{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T18:57:00Z","timestamp":1793905020151,"version":"4.8.0"},"reference-count":64,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p><jats:italic>Atractylodes lancea<\/jats:italic>, is a herbaceous plant of the Asteraceae family which is a traditional Chinese herbal medicine. It is often used for dehumidification, antiemetics, spleen strengthening and antipyretic effects. <jats:italic>Atractylodes lancea<\/jats:italic> is rich in various bio-active substances and has many biological functions, for instance anti-inflammatory, antioxidant and antiviral effects. Therefore, it is widely used in animal production, such as relieving heat stress, protecting intestinal health and regulating immunity. In recent years, it has received widespread attention in green cultivation. This article reviews the biological functions of <jats:italic>Atractylodes lancea<\/jats:italic> and looks forward to its application prospects in animal husbandry, in order to provide a theoretical basis for <jats:italic>Atractylodes lancea<\/jats:italic> to become a new feed additive in animal production.<\/jats:p>","DOI":"10.3389\/fvets.2024.1518433","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T06:13:37Z","timestamp":1736489617000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["The biological function of Atractylodes lancea and its application in animal husbandry: a review"],"prefix":"10.3389","volume":"11","author":[{"given":"Yang","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Difei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuexi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Leng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,1,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/0378-8741(90)90044-T","article-title":"Intestinal motility enhancing effect of Atractylodes lancea rhizome","volume":"29","author":"Yamahara","year":"1990","journal-title":"J Ethnopharmacol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/S1995-7645(14)60069-9","article-title":"Therapeutic potential and pharmacological activities of Atractylodes lancea (Thunb","volume":"7","author":"Koonrungsesomboon","year":"2014","journal-title":"Asian Pac J Trop Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"115967","DOI":"10.1016\/j.jep.2022.115967","article-title":"Deep-fried Atractylodes lancea rhizome alleviates spleen deficiency diarrhea-induced short-chain fatty acid metabolic disorder in mice by remodeling the intestinal flora","volume":"303","author":"Liu","year":"2023","journal-title":"J Ethnopharmacol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"113925","DOI":"10.1016\/j.jep.2021.113925","article-title":"Atractylodes oil alleviates diarrhea-predominant irritable bowel syndrome by regulating intestinal inflammation and intestinal barrier via SCF\/c-kit and MLCK\/MLC2 pathways","volume":"272","author":"Xie","year":"2021","journal-title":"J Ethnopharmacol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1002\/ptr.5586","article-title":"Integrative medicine for relief of nausea and vomiting in the treatment of colorectal cancer using oxaliplatin-based chemotherapy: a systematic review and meta-analysis","volume":"30","author":"Chen","year":"2016","journal-title":"Phytother Res."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1007\/s12272-011-0710-2","article-title":"Taguchi approach for anti-heat stress prescription compatibility in mice spleen lymphocytes in vitro","volume":"34","author":"Zhu","year":"2011","journal-title":"Arch Pharm Res."},{"key":"B7","doi-asserted-by":"publisher","first-page":"952061","DOI":"10.3389\/fphar.2022.952061","article-title":"The chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala Koidz","volume":"13","author":"Liu","year":"2022","journal-title":"Front Pharmacol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1260208","DOI":"10.3389\/fvets.2023.1260208","article-title":"Effects of Yu-Ping-Feng polysaccharides on animal growth performance and immune function: a review","volume":"10","author":"Chu","year":"2023","journal-title":"Front Vet Sci."