{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:58:40Z","timestamp":1787497120005,"version":"build-2736575974"},"reference-count":60,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Rabies, a neglected tropical disease, causes about 59,000 annual human fatalities globally, the majority of which result from dog bites. Although rabies is preventable by vaccinating dogs and providing post-exposure prophylaxis (PEP) to humans, dog vaccination coverage in Uganda remains low at approximately 10% and not all human dog bite cases receive PEP. This study sought to understand barriers to dog bite case management and dog rabies vaccination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study, conducted between September 2022 and March 2023, involved 10 focus group discussions (FGDs) with dog owners and eight key informant interviews (KIIs) with opinion leaders, veterinary and health professionals. Participants were purposively selected based on their experience with dog vaccination and bite case management. Data was collected from Soroti Municipality (peri-urban) and Kamuda sub-county (rural) using structured interview guides premised on the socio-ecological model. Transcripts were coded and analyzed thematically using NVivo software (version 12.0).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At the individual level, limited first aid knowledge, few available PEP doses and high PEP costs were major barriers to proper dog bite case management. Community level barriers included poor management of roaming dogs and insufficient knowledge on managing biting dogs. Organizational barriers included frequent PEP stock-outs, improper cold-chain system in health facilities and poor communication between relevant health sectors. Regarding dog rabies vaccination, individual level barriers were, uncertainty about vaccination frequency, high vaccine costs and irresponsible dog ownership. Community level barriers centered on inadequate communication about dog vaccination campaigns and poor communication between the dog owners and veterinary officers, while organizational barriers included inaccurate data on dog population, inadequate staffing and logistical constraints.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The study\u2019s findings revealed that effective rabies prevention is constrained by interrelated individual, community and systemic factors. To address these gaps, district health authorities should provide continuous community education on dog bite first aid and timely seeking of care, ensure consistent availability of PEP through improved supply chain management, and implement subsidized or free mass dog vaccination campaigns. In addition, local governments should improve dog registration systems and enforce responsible dog ownership, while strengthening coordination between human and animal health sectors through One Health approaches.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fvets.2026.1814100","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T16:31:00Z","timestamp":1779899460000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Barriers to dog bite case management and dog rabies vaccination in Soroti district, Uganda"],"prefix":"10.3389","volume":"13","author":[{"given":"Terence","family":"Odoch","sequence":"first","affiliation":[{"name":"Department of Biosecurity, Ecosystems and Veterinary Public Health, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doreen","family":"Agado","sequence":"additional","affiliation":[{"name":"Department of Biosecurity, Ecosystems and Veterinary Public Health, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salome","family":"D\u00fcrr","sequence":"additional","affiliation":[{"name":"Veterinary Public Health Institute, Vetsuisse Faculty, University of Bern","place":["Bern, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel George","family":"Okech","sequence":"additional","affiliation":[{"name":"Veterinary Public Health Institute, Vetsuisse Faculty, University of Bern","place":["Bern, Switzerland"]},{"name":"Department of Veterinary Pharmacy, Clinical and Comparative Medicine, School of Veterinary Medicine and Animal Resources, Makerere University","place":["Kampala, Uganda"]},{"name":"Graduate School for Cellular and Biomedical Sciences, University of Bern","place":["Bern, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliet","family":"Kiguli","sequence":"additional","affiliation":[{"name":"Department of Community Health and Behavioral sciences, School of Public Health, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clovice","family":"Kankya","sequence":"additional","affiliation":[{"name":"Department of Biosecurity, Ecosystems and Veterinary Public Health, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dickson","family":"Akankwatsa","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]},{"name":"Department of Global Health Security, Infectious Disease Institute, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Hartnack","sequence":"additional","affiliation":[{"name":"Section of Epidemiology, Vetsuisse Faculty, University of Zurich","place":["Zurich, Switzerland"]},{"name":"Clinical Department for Livestock and Transformation of Food Systems Centre for Veterinary Public Health and One Health, University of Veterinary Medicine","place":["Vienna, 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symptomatically identifiable furious rabies in India: a nationally representative mortality survey","volume":"6","author":"Suraweera","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1965","DOI":"10.1016\/s0264-410x(02)00778-8","article-title":"A dog rabies vaccination campaign in rural Africa: impact on the incidence of dog rabies and human dog-bite injuries","volume":"21","author":"Cleaveland","year":"2003","journal-title":"Vaccine"},{"key":"ref43","first-page":"1","article-title":"WHO Expert Consultation on rabies","volume":"931","author":"Briggs","year":"2005","journal-title":"World Health Organ Tech Rep Ser"},{"key":"ref44","first-page":"1","volume-title":"WHO Guide for Rabies Pre and Post-Exposure Prophylaxis in Humans","year":"2014"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1186\/s12889-018-5888-5","article-title":"Epidemiology and surveillance of human animal-bite injuries and rabies post-exposure prophylaxis, in selected counties in Kenya, 2011-2016","volume":"18","author":"Ngugi","year":"2018","journal-title":"BMC Public Health"},{"key":"ref46","first-page":"1","article-title":"Access to rabies post-exposure prophylaxis in tanzania: a mixed-methods and theoretically-informed study to inform policy and practise","author":"Lushasi","year":"2025"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"e982","DOI":"10.1371\/journal.pntd.0000982","article-title":"Evaluation of cost-effective strategies for rabies post- exposure vaccination in low-income countries","volume":"5","author":"Hampson","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"ref48","doi-asserted-by":"crossref","DOI":"10.1186\/s12889-015-2521-8","article-title":"Charting the evolution of approaches employed by the Global Alliance for Vaccines and Immunizations (GAVI) to address inequities in access to immunization: a systematic qualitative review of GAVI policies, strategies and resource allocation mechanisms through an equity lens (1999\u20132014).","volume-title":"BMC Public Health 15","author":"Gandhi","year":""},{"key":"ref49","doi-asserted-by":"publisher","first-page":"e3310","DOI":"10.1371\/journal.pntd.0003310","article-title":"Knowledge, attitudes and practices (KAP) about rabies prevention and control: a community survey in Tanzania","volume":"8","author":"Sambo","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"ref50","first-page":"1","volume-title":"Encyclopedia of Global Bioethics Chapter: Veterinary Ethics Publisher: Springer-Verlag Berlin Heidelberg","author":"Kimera","year":"2015"},{"key":"ref51","volume-title":"Mass Dog Culling is not an Effective Method for Rabies Control","year":"2025"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.cimid.2012.10.008","article-title":"Surveillance guidelines for disease elimination: a case study of canine 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