{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:15:47Z","timestamp":1771481747872,"version":"3.50.1"},"reference-count":32,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>This report describes a canine case of severe hypocalcaemia following the surgical removal of a thyroid lobe and the ipsilateral parathyroid glands for thyroid carcinoma. After initial stabilisation with intravenous calcium gluconate, the dog was initially managed with a commercial diet, and subsequently with a homemade diet, which provided 3.72 and 3.30\u202fg\/1,000\u202fkcal ME of calcium, 376 and 295\u202fIU of vitamin D3, and 2.48 and 1.50\u202fg\/1,000\u202fkcal metabolisable energy (ME) of phosphorus, respectively. Both nutritional plans were supplemented with calcium carbonate (200\u202fmg\/day) and calcitriol (9.84\u202fIU\/day) to maintain normocalcaemia. A tailored, homemade diet was formulated to address the onset of hyporexia. The patient maintained stable serum calcium, phosphorus, and total 25(OH) vitamin D concentrations over a mid-term follow-up period of 6\u202fmonths.<\/jats:p>","DOI":"10.3389\/fvets.2026.1663570","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T05:23:05Z","timestamp":1771478585000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: long-term calcaemia management in a dog after thyroidectomy and parathyroidectomy"],"prefix":"10.3389","volume":"13","author":[{"given":"Alessio","family":"Ruggiero","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine and Animal Production, University of Napoli Federico II","place":["Naples, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camilla","family":"Sangiuliano","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Animal Production, University of Napoli Federico II","place":["Naples, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica Isabella","family":"Cutrignelli","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Animal Production, University of Napoli Federico II","place":["Naples, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Navas","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Animal Production, University of Napoli Federico II","place":["Naples, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Bergero","sequence":"additional","affiliation":[{"name":"Department of Veterinary Science of the University of Turin","place":["Grugliasco, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1111\/jsap.13401","article-title":"Vitamin D metabolism and disorders in dogs and cats","volume":"62","author":"Clarke","year":"2021","journal-title":"J Small Anim Pract"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1053\/j.tcam.2012.11.001","article-title":"Endocrine causes of calcium disorders","volume":"27","author":"Greco","year":"2012","journal-title":"Top Companion Anim Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1564","DOI":"10.1038\/s41598-020-58524-3","article-title":"Parathyroid hormone receptor 1 (PTHR1) is a prognostic indicator in canine osteosarcoma","volume":"10","author":"Al-Khan","year":"2020","journal-title":"Sci Rep"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1111\/vcp.12244","article-title":"Hypercalcemia and parathyroid hormone-related peptide expression in a dog with thyroid carcinoma and histiocytic sarcoma","volume":"44","author":"Scruggs","year":"2015","journal-title":"Vet Clin Pathol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1111\/jvim.14653","article-title":"Association of Vitamin D Metabolites with parathyroid hormone, fibroblast growth Factor-23, calcium, and phosphorus in dogs with various stages of chronic kidney disease","volume":"31","author":"Parker","year":"2017","journal-title":"J Vet Intern Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/s0039-6060(05)80064-9","article-title":"Hypercalcemia decreases bile flow and increases biliary calcium in the prairie dog","volume":"117","author":"Ahrendt","year":"1995","journal-title":"Surgery"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1016\/j.cvsm.2021.01.007","article-title":"Nutritional management for dogs and cats with chronic kidney disease","volume":"51","author":"Parker","year":"2021","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"ref8","first-page":"1101","article-title":"Paraneoplastic hypercalcemia in a dog with thyroid carcinoma","volume":"53","author":"Lane","year":"2012","journal-title":"Can Vet J"},{"key":"ref9","article-title":"Chapter 57: Calcium disorders","volume-title":"Small animal critical care medicine","author":"de Brito Galvao","year":"2022"},{"key":"ref10","article-title":"Chapter 38: canine urolithiasis: definitions, pathophysiology and clinical manifestations","volume-title":"Small animal clinical nutrition","author":"Osborne","year":"2005"},{"key":"ref11","first-page":"10","article-title":"Developmental and validation of a body condition score system for dogs","volume":"22","author":"Laflamme","year":"1997","journal-title":"Canine Pract"},{"key":"ref12","article-title":"Muscle Condition Score. 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