{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T16:16:06Z","timestamp":1776096966614,"version":"3.50.1"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>\n                    The study investigated placental efficiency, histomorphometry, and hormonal concentrations (progesterone, estradiol 17\u03b2, and cortisol) alongside oxidative stress indicators (malondialdehyde (MDA) and total antioxidant capacity (TAC)) and performed correlation analyses among these parameters in eutocia, dystocia, and uterine inertia deliveries in dromedary camels. A total of 24 pregnant dromedary camels, aged 8\u201311\u202fyears, with an average body weight of 520\u202f\u00b1\u202f75\u202fkg, were categorized into three groups based on parturition outcome: the eutocia group (EG),\n                    <jats:italic>n<\/jats:italic>\n                    =\u202f12; the dystocia group (DG),\n                    <jats:italic>n<\/jats:italic>\n                    =\u202f5; and the uterine inertia group (UIG).\n                    <jats:italic>n<\/jats:italic>\n                    =\u202f7. The results revealed significantly lower (\n                    <jats:italic>p<\/jats:italic>\n                    &amp;lt;\u202f0.05) syncytiotrophoblast layer thickness, chorionic villi length and diameter, and syncytiotrophoblast layer integrity in dystocia deliveries. Additionally, the inflammatory cell infiltration was higher (\n                    <jats:italic>p<\/jats:italic>\n                    &amp;lt;\u202f0.01) in DG than in UIG and EG. The placentas from EG had long, slender, and highly vascularized chorionic villi, while in DG placentas, the villi were shorter and atrophied. Progesterone concentrations were significantly higher (\n                    <jats:italic>p<\/jats:italic>\n                    &amp;lt;\u202f0.01) in DG compared to UIG and EG. While DG had the lowest mean estradiol-17\u03b2 concentration, EG had the highest. Moreover, MDA and TAC concentrations were lowest in the EG group, followed by the UIG group and then the DG group. Additionally, a positive correlation was found between chorionic villi diameter and placental efficiency, and between placental efficiency and vascular density. There were negative correlations among hormonal, antioxidant, placental efficiency, and histomorphometry parameters, as well as among these parameters and inflammatory cell infiltration. In conclusion, dystocia in camels was associated with hormonal dysregulation, presumably oxidative stress, and placental structural damage. However, for a definitive and powerful outline, further studies on large and more balanced populations are necessary in the future.\n                  <\/jats:p>","DOI":"10.3389\/fvets.2026.1750741","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T13:46:11Z","timestamp":1772459171000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["An exploratory study on the placental efficiency, histomorphometric characteristics, hormonal shifts, and oxidative stress in dromedary camels with dystocia"],"prefix":"10.3389","volume":"13","author":[{"given":"Montaser Elsayed","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Animal Productions, Faculty of Agriculture, Al-Azhar University","place":["Assiut, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ragab H.","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, Aswan University","place":["Aswan, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Veterinary Medicine, Aswan University","place":["Aswan, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amna H. M.","family":"Nour","sequence":"additional","affiliation":[{"name":"Department of Zoology, Faculty of Science, Aswan University","place":["Aswan, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan A.","family":"Hussein","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, Assiut University","place":["Assiut, Egypt"]},{"name":"Department of Surgery, Obstetrics and Artificial Insemination, Faculty of Veterinary Medicine, Sphinx University","place":["New Assiut, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Asran","family":"Elbehiry","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Veterinary Medicine, Damanhour University","place":["Damanhour, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Abdelrahman","sequence":"additional","affiliation":[{"name":"Department of Animal Production, Faculty of Agriculture, Assuit University","place":["Assiut, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fahad","family":"Alshanbari","sequence":"additional","affiliation":[{"name":"Department of Medical Biosciences, College of Veterinary Medicine, Qassim University","place":["Buraydah, Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s13570-020-0159-3","article-title":"Dromedary (Camelus dromedarius) and Bactrian camel (Camelus bactrianus) crossbreeding husbandry practices in Turkey and Kazakhstan: an in-depth review","volume":"10","author":"Dioli","year":"2020","journal-title":"Pastoralism"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0378-4320(99)00017-2","article-title":"Seasonal effects on fertility and ovarian follicular growth and maturation in 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