{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:17:55Z","timestamp":1755224275874,"version":"3.43.0"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>Gastric plasmacytoma is rare in dogs, with only four previous reports providing limited descriptions of abdominal ultrasound (AUS) and computed tomography (CT) findings. This study presents the AUS and CT imaging features of two histopathologically suspected gastric plasmacytomas. Combining the four previous and two new cases, these tumors predominantly occurred in the greater curvature and pyloric antrum as solitary round masses connected to the submucosal or transmural layers. Pre- and post-contrast tissue attenuation (Hounsfield unit; HU) differences exceeded 40, with variable AUS echogenicity and echotexture. Imaging features may resemble those of spindle cell tumors, requiring histological and immunohistochemical examinations for definitive diagnosis.<\/jats:p>","DOI":"10.3389\/fvets.2025.1634049","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T12:39:31Z","timestamp":1755002371000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Ultrasonographic and computed tomographic features of presumed gastric plasmacytoma (plasma cell tumor) with ulceration in two dogs"],"prefix":"10.3389","volume":"12","author":[{"given":"Seoro","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soyoung","family":"Jeung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yewon","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matti","family":"Kiupel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kichang","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakyoung","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"190","DOI":"10.15312\/EurasianJVetSci.2023.417","article-title":"A case of plasmacytoma with widespread metastasis in a dog","volume":"39","author":"Dagar","year":"2023","journal-title":"Eurasian J Vet Sci"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jcpa.2015.10.181","article-title":"Canine gastric pathology: a review","volume":"154","author":"Amorim","year":"2016","journal-title":"J Comp Pathol"},{"key":"ref3","first-page":"415","article-title":"Canine gastric adenocarcinoma","volume":"29","author":"Gualtieri","year":"1999","journal-title":"Vet Clin N Am: Small Anim Pract"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.2460\/javma.1992.200.10.1501","article-title":"Gastric extramedullary plasmacytoma in a dog","volume":"200","author":"Brunnert","year":"1992","journal-title":"J Am Vet Med Assoc"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/S0195-5616(99)50029-6","article-title":"Gastric neoplasia","volume":"29","author":"Gualtieri","year":"1999","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1111\/vcp.12503","article-title":"A metastatic secretory gastric plasmacytoma with aberrant CD 3 expression in a dog","volume":"46","author":"Atherton","year":"2017","journal-title":"Vet Clin Pathol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.jcpa.2021.06.005","article-title":"Gastric Plasmacytoma with immunoglobulin lambda light chain deposition in a dog","volume":"187","author":"Hanari","year":"2021","journal-title":"J Comp Pathol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/j.gie.2014.02.1025","article-title":"Extraosseous plasmacytoma of the stomach","volume":"80","author":"Parikh","year":"2014","journal-title":"Gastrointest Endosc"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"134","DOI":"10.3390\/medicina58010134","article-title":"Duodenal ulcer with massive gastrointestinal hemorrhage as an initial manifestation in multiple myeloma with extramedullary disease: a case report","volume":"58","author":"Chiu","year":"2022","journal-title":"Medicina"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"e01040","DOI":"10.14309\/crj.0000000000001040","article-title":"Not your everyday duodenal ulcer: massive gastrointestinal bleed secondary to extramedullary plasma cell myeloma","volume":"10","author":"Fiske","year":"2023","journal-title":"ACG Case Rep J"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"309","DOI":"10.3816\/CLM.2008.n.044","article-title":"Gastrointestinal plasmacytoma presenting as gastrointestinal bleeding","volume":"8","author":"Suvannasankha","year":"2008","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1024\/0036-7281\/a000652","article-title":"Diagnostic imaging and endoscopic finding in dogs and cats with gastric tumors: a review","volume":"156","author":"Terragni","year":"2014","journal-title":"Schweiz Arch Tierheilkd"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1111\/vru.12980","article-title":"Comparison of the clinical, ultrasound, and CT findings in 13 dogs with gastric neoplasia","volume":"62","author":"Zuercher","year":"2021","journal-title":"Vet Radiol Ultrasound"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1111\/vru.13188","article-title":"CT features of gastrointestinal spindle cell, epithelial, and round cell tumors in 41 dogs","volume":"64","author":"De Magistris","year":"2023","journal-title":"Vet Radiol Ultrasound"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/B978-0-323-59496-7.00023-2","article-title":"Tumors of the gastrointestinal tract","volume-title":"Withrow and MacEwen\u2019s small animal clinical oncology","author":"Vail","year":"2020"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1111\/vru.12677","article-title":"Contrast-enhanced computed tomography may be helpful for characterizing and staging canine gastric tumors","volume":"60","author":"Tanaka","year":"2019","journal-title":"Vet Radiol Ultrasound"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1111\/j.1754-9485.2011.02329.x","article-title":"CT features of peripheral T-cell lymphoma in the gastrointestinal tract in Chinese population and literature review","volume":"56","author":"Zhu","year":"2012","journal-title":"J Med Imaging Radiat Oncol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"2025","DOI":"10.1002\/1097-0142(19820515)49:10<2025::AID-CNCR2820491014>3.0.CO;2-X","article-title":"Gastric plasmacytoma: An immunologic and immunohistochemical study","volume":"49","author":"Nakanishi","year":"1982","journal-title":"Cancer"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1309\/5EL22BH45PHUPM8P","article-title":"Immunophenotypic differentiation between neoplastic plasma cells in mature B-cell lymphoma vs plasma cell myeloma","volume":"127","author":"Seegmiller","year":"2007","journal-title":"Am J Clin Pathol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1177\/1040638720938687","article-title":"Chromogenic in situ hybridization for the detection of lambda and kappa immunoglobulin light chains as a potential auxiliary diagnostic technique in canine plasmacytomas","volume":"32","author":"Foiani","year":"2020","journal-title":"J Vet Diagn Invest"},{"key":"ref21","first-page":"519","article-title":"Gastric plasmacytoma: case report","volume":"31","author":"Brock","year":"1965","journal-title":"Am Surg"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1354\/vp.08-VP-0266-R-CR","article-title":"Rectal plasmacytoma with intracellular hemosiderin in a dog","volume":"46","author":"Rannou","year":"2009","journal-title":"Vet Pathol"}],"container-title":["Frontiers in Veterinary Science"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2025.1634049\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T12:39:33Z","timestamp":1755002373000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fvets.2025.1634049\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,12]]},"references-count":22,"alternative-id":["10.3389\/fvets.2025.1634049"],"URL":"https:\/\/doi.org\/10.3389\/fvets.2025.1634049","relation":{},"ISSN":["2297-1769"],"issn-type":[{"value":"2297-1769","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,12]]},"article-number":"1634049"}}