{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:06:05Z","timestamp":1791547565509,"version":"4.3.4"},"reference-count":44,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>Kidney diseases are observed in various wild animal species, more often noted in captive than in free-ranging animals. There are few reports in roe deer (<jats:italic>Capreolus capreolus<\/jats:italic>). Two kidney malformations were encountered while reviewing and collecting the roe deer samples. Kidney malformations were found in samples from two roe deer in Central Poland, one in 5-year-old female near W\u0119gr\u00f3w (50\u202fkm northeast of Warsaw) and one in 7-year-old male near Rawa Mazowiecka (75\u202fkm southwest of Warsaw). The female had a smaller (5\u202fcm long and weighed 20\u202fg) shrunken kidney (no prominent histopathological changes) and compensatory hypertrophy of the other kidney (weighting 85.8\u202fg). A diagnosis of renal hypoplasia was made. The male had a smaller kidney (4.5\u202fcm long and weighed 15.3\u202fg) and normal-sized the other kidney (7.5\u202fcm and 55.6\u202fg). Massive mononuclear infiltrates composed mainly of lymphocytes and plasma cells in the renal interstitium, with hyperplasia of the connective tissue and multifocal glomerular sclerosis, were found in both kidneys. Diagnosis of chronic interstitial nephritis was made.<\/jats:p>","DOI":"10.3389\/fvets.2025.1523216","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T06:52:24Z","timestamp":1739861544000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case report: Renal malformations in wild roe deer (Capreolus capreolus) in Central Poland"],"prefix":"10.3389","volume":"12","author":[{"given":"Katarzyna","family":"Kliczkowska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Bielecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Kloch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"\u015awi\u0105tek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Klich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1638\/2013-0071R.1","article-title":"A retrospective study of end-stage renal disease in captive polar bears (Ursus maritimus)","volume":"45","author":"LaDouceur","year":"2014","journal-title":"J Zoo Wildl Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1638\/2013-0137R2.1","article-title":"Chronic renal disease in a captive two-toed sloth (Choloepus didactylus) with concurrent hepatocellular carcinoma","volume":"45","author":"Salas","year":"2014","journal-title":"J Zoo Wildl Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4102\/ojvr.v84i1.1210","article-title":"Prevalence and renal pathology of pathogenic Leptospira spp. in wildlife in Abeokuta, Ogun State, Nigeria","volume":"84","author":"Ajayi","year":"2017","journal-title":"Onderstepoort J Vet Res"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"620685","DOI":"10.3389\/fvets.2020.620685","article-title":"Health and disease in free-ranging and captive wildlife","volume":"7","author":"Ossiboff","year":"2020","journal-title":"Front Vet Sci"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1166\/jnef.2013.1047","article-title":"Initial examination of wild large game on the spot\u2014importance and rules","volume":"1","author":"Vieira-Pinto","year":"2013","journal-title":"J Nutr Ecol Food Res"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1638\/2012-0131R.1","article-title":"Polycystic kidney disease in a European roe deer (Capreolus capreolus)","volume":"44","author":"Blutke","year":"2013","journal-title":"J Zoo Wildl Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e0170338","DOI":"10.1371\/journal.pone.0170338","article-title":"Assessing fifty years of general health surveillance of roe deer in Switzerland: a retrospective analysis of necropsy reports","volume":"12","author":"Pewsner","year":"2017","journal-title":"PLoS One"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1177\/104063870401600522","article-title":"Congenital polycystic kidney in a white-tailed deer (Odocoileus virginianus)","volume":"16","author":"Palmer","year":"2004","journal-title":"J Vet Diagn Invest"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"285","DOI":"10.12834\/VetIt.1309.06","article-title":"Leptospira spp. infection in wild ruminants: a survey in central Italian Alps","volume":"50","author":"Andreoli","year":"2014","journal-title":"Vet Ital"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1002\/etc.5620210908","article-title":"Environmental cadmium induces histopathological changes in kidneys of roe deer","volume":"21","author":"Beiglb\u00f6ck","year":"2002","journal-title":"Environ Toxicol Chem"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1007\/978-4-431-77134-0_10","article-title":"Wildlife disease surveillance and monitoring","author":"Artois","year":"2009"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1186\/1746-6148-9-223","article-title":"Wildlife health investigations: needs, challenges and recommendations","volume":"9","author":"Ryser-Degiorgis","year":"2013","journal-title":"BMC Vet Res"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1080\/21658005.2018.1537905","article-title":"Frequency of abnormalities in wildlife species: is there a relation with their ecology?","volume":"28","author":"Sokos","year":"2018","journal-title":"Zool Ecol"},{"key":"ref14","article-title":"Ordinance of the minister of agriculture and rural development of July 4, 2017 on the method of keeping documentation related to combating infectious animal diseases (NS. Of Laws of 2017, item 1388)","year":""},{"key":"ref15","volume-title":"Jubb, Kennedy, and Palmer\u2019s pathology of domestic animals","author":"Maxie","year":"2016"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1093\/ckj\/sfs186","article-title":"Congenital anomalies of kidney and hand: a review","volume":"6","author":"Natarajan","year":"2013","journal-title":"Clin Kidney J"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"106658","DOI":"10.1016\/j.ecolind.2020.106658","article-title":"Roe deer stress response to a wind farms: methodological and practical implications","volume":"117","author":"Klich","year":"2020","journal-title":"Ecol Indic"},{"key":"ref18","first-page":"1","article-title":"The impacts of wind power on terrestrial mammals: a synthesis","author":"Helldin","year":"2012","journal-title":"SEPA Naturv\u00e5rdsverket"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"9906","DOI":"10.1002\/ece3.4476","article-title":"Out of sight of wind turbines\u2014reindeer response to wind farms in operation","volume":"8","author":"Skarin","year":"2018","journal-title":"Ecol Evol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"65","DOI":"10.4103\/ed.ed_16_21","article-title":"Wind turbines and adverse health effects: applying Bradford Hill's criteria for causation","volume":"6","author":"Dumbrille","year":"2021","journal-title":"Environ Dis"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"e108","DOI":"10.1097\/JOM.0000000000000313","article-title":"Wind turbines and health: a critical review of the scientific literature","volume":"56","author":"McCunney","year":"2014","journal-title":"J Occup Environ Med"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.applanim.2017.05.023","article-title":"Reindeer spatial use before, during and after construction of a wind farm","volume":"195","author":"Tsegaye","year":"2017","journal-title":"Appl Anim Behav Sci"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"e02692","DOI":"10.1016\/j.gecco.2023.e02692","article-title":"Occupancy model to unveil wildlife utilization at Yeongyang-gun wind farm management road, Korea","volume":"48","author":"Kim","year":"2023","journal-title":"Glob Ecol Conserv"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1038\/s41598-022-05159-1","article-title":"Responses of birds and mammals to long-established wind farms in India","volume":"12","author":"Kumara","year":"2022","journal-title":"Sci Rep"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"25290","DOI":"10.1038\/s41598-024-76999-2","article-title":"The contingent impact of wind farms on game mammal density demonstrated in a large-scale analysis of hunting bag data in Poland","volume":"14","author":"Klich","year":"2024","journal-title":"Sci Rep"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.ecolind.2017.08.052","article-title":"Living in habitats affected by wind turbines may result in an increase in corticosterone levels in ground dwelling animals","volume":"84","author":"\u0141opucki","year":"2018","journal-title":"Ecol Indic"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1515\/aoas-2015-0051","article-title":"The effect of varying distances from the wind turbine on meat quality of growing-finishing pigs","volume":"15","author":"Karwowska","year":"2015","journal-title":"Ann Anim Sci"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"679","DOI":"10.2478\/pjvs-2013-0096","article-title":"Preliminary studies on the reaction of growing geese (Anser anser f. domestica) to the proximity of wind turbines","volume":"16","author":"Mikolajczak","year":"2013","journal-title":"Pol J Vet Sci"},{"key":"ref29","volume-title":"Robbins basic