg SID for 34 days. After the treatment, the vomiting and fundic lesions were resolved on ultrasonographic examination. This case represents a novel gross morphologic presentation for <jats:italic>Helicobacter<\/jats:italic> spp. gastritis that responded to appropriate therapy and highlights how early intervention with advanced imaging can aid in diagnosis and treatment.<\/jats:p>","DOI":"10.3389\/fvets.2022.959526","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T07:15:15Z","timestamp":1659078915000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultrasonographic and endoscopic guidance in diagnosis of Helicobacter gastritis presenting as a mass lesion in a dog: A case report"],"prefix":"10.3389","volume":"9","author":[{"given":"Thomas","family":"Gomes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecelia","family":"Harmon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Nappier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,7,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"139","DOI":"10.4142\/jvs.2007.8.2.139","article-title":"Diagnosis of Helicobacter spp. infection in the canine stomach","volume":"8","author":"Prachasilpchai","year":"2007","journal-title":"J Vet Sci."},{"key":"B2","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1111\/j.1939-1676.1999.tb02203.x","article-title":"Gastric function in dogs with naturally acquired gastric Helicobacter spp. Infection","volume":"13","author":"Simpson","year":"1999","journal-title":"J Vet Intern Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1111\/j.1939-1676.2000.tb02225.x","article-title":"Helicobacter infection in dogs and cats: facts and fiction","volume":"14","author":"Neiger","year":"2000","journal-title":"J Vet Intern Med."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1111\/j.1939-1676.2007.tb01936.x","article-title":"Triple antimicrobial therapy and acid suppression in dogs with chronic vomiting and gastric Helicobacter spp","volume":"21","author":"Leib","year":"2007","journal-title":"J Vet Intern Med."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/MMBR.00001-18","article-title":"Helicobacter pylori biofilm formation and its potential role in pathogenesis","volume":"82","author":"Hathroubi","year":"2018","journal-title":"Microbiol Mol Biol Rev."},{"key":"B6","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1002\/jgh3.12049","article-title":"Nodular gastritis in association with gastric cancer development before and after Helicobacter pylori eradication","volume":"2","author":"Nishikawa","year":"2018","journal-title":"JGH Open."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.3390\/ani1105140","article-title":"Canine gastric carcinomas: a histopathological and immunohistochemical study and similarities with the human counterpart","volume":"11","author":"Hardas","year":"2021","journal-title":"Animals (Basel)."},{"key":"B8","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jcpa.2015.10.181","article-title":"Canine gastric pathology: a review","volume":"154","author":"Amorim","year":"2016","journal-title":"J Comp Pathol."}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2022.959526\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T07:15:19Z","timestamp":1659078919000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2022.959526\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,29]]},"references-count":8,"alternative-id":["10.3389\/fvets.2022.959526"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2022.959526","relation":{},"ISSN":["2297-1769"],"issn-type":[{"type":"electronic","value":"2297-1769"}],"subject":[],"published":{"date-parts":[[2022,7,29]]},"article-number":"959526"}}