{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T02:26:56Z","timestamp":1788488816523,"version":"build-2803163510"},"reference-count":48,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Vet. Sci."],"abstract":"\n Background and aim<\/jats:title>\n Pneumonia is the most prevalent respiratory infection in sheep, significantly impacting their health and welfare. This study aimed to isolate Pasteurella spp. and other bacterial organisms from pneumonic sheep lungs and also assess their antibiotic susceptibility.<\/jats:p>\n <\/jats:sec>\n \n Materials and methods<\/jats:title>\n A cross-sectional abattoir-based study was conducted at Tamale and Kumasi abattoirs. Seventy-five ovine pneumonic lungs were randomly sampled to culture and isolate bacterial organisms associated with ovine pneumonia. The Kirby-Bauer disk diffusion method was utilized to evaluate antibiotic susceptibility.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Among the 75 pneumonic lungs that were cultured,\n Mannheimia haemolytica<\/jats:italic>\n was the predominant Pasteurella species, isolated from 54.7% of samples. Other bacteria identified included\n Staphylococcus aureus<\/jats:italic>\n (46.7%),\n E. coli<\/jats:italic>\n (37.3%), and\n Klebsiella spp<\/jats:italic>\n . (19.7%).\n M. haemolytica<\/jats:italic>\n was particularly associated with broncho-interstitial pneumonia (29.3%) and interstitial pneumonia (17.3%), while\n P. multocida<\/jats:italic>\n was prominent in interstitial cases (13.3%). Both\n M. haemolytica<\/jats:italic>\n and\n P. multocida<\/jats:italic>\n contributed to 8.0% of bronchopneumonia cases. Seasonal patterns showed\n M. haemolytica<\/jats:italic>\n (30%) and\n P. multocida<\/jats:italic>\n (16%) were more common in the dry season, whereas\n Staphylococcus aureus<\/jats:italic>\n was more prevalent in the wet season.\n M. haemolytica and P. multocida<\/jats:italic>\n were most frequently identified in 2\u20133-year-old sheep from Sahelian breeds. All bacteria were isolated from sheep in poor body condition, but no significant associations were found between breeds, body condition, and pneumonia forms (\n p<\/jats:italic>\n &gt; 0.05).\n M. haemolytica<\/jats:italic>\n and\n P. multocida<\/jats:italic>\n were highly susceptible to cefotaxime (95%, 100%) and ciprofloxacin (83%, 91%), but exhibited resistance to amoxicillin and doxycycline.\n Staphylococcus aureus<\/jats:italic>\n showed sensitivity to gentamicin (94%) and cefoxitin (71%), but resistance to tetracycline (63%).\n Pseudomonas spp<\/jats:italic>\n . was completely susceptible to gentamicin, meropenem, and amikacin (all 100%) while resistant to tetracycline (100%) and sulfamethoxazole (75%).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Mannheimia haemolytica<\/jats:italic>\n was the most prevalent bacterial pathogen isolated from pneumonic sheep lungs in this study, suggesting its primary role in ovine pneumonia.\n Staphylococcus aureus, E. coli, Klebsiella spp., Pseudomonas spp., Enterobacter<\/jats:italic>\n , and\n Citrobacter spp<\/jats:italic>\n are also prevalent. These bacteria are mostly effectively inhibited by antibiotics such as cefotaxime, ciprofloxacin, and gentamicin, but they are not susceptible to amoxicillin, tetracycline, and penicillin G.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fvets.2026.1834690","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T04:34:14Z","timestamp":1778214854000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Isolation and identification of Pasteurella species and other bacterial organisms from ovine pneumonic lungs and their antimicrobial susceptibility in Ghana: abattoir-based study"],"prefix":"10.3389","volume":"13","author":[{"given":"Abass","family":"Abdulai","sequence":"first","affiliation":[{"name":"School of Veterinary Sciences, University for Development Studies","place":["Tamale, Ghana"]},{"name":"School of Veterinary Medicine, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin Obukowho","family":"Emikpe","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael Deladem","family":"Folitse","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, Kwame Nkrumah University of Science and Technology","place":["Kumasi, Ghana"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,8]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"706","DOI":"10.3390\/ani15050706","article-title":"Important diseases of small ruminants in sub-Saharan Africa: a review with a focus on current strategies for treatment and control in smallholder systems","volume":"15","author":"Kimeli","year":"2025","journal-title":"Animals."},{"key":"B2","doi-asserted-by":"crossref","DOI":"10.1201\/9781003344346-21","volume-title":"Diseases of the respiratory system","author":"Abbott","year":"2024"},{"key":"B3","article-title":"Veterinary microbiology and microbial disease","author":"Quinn","year":"2011"},{"key":"B4","first-page":"48","article-title":"Etiology and antimicrobial susceptibility of bacterial isolates from ovine pneumonia","volume":"167","author":"Kumar","year":"2018","journal-title":"Small Rumin Res."},{"key":"B5","first-page":"1235","article-title":"Bacterial causes of ovine pneumonic lungs and their antimicrobial susceptibility in Ethiopia","volume":"52","author":"Gashaw","year":"2020","journal-title":"Trop Anim Health Prod."},{"key":"B6","doi-asserted-by":"publisher","first-page":"10352","DOI":"10.18697\/ajfand.71.15530","article-title":"Vegetable production, consumption and its contribution to diets along the urban\u2013rural continuum in Northern Ghana","volume":"15","author":"Chagomoka","year":"2015","journal-title":"Afr J Food Agric Nutr Dev."},{"key":"B7","doi-asserted-by":"publisher","first-page":"20","DOI":"10.4236\/jssm.2012.51003","article-title":"Animal supply and logistics activities of abattoir chain in developing countries: the case of Kumasi Abattoir, Ghana","volume":"5","author":"Frimpong","year":"2012","journal-title":"J Serv Sci Manag"},{"key":"B8","article-title":"Associated factors, pathology and vaccination strategies of caprine pneumonia in Nigeria (Doctoral dissertation)","author":"Jarikre","year":"2018"},{"key":"B9","volume-title":"Clinical Veterinary Microbiology","author":"Quinn","year":"1994"},{"key":"B10","volume-title":"Clinical Veterinary Microbiology disease","author":"Quinn","year":"2004"},{"key":"B11","volume-title":"Veterinary Microbiology and Microbial Disease.","author":"Quinn","year":"2002"},{"key":"B12","volume-title":"Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals. 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