},{"key":"B9","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.jep.2018.08.023","article-title":"The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz: a review","volume":"226","author":"Zhu","year":"2018","journal-title":"J Ethnopharmacol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1691\/ph.2020.9738","article-title":"Rhizoma Atractylodis macrocephalae: a review of photochemistry, pharmacokinetics and pharmacology","volume":"75","author":"Ruqiao","year":"2020","journal-title":"Pharmazie."},{"key":"B11","doi-asserted-by":"publisher","first-page":"166","DOI":"10.3390\/molecules23010166","article-title":"GC-MS analysis of the volatile constituents in the leaves of 14 compositae plants","volume":"23","author":"Wang","year":"2018","journal-title":"Molecules."},{"key":"B12","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1007\/s11418-015-0934-4","article-title":"What caused the changes in the usage of Atractylodis macrocephalae Rhizoma from ancient to current times?","volume":"70","author":"Wang","year":"2016","journal-title":"J Nat Med."},{"key":"B13","doi-asserted-by":"publisher","first-page":"863","DOI":"10.3390\/nu10070863","article-title":"Kahweol ameliorates the liver inflammation through the inhibition of NF-\u03baB and STAT3 activation in primary Kupffer cells and primary hepatocytes","volume":"10","author":"Seo","year":"2018","journal-title":"Nutrients."},{"key":"B14","doi-asserted-by":"publisher","first-page":"103725","DOI":"10.1016\/j.etap.2021.103725","article-title":"Toxic effects of hexavalent chromium (Cr6+) on bioaccumulation, apoptosis, oxidative damage and inflammatory response in Channa asiatica","volume":"87","author":"Yu","year":"2021","journal-title":"Environ Toxicol Pharmacol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/j.ijbiomac.2021.12.117","article-title":"Polysaccharide from dandelion enriched nutritional composition, antioxidant capacity, and inhibited bioaccumulation and inflammation in Channa asiatica under hexavalent chromium exposure","volume":"201","author":"Zhao","year":"2022","journal-title":"Int J Biol Macromol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1002\/ptr.2040","article-title":"Atractylenolide I and atractylenolide III inhibit Lipopolysaccharide-induced TNF-\u03b1 and NO production in macrophages","volume":"21","author":"Li","year":"2007","journal-title":"Phytother Res."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.3390\/molecules24101859","article-title":"Anti-inflammatory compounds from Atractylodes macrocephala","volume":"24","author":"Jeong","year":"2019","journal-title":"Molecules"},{"key":"B18","doi-asserted-by":"publisher","first-page":"25","DOI":"10.6116\/kjh.2016.31.5.25","article-title":"Polyacetylenic compounds from Atractylodes rhizomes","volume":"31","author":"Kim","year":"2016","journal-title":"Korea J Herbol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1146\/annurev.arplant.55.031903.141701","article-title":"Reactive oxygen species: metabolism, oxidative stress, and signal transduction","volume":"55","author":"Apel","year":"2004","journal-title":"Annu Rev Plant Biol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"13457","DOI":"10.3390\/molecules171113457","article-title":"Antioxidant ability and mechanism of rhizoma Atractylodes macrocephala","volume":"17","author":"Li","year":"2012","journal-title":"Molecules"},{"key":"B21","doi-asserted-by":"publisher","first-page":"188","DOI":"10.3390\/toxins9060188","article-title":"Embryotoxicity caused by DON-induced oxidative stress mediated by Nrf2\/HO-1 pathway","volume":"9","author":"Yu","year":"2017","journal-title":"Toxins."},{"key":"B22","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.ijbiomac.2016.01.086","article-title":"Protective effect of a polysaccharide from Rhizoma atractylodis macrocephalae on acute liver injury in mice","volume":"87","author":"Han","year":"2016","journal-title":"Int J Biol Macromol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"345","DOI":"10.5851\/kosfa.2010.30.2.345","article-title":"Screening of antiviral medicinal plants against avian influenza virus H1N1 for food safety","volume":"30","author":"Lee","year":"2010","journal-title":"Food Sci Anim Resour."},{"key":"B24","doi-asserted-by":"publisher","first-page":"68","DOI":"10.5958\/0974-360X.2016.00362.0","article-title":"Swine flu and its herbal remedies","volume":"2","author":"Shah","year":"2013","journal-title":"Int J Eng Sci."