{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:36:42Z","timestamp":1753893402474,"version":"3.41.2"},"reference-count":31,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>A 6-year-old male neutered boxer mix canine was presented for a one-month history of dyschezia, hematochezia, and constipation. Colonoscopy and endoscopic biopsies revealed non-specific lymphoplasmacytic, eosinophilic colitis. Despite pursuing various therapies over a 3.5-month clinical course (including hypoallergenic diet, antibiotics, prokinetics, laxatives, and anti-inflammatory glucocorticoids), the patient\u2019s condition did not improve. Two and a half months after initial presentation, the patient developed circumferential proctitis with multiple draining tracts and obstipation. Humane euthanasia and postmortem examination were elected. Gross and histological findings revealed locally extensive pyogranulomatous coloproctitis with many intralesional PAS-positive, GMS-negative 30\u201340\u2009\u03bcm in diameter, hyaline, pauciseptate, irregularly branching fungal hyphae, hyphal bodies or chlamydospores and 25\u201345\u2009\u03bcm in diameter thick-walled zygospores. Fungal culture of fluid from the draining tracts was performed, and DNA sequence analysis of the ITS and partial LSU of the nuclear ribosomal RNA genes were used to identify and confirm a novel species, <jats:italic>Basidiobolus arizonensis<\/jats:italic>. <jats:italic>Basidiobolus<\/jats:italic> spp. are saprobes in the order Basidiobolales and most commonly cause granulomatous infections of the skin, respiratory tract, and gastrointestinal tract in veterinary species and humans. To the authors\u2019 knowledge, this is the first report of novel <jats:italic>Basidiobolus arizonensis<\/jats:italic> causing localized coloproctitis in a dog.<\/jats:p>","DOI":"10.3389\/fvets.2024.1427496","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T09:23:12Z","timestamp":1725960192000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case report: Localized coloproctitis caused by novel Basidiobolus arizonensis in a dog"],"prefix":"10.3389","volume":"11","author":[{"given":"Annalise","family":"Black","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcellina","family":"Wiertek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvia","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Wycislo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Rayhel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"Reid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Wiederhold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Connie","family":"Ca\u00f1ete-Gibas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,9,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e00014-18","DOI":"10.1128\/CMR.00014-18","article-title":"Human pathogenic Entomophthorales","volume":"31","author":"Vilela","year":"2018","journal-title":"Clin Microbiol Rev"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"477","DOI":"10.5248\/120.477","article-title":"Entomophthoromycota: a new phylum and reclassification for entomophthoroid fungi","volume":"120","author":"Humber","year":"2012","journal-title":"Mycotaxon-Ithaca Ny"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s13225-018-0401-0","article-title":"High-level classification of the Fungi and a tool for evolutionary ecological analyses","volume":"90","author":"Tedersoo","year":"2018","journal-title":"Fungal Divers"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.mycres.2007.03.004","article-title":"A higher-level phylogenetic classification of the Fungi","volume":"111","author":"Hibbett","year":"2007","journal-title":"Mycol Res"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"653","DOI":"10.3390\/jof7080653","article-title":"Basidiobolus omanensis sp. nov. causing angioinvasive abdominal basidiobolomycosis","volume":"7","author":"Al-Hatmi","year":"2021","journal-title":"J Fungi (Basel)"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"2091","DOI":"10.1111\/jvim.15859","article-title":"Colorectal basidiobolomycosis in a dog","volume":"34","author":"Marclay","year":"2020","journal-title":"J Vet Intern Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1111\/eve.13392","article-title":"Beyond conidiobolomycosis \u2013 the other \u2018zygomycoses\u2019","volume":"33","author":"Johnson","year":"2021","journal-title":"Equine Vet. 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