{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T15:15:54Z","timestamp":1766070954301,"version":"3.48.0"},"reference-count":99,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>\n                    The study\u2019s objective was to isolate\n                    <jats:italic>Staphylococcus pseudintermedius<\/jats:italic>\n                    from dogs with superficial pyoderma and\/or recurrent otitis, and their guardians, to determine oxacillin, cefovecin, and gentamicin resistance, associated risk factors for infection, and genetic similarity between isolates from dogs and guardians. Prevalence of\n                    <jats:italic>S. pseudintermedius<\/jats:italic>\n                    in dogs was 76% and in humans was 56%, with concurrent identification in 44%. Oxacillin resistance occurred in 6.38% of dog isolates and 11.36% of isolates from guardians, with relatively strong (disk diffusion test) or moderate (Minimum Inhibitory Concentration) association between phenotypic testing and\n                    <jats:italic>mecA<\/jats:italic>\n                    gene presence. For cefovecin, dog isolates presented resistance in 8.15% disk diffusion and 23.40% broth microdilution. In humans, 6.81 and 36.36% showed cefovecin resistance in disk diffusion and Minimum Inhibitory Concentration tests. Gentamicin resistance in dogs was identified in broth microdilution testing in 2.12%.\n                    <jats:italic>fnbB<\/jats:italic>\n                    was identified in 4.39% of isolates with relatively strong association between results of dogs and humans. Dogs sleeping with\n                    <jats:italic>S. pseudintermedius<\/jats:italic>\n                    -positive humans were 6 times more likely to test positive, and dogs attending grooming sessions were 4 times more likely positive for\n                    <jats:italic>S. pseudintermedius<\/jats:italic>\n                    . The whole genome sequencing revealed transmission between dogs and humans in 3 cases. Resistance genes for 8 antibiotic classes were found in chromosomal and plasmid genomes.\n                  <\/jats:p>","DOI":"10.3389\/fvets.2025.1652593","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T15:13:31Z","timestamp":1766070811000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Genetic connections and antimicrobial resistance in dogs and owners Staphylococcus pseudintermedius isolates"],"prefix":"10.3389","volume":"12","author":[{"given":"Christina Resende","family":"Martins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta Torres","family":"de Melo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara Mariano","family":"Bastos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafaela Oliveira","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda Gubert","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquelline","family":"Figueiredo Braz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela de Paiva","family":"Loures","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belchiolina Beatriz","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Beatriz Garcez","family":"Buiatte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Bryan","family":"Heinemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus Vinicius Can\u00e1rio","family":"Viana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1via Figueira","family":"Aburjaile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasco Ariston de Carvalho","family":"Azevedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertram","family":"Brenig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mateus Matiuzzi","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daise 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