{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:15:16Z","timestamp":1792523716623,"version":"4.5.0"},"reference-count":42,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>A 10-month-old intact female Cane Corso dog was referred to the Veterinary Teaching Hospital of the University of Perugia (PG-VTH) for severe hemolytic anemia and thrombocytopenia. The dog had never traveled abroad and was regularly treated with antiparasitic products. On physical examination, the dog showed lethargy, delayed growth, weight loss, pale mucous membranes, and abdominal pain. The temperature was normal, and on examination, no ectoparasites were observed on the animal\u2019s body surface. The main laboratory findings were hemolytic anemia, thrombocytopenia, and elevated liver enzymes. <jats:italic>Babesia<\/jats:italic> infection was initially diagnosed by blood smear evaluation via May\u2013Gr\u00fcnwald\u2013Giemsa staining and then confirmed by real-time polymerase chain reaction analysis; further sequencing analysis attributed the infection to <jats:italic>Babesia vulpes<\/jats:italic> (<jats:italic>B. vulpes<\/jats:italic>). An initial treatment with imidocarb dipropionate was only partially effective, while resolution of the infection was reached afterward with a combination of Malarone<jats:sup>\u00ae<\/jats:sup> and azithromycin therapy. To the authors\u2019 knowledge, this report describes the first case of <jats:italic>B. vulpes<\/jats:italic> infection in a dog in Italy.<\/jats:p>","DOI":"10.3389\/fvets.2025.1498721","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T11:42:06Z","timestamp":1739965326000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Case report: First autochthonous Babesia vulpes infection in a dog from Italy"],"prefix":"10.3389","volume":"12","author":[{"given":"Maria Teresa","family":"Antognoni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Cremonini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambra Lisa","family":"Misia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Gobbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Toniolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Miglio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,2,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.vetpar.2015.04.020","article-title":"The role of wild canids and felids in spreading parasites to dogs and cats in Europe. 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