},{"key":"B25","first-page":"565","article-title":"Effective component selection of atraotydin extract against influenza virus","volume":"23","author":"Shi","year":"2012","journal-title":"Shih-chen Kuo I Kuo Yao."},{"key":"B26","doi-asserted-by":"publisher","first-page":"3704","DOI":"10.3892\/mmr.2016.5713","article-title":"Antiviral activities of atractylon from Atractylodis rhizoma","volume":"14","author":"Cheng","year":"2016","journal-title":"Mol Med Rep"},{"key":"B27","doi-asserted-by":"publisher","first-page":"727154","DOI":"10.3389\/fphar.2021.727154","article-title":"A review of the ethnopharmacology, phytochemistry, pharmacology, application, quality control, processing, toxicology, and pharmacokinetics of the dried rhizome of Atractylodes macrocephala","volume":"12","author":"Yang","year":"2021","journal-title":"Front Pharmacol"},{"key":"B28","doi-asserted-by":"publisher","first-page":"2338533","DOI":"10.1155\/2022\/2338533","article-title":"Polysaccharides from Rhizoma atractylodis macrocephalae: a review on their extraction, purification, structure, and bioactivities","volume":"2022","author":"Luo","year":"2022","journal-title":"Evid Bas Complement Alternat Med."},{"key":"B29","doi-asserted-by":"publisher","first-page":"737522","DOI":"10.1016\/j.aquaculture.2021.737522","article-title":"Dietary Taraxacum mongolicum polysaccharide ameliorates the growth, immune response, and antioxidant status in association with NF-\u03baB, Nrf2 and TOR in Jian carp (Cyprinus carpio var","volume":"547","author":"Yu","year":"2022"},{"key":"B30","doi-asserted-by":"publisher","first-page":"8391","DOI":"10.1038\/srep08391","article-title":"Fermented Rhizoma atractylodis macrocephalae alleviates high fat diet-induced obesity in association with regulation of intestinal permeability and microbiota in rats","volume":"5","author":"Wang","year":"2015","journal-title":"Sci Rep."},{"key":"B31","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1017\/S002185960999013X","article-title":"The effect of dietary addition of a polysaccharide from Atractylodes macrophala Koidz on growth performance, immunoglobulin concentration and IL-1\u03b2 expression in weaned piglets","volume":"147","author":"Li","year":"2009","journal-title":"J Agric Sci."},{"key":"B32","doi-asserted-by":"publisher","first-page":"70394","DOI":"10.18632\/oncotarget.19709","article-title":"The protective effects of polysaccharide of Atractylodes macrocephala Koidz (PAMK) on the chicken spleen under heat stress via antagonizing apoptosis and restoring the immune function","volume":"8","author":"Xu","year":"2017","journal-title":"Oncotarget."},{"key":"B33","doi-asserted-by":"publisher","first-page":"302","DOI":"10.22358\/jafs\/66078\/2012","article-title":"The effects of supplementing diets with Atractylodes macrocephala Koidz rhizomes on growth performance and immune function in piglets","volume":"21","author":"Xu","year":"2012","journal-title":"J Anim Feed Sci"},{"key":"B34","doi-asserted-by":"publisher","first-page":"103171","DOI":"10.1016\/j.psj.2023.103171","article-title":"Immunomodulatory effect of Atractylodis macrocephala Koidz. polysaccharides in vitro","volume":"103","author":"Hu","year":"2024","journal-title":"Poult Sci."},{"key":"B35","doi-asserted-by":"publisher","first-page":"2373","DOI":"10.5555\/20143326627","article-title":"Effects of Rhizoma atractylodis oil on rumen fermentation and nutrient degradability in vitro in Jinjiang yellow cattle","volume":"26","author":"Xu ZhenSong","year":"2014","journal-title":"Chin J Anim Nutri"},{"key":"B36","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.livsci.2011.06.013","article-title":"Dietary supplementation with Atractylodes macrophala Koidz polysaccharides ameliorate metabolic status and improve immune function in early-weaned pigs","volume":"142","author":"Li","year":"2011","journal-title":"Livest Sci."},{"key":"B37","doi-asserted-by":"publisher","first-page":"937745","DOI":"10.3389\/fvets.2022.937745","article-title":"The beneficial effects of traditional Chinese medicine on antioxidative status and inflammatory cytokines expression in the liver of piglets","volume":"9","author":"Wang","year":"2022","journal-title":"Front Vet Sci."},{"key":"B38","doi-asserted-by":"publisher","first-page":"932","DOI":"10.3390\/molecules23040932","article-title":"Polysaccharide of Atractylodes macrocephala Koidz (PAMK) relieves immunosuppression in cyclophosphamide-treated geese by maintaining a humoral and cellular immune balance","volume":"23","author":"Li","year":"2018","journal-title":"Molecules."