{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T17:04:22Z","timestamp":1779987862591,"version":"3.53.1"},"reference-count":43,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Porous tibial tuberosity advancement (porous-TTA) is a surgical technique used to treat cranial cruciate ligament (CCL) rupture in dogs. However, there is a lack of studies evaluating its application without technical modifications such as the inclusion of a flange- under real-world clinical conditions and with standardized monitoring of bone healing and osteoarthritis progression. This pilot study aims to provide preliminary clinical data on porous-TTA without a flange.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>Seventeen stifles diagnosed with CCL rupture treated with porous-TTA without a flange were included. Clinical, functional, and radiographic parameters were evaluated preoperatively, at 1 week, and 1 month postoperatively, including bone healing and osteoarthritis progression through osteophyte grading.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All patients demonstrated satisfactory clinical progress. Early bone healing was observed in all cases, and no radiographic progression of osteoarthritis was noted 1 month after surgery. Tibial crest fissures and non-displaced fractures occurred in 7\/17 (41%) and 2\/17 (12%) stifles, respectively, but none resulted in clinical signs or required additional intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Porous-TTA without the use of a flange demonstrated promising short-term functional outcomes. Despite the high incidence of tibial crest fissures and fractures, their clinical impact was minimal. These findings should be interpreted with caution due to the small sample size, absence of a control group, and short follow-up period, and should be considered preliminary and as a useful foundation for designing future long-term and controlled studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fvets.2026.1719237","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T16:34:51Z","timestamp":1779986091000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Porous tibial tuberosity advancement without using flange for the treatment of cranial cruciate ligament rupture in dogs\u2014a clinical pilot study"],"prefix":"10.3389","volume":"13","author":[{"given":"Mario","family":"Garc\u00eda-Gonz\u00e1lez","sequence":"first","affiliation":[{"name":"Anatomy, Animal Production and Veterinary Clinical Sciences Department, Veterinary Faculty, Universidade de Santiago de Compostela","place":["Lugo, Spain"]},{"name":"3B's Research Group, I3B's\u2014Research Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco","place":["Guimar\u00e3es, Portugal"]},{"name":"ICVS\/3B's\u2014PT Government Associate Laboratory","place":["Braga\/Guimar\u00e3es, Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9ctor","family":"Mart\u00ednez-Campos","sequence":"additional","affiliation":[{"name":"Hospital Veterinario Puchol, Calle de Sauceda","place":["Madrid, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Ramos-Bou","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Veterinaria MediVet San Carlos","place":["Alicante, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Gonz\u00e1lez-Cantalapiedra","sequence":"additional","affiliation":[{"name":"Anatomy, Animal Production and Veterinary Clinical Sciences Department, Veterinary Faculty, Universidade de Santiago de Compostela","place":["Lugo, Spain"]},{"name":"Rof-Codina Veterinary Teaching Hospital, Faculty of Veterinary, Universidade de Santiago de Compostela","place":["Lugo, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1111\/j.1751-0813.1995.tb03555.x","article-title":"Cranial cruciate ligament rupture in the dog\u2013a retrospective study comparing surgical techniques","volume":"72","author":"Moore","year":"1995","journal-title":"Aust Vet J."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1818","DOI":"10.2460\/javma.232.12.1818","article-title":"Prevalence of and risk factors for hip dysplasia and cranial cruciate ligament deficiency in dogs","volume":"232","author":"Witsberger","year":"2008","journal-title":"J Am Vet Med Assoc."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1004637","DOI":"10.3389\/fvets.2022.1004637","article-title":"Surgical treatment of cranial cruciate ligament disease in dogs using Tibial Plateau leveling osteotomy or tibial tuberosity advancement\u2013A systematic review with a meta-analytic approach","volume":"9","author":"Wemmers","year":"2022","journal-title":"Front Vet Sci"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.3390\/ani11051271","article-title":"Preliminary clinical and radiographic evaluation of a novel resorbable implant of polylactic acid (PLA) for tibial tuberosity advancement (TTA) by modified maquet technique (MMT)","volume":"11","author":"Vali\u00f1o-Cultelli","year":"2021","journal-title":"Animals."},{"key":"B5","doi-asserted-by":"publisher","first-page":"16","DOI":"10.3415\/VCOT-07-08-0078","article-title":"Tibial tuberosity conformation as a risk factor for cranial cruciate ligament rupture in the dog - 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