{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T04:55:09Z","timestamp":1776401709036,"version":"3.51.2"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Pemphigus foliaceus (PF) is the most common autoimmune skin disease in cats. Long-term immunosuppressive therapy increases susceptibility to opportunistic infections. Methicillin-resistant\n                      <jats:italic>Staphylococcus pseudintermedius<\/jats:italic>\n                      (MRSP) is an emerging multidrug-resistant pathogen in companion animals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case description<\/jats:title>\n                    <jats:p>An 8-year-old spayed female Abyssinian cat with PF, managed with prednisolone and cyclosporine, developed localized superficial pyoderma caused by MRSP despite prior systemic antimicrobial therapy. Upon diagnosis of MRSP, systemic antibiotics were discontinued, and reinforcement of a strict regimen using 2% chlorhexidine and 10% povidone\u2013iodine with topical gentamicin therapy led to complete resolution of the lesions. The patient achieved dermatologic remission without recurrence, allowing successful tapering and discontinuation of immunosuppressive therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case suggests that localized MRSP skin infections in selected feline patients receiving immunosuppressive therapy may be successfully managed with topical-based management alone. Such an approach supports antimicrobial stewardship in veterinary medicine, highlighting that topical therapy may be considered a reasonable first step in selected patients with localized superficial skin infections before escalating to systemic antimicrobials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fvets.2026.1822252","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T04:14:24Z","timestamp":1776399264000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Resolution of a cutaneous infection with methicillin-resistant Staphylococcus pseudintermedius with topical therapy in a cat with pemphigus foliaceus"],"prefix":"10.3389","volume":"13","author":[{"given":"Sin-Wook","family":"Park","sequence":"first","affiliation":[{"name":"Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program for Creative Veterinary Science Research Center, Chonnam National University","place":["Gwangju, Republic of Korea"]},{"name":"SKY Animal Medical Center","place":["Gwangju, Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Veterinary Internal Medicine, College of Veterinary Medicine, Jeju National University","place":["Jeju, Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woong-Bin","family":"Ro","sequence":"additional","affiliation":[{"name":"Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program for Creative Veterinary Science Research Center, Chonnam National University","place":["Gwangju, Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Min","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program for Creative Veterinary Science Research Center, Chonnam National University","place":["Gwangju, Republic of Korea"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s12917-018-1739-y","article-title":"Feline pemphigus foliaceus: original case series and a comprehensive literature review","volume":"15","author":"Bizikova","year":"2019","journal-title":"BMC Vet Res"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1111\/j.1365-3164.2003.00347.x","article-title":"Feline pemphigus foliaceus: a retrospective analysis of 57 cases","volume":"14","author":"Preziosi","year":"2003","journal-title":"Vet Dermatol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"162","DOI":"10.4103\/0972-5229.117054","article-title":"Sepsis induced immunosuppression: implications for 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