},{"key":"B39","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1016\/j.carbpol.2017.07.041","article-title":"Structural analysis and immunomodulatory effect of polysaccharide from Atractylodis macrocephalae Koidz on Bovine lymphocytes","volume":"174","author":"Xu","year":"2017","journal-title":"Carbohydr Polym"},{"key":"B40","doi-asserted-by":"publisher","first-page":"363076","DOI":"10.1155\/2013\/363076","article-title":"Evaluation of in vitro anti-inflammatory activities and protective effect of fermented preparations of Rhizoma Atractylodis Macrocephalae on intestinal barrier function against lipopolysaccharide insult","volume":"2013","author":"Bose","year":"2013","journal-title":"Evid Bas Complement Alternat Med."},{"key":"B41","doi-asserted-by":"publisher","first-page":"124","DOI":"10.3390\/ijms21010124","article-title":"Deep-fried atractylodis rhizoma protects against spleen deficiency-induced diarrhea through regulating intestinal inflammatory response and gut microbiota","volume":"21","author":"Shi","year":"2019","journal-title":"Int J Mol Sci."},{"key":"B42","doi-asserted-by":"publisher","first-page":"9721353","DOI":"10.1155\/2021\/9721353","article-title":"PAMK Relieves LPS-induced enteritis and improves intestinal flora disorder in goslings","volume":"2021","author":"Li","year":"2021","journal-title":"Evid Bas Complement Alternat Med."},{"key":"B43","doi-asserted-by":"publisher","first-page":"926381","DOI":"10.1155\/2014\/926381","article-title":"The metabolism of polysaccharide from Atractylodes macrocephala Koidz and its effect on intestinal microflora","volume":"2014","author":"Wang","year":"2014","journal-title":"Evid Bas Complement Alternat Med."},{"key":"B44","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.aninu.2018.09.004","article-title":"Effect of traditional Chinese medicine compounds on rumen fermentation, methanogenesis and microbial flora in vitro","volume":"5","author":"Wang","year":"2019","journal-title":"Anim Nutr."},{"key":"B45","doi-asserted-by":"publisher","first-page":"115906","DOI":"10.1016\/j.carbpol.2020.115906","article-title":"Receptor and signaling pathway involved in bovine lymphocyte activation by Atractylodis macrocephalae polysaccharides","volume":"234","author":"Xu","year":"2020","journal-title":"Carbohydr Polym."},{"key":"B46","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1080\/01652176.2012.675091","article-title":"Demonstration of non-specific colitis and increased crypt depth in colon of weaned pigs with diarrhea","volume":"32","author":"Pedersen","year":"2012","journal-title":"Vet Quart."},{"key":"B47","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.ijbiomac.2021.12.042","article-title":"Protective effects of polysaccharides from Atractylodes macrocephalae Koidz against dextran sulfate sodium induced intestinal mucosal injury on mice","volume":"195","author":"Kai","year":"2022","journal-title":"Int J Biol Macromol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"116597","DOI":"10.1016\/j.jep.2023.116597","article-title":"The combination of Alisma and Atractylodes ameliorates cerebral ischaemia\/reperfusion injury by negatively regulating astrocyte-derived exosomal miR-200a-3p\/141-3p by targeting SIRT1","volume":"313","author":"Wei","year":"2023","journal-title":"J Ethnopharmacol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"1021695","DOI":"10.3389\/fimmu.2022.1021695","article-title":"Polysaccharide from Atractylodes macrocephala Koidz. ameliorates DSS-induced colitis in mice by regulating the Th17\/Treg cell balance","volume":"13","author":"Yang","year":"2022","journal-title":"Front Immunol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"e25355","DOI":"10.1097\/MD.0000000000025355","article-title":"Efficacy and safety of Shenling Atractylodes Powder in the treatment of ulcerative colitis: a protocol for systematic review and meta-analysis","volume":"100","author":"Zhang","year":"2021","journal-title":"Medicine."},{"key":"B51","doi-asserted-by":"publisher","first-page":"153945","DOI":"10.1016\/j.phymed.2022.153945","article-title":"Atractylenolide-1 targets SPHK1 and B4GALT2 to regulate intestinal metabolism and flora composition to improve inflammation in mice with colitis","volume":"98","author":"Qu","year":"2022","journal-title":"Phytomedicine."