pathology","author":"Kumar","year":"2017"},{"key":"ref30","year":"2023"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1007\/s10646-010-0488-x","article-title":"Cadmium accumulation, metallothionein and glutathione levels, and histopathological changes in the kidneys and liver of magpie (Pica pica) from a zinc smelter area","volume":"19","author":"W\u0142ostowski","year":"2010","journal-title":"Ecotoxicology"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1016\/j.etap.2014.02.013","article-title":"Betaine supplementation protects against renal injury induced by cadmium intoxication in rats: role of oxidative stress and caspase-3","volume":"37","author":"Hagar","year":"2014","journal-title":"Environ Toxicol Pharmacol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.taap.2009.04.020","article-title":"Current status of cadmium as an environmental health problem","volume":"238","author":"J\u00e4rup","year":"2009","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref34","first-page":"739","article-title":"Progress in research on biomarkers of cadmium induced renal toxicity","volume":"28","author":"Wu","year":"2011","journal-title":"J Environ Health"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/j.aquatox.2009.07.014","article-title":"Effect of cadmium in the clam Ruditapes decussatus assessed by proteomic analysis","volume":"94","author":"Chora","year":"2009","journal-title":"Aquat Toxicol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"8478","DOI":"10.1021\/es9006405","article-title":"Importance of considering the framework principles in risk assessment for metals","volume":"43","author":"Menzie","year":"2009","journal-title":"Environ Sci Technol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"3710","DOI":"10.1021\/es1037222","article-title":"Metabolomics of microliter hemolymph samples enables an improved understanding of the combined metabolic and transcriptional responses of Daphnia magna to cadmium","volume":"45","author":"Poynton","year":"2011","journal-title":"Environ Sci Technol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"305","DOI":"10.3390\/ani14020305","article-title":"Cadmium in selected organs of game animals from areas with different degrees of industrialisation and its intake by human consumers","volume":"14","author":"B\u0105kowska","year":"2024","journal-title":"Animals"},{"key":"ref39","first-page":"205","article-title":"Bioaccumulation of lead, cadmium and mercury in roe deer and wild boars from areas with different levels of toxic metal pollution","volume":"9","author":"Durkalec","year":"2015","journal-title":"Int J Environ Res"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.3390\/ani10091519","article-title":"Content of selected macro-and microelements in the liver of free-living wild boars (Sus scrofa L.) from agricultural areas and health risks associated with consumption of liver","volume":"10","author":"Kasprzyk","year":"2020","journal-title":"Animals"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"143926","DOI":"10.1016\/j.scitotenv.2020.143926","article-title":"Essential differences in the mineral status of free-ranging European bison Bison bonasus populations in Poland: the effect of the anthroposphere and lithosphere","volume":"757","author":"Klich","year":"2021","journal-title":"Sci Total Environ"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"p107","DOI":"10.1159\/000095539","article-title":"Common mechanisms in nephropathy induced by toxic metals","volume":"104","author":"Saboli\u0107","year":"2006","journal-title":"Nephron Physiol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2019\/6730305","article-title":"Environmental chemistry and ecotoxicology of hazardous heavy metals: environmental persistence, toxicity, and bioaccumulation","volume":"2019","author":"Ali","year":"2019","journal-title":"J Chem"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1007\/s10653-024-01991-8","article-title":"Heavy metal and metalloid concentrations in red deer (Cervus elaphus) and their human health implications from one health perspective","volume":"46","author":"Jota Baptista","year":"2024","journal-title":"Environ Geochem Health"}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2025.1523216\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T06:52:28Z","timestamp":1739861548000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2025.1523216\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,18]]},"references-count":44,"alternative-id":["10.3389\/fvets.2025.1523216"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2025.1523216","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,18]]},"article-number":"1523216"}}