{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:10:08Z","timestamp":1758813008956,"version":"3.44.0"},"reference-count":42,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>Oviduct represents the original place of fertilisation and early embryo development in all the domestic animals. In past time it has been considered a mere channel but new reproductive biotechnology approaches suggested the need of structurally and functionally efficient oviductal environment for <jats:italic>in vitro<\/jats:italic> embryo production. Recreating the oviductal microenvironment in IVP systems represents a paradigm shift in reproductive biotechnology. By incorporating reproductive fluids and utilising advanced 3D culture models could be reduced adverse IVP outcomes, and bring assisted reproduction closer to its natural counterpart.<\/jats:p>","DOI":"10.3389\/fvets.2025.1617740","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T14:52:55Z","timestamp":1758811975000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Nature does it better: mimicking in vivo conditions to resolve in vitro production side effects"],"prefix":"10.3389","volume":"12","author":[{"given":"Enrico","family":"Dalle Palle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koray","family":"Tekin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Calogero","family":"Stelletta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1530\/REP-12-0279","article-title":"Roles of the oviduct in mammalian fertilization","volume":"144","author":"Coy","year":"2012","journal-title":"Reproduction"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"522","DOI":"10.4103\/1008-682X.153544","article-title":"Odyssey of the spermatozoon","volume":"17","author":"Varner","year":"2015","journal-title":"Asian J 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