{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:35:39Z","timestamp":1753893339286,"version":"3.41.2"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T00:00:00Z","timestamp":1687996800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The objective of this study was to investigate the effect of a novel screw type on stiffness and failure characteristics of a tibial plateau leveling osteotomy (TPLO) construct under cyclic loading conditions. The authors hypothesized that bone-screw-fasteners (BSF) would result in superior biomechanical stability compared with locking buttress screws (LBS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Twelve pairs of canine cadaveric pelvic limbs were included in this<jats:italic>ex vivo<\/jats:italic>biomechanical study. A TPLO was performed using a 3.5mm locking TPLO plate and stabilized using either LBS or BSF. Cyclic loading was performed for 30,000 cycles at 4Hz with a peak-load of 1000N (50N valley). The cyclic test was then continued by stepwise incremental increase of peak-load at a rate of 75N per 500 cycles until failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cycles to failure for LBS (44,260 \u00b1 5,770) and BSF (41,540 \u00b1 7,686) were not significantly different (<jats:italic>p<\/jats:italic>\u2009=\u20090.36). Maximum force for LBS (3,134 \u00b1 797N) and BSF (2,940 \u00b1 831N) was not significantly different either (<jats:italic>p<\/jats:italic>\u2009=\u20090.58). Dynamic stiffness for LBS (1,778 \u00b1 932 N\/mm) and BSF (1,574 \u00b1 677 N\/mm) was not significantly different (<jats:italic>p<\/jats:italic>\u2009=\u20090.58).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Stabilization of the TPLO with BSF provided similar biomechanical stability under cyclic axial loading conditions as the LBS. BSF may be an acceptable alternative to traditional locking screws for TPLO.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fvets.2023.1207563","type":"journal-article","created":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T09:47:49Z","timestamp":1688118469000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Ex vivo biomechanical evaluation of a bone-screw-fastener for tibial plateau leveling osteotomy"],"prefix":"10.3389","volume":"10","author":[{"given":"William S.","family":"Kettleman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael H.","family":"Jaffe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert W.","family":"Wills","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara J.","family":"Dietz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve H.","family":"Elder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,6,29]]},"reference":[{"key":"ref1","first-page":"1071","article-title":"Stifle joint","volume-title":"Veterinary surgery: small animal","author":"Kowaleski","year":"2018"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1016\/S0195-5616(93)50082-7","article-title":"Tibial plateau leveling osteotomy for repair of cranial cruciate ligament rupture in the canine","volume":"23","author":"Slocum","year":"1993","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1053\/jvet.2002.31041","article-title":"Effect of tibial plateau leveling on stability of the canine cranial cruciate-deficient stifle 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