{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:03:39Z","timestamp":1784127819271,"version":"3.55.0"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"<jats:p>\n                    This case is the first to describe a selective immunoglobulin A deficiency (sIgAD) in a Bernadoodle with recurrent multi-drug-resistant (MDR) pneumonia and a chronic enteropathy. The patient experienced chronic coughing and regurgitation from puppyhood, and advanced imaging and endoscopic procedures documented MDR\n                    <jats:italic>Bordetella bronchisceptica<\/jats:italic>\n                    (Bb) and Mycoplasma infections. Serum immunology testing documented sIgAD. Clinical signs have been well-managed with long-term prophylactic antibiotics, anti-inflammatory steroids, probiotics, and hydrolyzed protein diet. Low serum IgA levels have not been previously documented in the Bernese Mountain dog nor designer cross breeds, such as the Bernadoodle.\n                  <\/jats:p>","DOI":"10.3389\/fvets.2026.1830827","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T14:05:31Z","timestamp":1784124331000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Multi-drug-resistant pneumonia and chronic enteropathy in a Bernadoodle with selective IgA deficiency"],"prefix":"10.3389","volume":"13","author":[{"given":"Marselle","family":"Kovarsky","sequence":"first","affiliation":[{"name":"VCA Animal Hospitals","place":["Los Angeles, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Rifkin","sequence":"additional","affiliation":[{"name":"VCA Animal Hospitals","place":["Los Angeles, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khelsea","family":"Bahr","sequence":"additional","affiliation":[{"name":"VCA Animal Hospitals","place":["Los Angeles, CA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"S10","DOI":"10.1016\/j.cpa.2007.04.005","article-title":"Immune system development in the dog and cat","volume":"137","author":"Day","year":"2007","journal-title":"J Comp Pathol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1515\/cclm.1992.30.11.775","article-title":"Concentrations in serum of IgG, IgM and IgA and their age-dependence in beagle dogs as determined by a newly developed enzyme-linked-immunosorbent-assay (ELISA)","volume":"30","author":"Schreiber","year":"1992","journal-title":"Eur J Clin Chem Clin 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