},{"key":"B52","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.rvsc.2019.08.011","article-title":"The impact of heat stress on the immune system in dairy cattle: a review","volume":"126","author":"Bagath","year":"2019","journal-title":"Res Vet Sci."},{"key":"B53","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/s00484-020-02023-7","article-title":"Heat stress and poultry production: impact and amelioration","volume":"65","author":"Vandana","year":"2021","journal-title":"Int J Biometeorol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"103019","DOI":"10.1016\/j.jtherbio.2021.103019","article-title":"Effect of heat stress on growth and production performance of livestock and poultry: mechanism to prevention","volume":"99","author":"Chen","year":"2021","journal-title":"J Therm Biol."},{"key":"B55","doi-asserted-by":"publisher","first-page":"3107","DOI":"10.2527\/jas.2010-3831","article-title":"Active components of common traditional Chinese medicine decoctions have antioxidant functions","volume":"89","author":"Guo","year":"2011","journal-title":"J Anim Sci."},{"key":"B56","doi-asserted-by":"publisher","first-page":"skac387","DOI":"10.1093\/jas\/skac387","article-title":"Effects of lowering dietary protein content without or with increased protein-bound and feed-grade amino acids supply on growth performance, body composition, metabolism, and acute-phase protein of finishing pigs under daily cyclic heat stress","volume":"101","author":"Jos\u00e9 Karpeggiane de Oliveira","year":"2023","journal-title":"J Anim Sci."},{"key":"B57","doi-asserted-by":"publisher","first-page":"7519","DOI":"10.1039\/C6RA27730F","article-title":"The effect of selenium and polysaccharide of Atractylodes macrocephala koidz","volume":"7","author":"Xu","year":"2017","journal-title":"RSC Adv."},{"key":"B58","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.fitote.2011.10.015","article-title":"A new 9-nor-atractylodin from Atractylodes lancea and the antibacterial activity of the atractylodin derivatives","volume":"83","author":"Chen","year":"2012","journal-title":"Fitoterapia."},{"key":"B59","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1007\/s00044-010-9311-8","article-title":"Comparative research of chemical constituents and bioactivities between petroleum ether extracts of the aerial part and the rhizome of Atractylodes macrocephala","volume":"20","author":"Peng","year":"2011","journal-title":"Med Chem Res"},{"key":"B60","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.neulet.2018.06.057","volume":"684","author":"Ohara","year":"2018","journal-title":"Neurosci Lett."},{"key":"B61","doi-asserted-by":"publisher","first-page":"451","DOI":"10.3390\/nu9050451","article-title":"Neuroprotective role of atractylenolide-I in an in vitro and in vivo model of Parkinson's disease","volume":"9","author":"More","year":"2017","journal-title":"Nutrients."},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.113415","author":"Zhang","year":"","journal-title":"J Ethnopharmacol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"4015","DOI":"10.3390\/ijms20164015","article-title":"Atractylodis rhizoma alba attenuates neuroinflammation in BV2 microglia upon LPS stimulation by inducing HO-1 activity and inhibiting NF-\u03baB and MAPK","volume":"20","author":"Jeong","year":"2019","journal-title":"Int J Mol Sci."},{"key":"B64","doi-asserted-by":"publisher","first-page":"103332","DOI":"10.1016\/j.jtherbio.2022.103332","article-title":"Biomarkers of heat stress and mechanism of heat stress response in Avian species: current insights and future perspectives from poultry science","volume":"110","author":"Oladokun","year":"2022","journal-title":"J Therm Biol."}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2024.1518433\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T06:13:41Z","timestamp":1736489621000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2024.1518433\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,10]]},"references-count":64,"alternative-id":["10.3389\/fvets.2024.1518433"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2024.1518433","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,10]]},"article-number":"1518433"}}